Clonidine, weekly-effect, skin-permeable and control-released plaster

A clonidine transdermal technology, which is applied in the field of clonidine weekly transdermal controlled-release patch, can solve the problems of skin incompatibility, poor adhesiveness, allergies and inflammation easily, and achieve reduced total area and good viscosity Effect
CN1911222AInactive Publication Date: 2007-02-14LKF GUANGDONG MEDICAL
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Patent Information

Authority / Receiving Office
CN ยท China
Current Assignee / Owner
LKF GUANGDONG MEDICAL
Publication Date
2007-02-14
Estimated Expiration
Not applicable ยท inactive patent

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Abstract

A release controlled percutaneous adhesive of clonidine with long curative period (7 days) is prepared from clonidine, the pressure-sensitive adhesive prepared from solvent(cyclohexane)-type acrylate-vinyl acetate copolymer, and release controlling membrane prepared from modified ethene-vinyl acetate copolymer.
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Description

technical field

[0001] The clonidine weekly-effect transdermal controlled-release patch of the invention relates to a medicinal transdermal therapeutic system (Transdermal Therapeutic System TTS), also known as a patch. It is used for the transdermal administration of clonidine in the treatment of hypertension, child tics, ADHD, smoking cessation, drug abstinence, migraine, analgesia, and menopausal syndrome. Background technique

[0002] Clonidine is a central a2 receptor agonist, which can reduce the activity of peripheral sympathetic nerves and cause blood pressure by inhibiting the vasomotor center. Oral clonidine tablets were launched in the mid-1960s. Because of its definite curative effect, long-term use, effective protection of target organs and beneficial metabolism without side effects, long-term use is safe and reliable, so it was widely used clinically in the world in the 1970s and 1980s. Included in national pharmacopoeias and essential drug lists. Since the 1...

Claims

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