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Vapor deposition process for producing a stent-graft and a stent-graft produced therefrom

a technology of stent-graft and vapor deposition process, which is applied in the direction of prosthesis, blood vessels, catheters, etc., can solve the problems of poor blood flow pattern, prone to kinking of expanded polytetrafluoroethylene grafts, and prone to stent-graft endoprosthesis leakage therethrough

Inactive Publication Date: 2003-05-15
BOSTON SCI SCIMED INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Expanded polytetrafluoroethylene grafts, however, are subject to tearing or puncturing, leaving the stent-graft endoprosthesis prone to leakage of blood therethrough.
Furthermore, expanded polytetrafluoroethylene grafts are susceptible to kinking, which is also undesirable because it may lead to poor blood flow patterns.
Such thin-walled expanded polytetrafluoroethylene tubes, however, are not self-supporting, i.e., they cannot maintain their tubular shape without some type of mechanical support.
The lack of the self-supporting feature makes these tubes more difficult to process and handle as compared to self-supporting tubes.

Method used

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  • Vapor deposition process for producing a stent-graft and a stent-graft produced therefrom
  • Vapor deposition process for producing a stent-graft and a stent-graft produced therefrom
  • Vapor deposition process for producing a stent-graft and a stent-graft produced therefrom

Examples

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Effect test

example 1

[0058] Parylene C Stent-graft

[0059] A tubular graft with a wall thick of about one half to one thousandth of an inch, or about 10 to 25 microns, was formed by vacuum vapor of parylene C. A dimer of di-chloro-di-p-xylylene, which is commercially available from Specialty Coating Systems, Inc., IN, was placed into a vaporization chamber within a vacuum deposition system. The pressure of the system was reduced to about 0.1 torr by means of a mechanical vacuum pump.

[0060] The dimer vaporized at about xylylene, 150.degree. C. and at about 1.0 torr. The vaporized dimer entered a pyrolysis chamber. The pyrolysis chamber was at about 680.degree. C. and about 0.5 torr. The vaporized dimer was pyrolyzed into diradicals. The diradicals entered a rotating deposition chamber having a mandrel. The deposition chamber was operated at about 25.degree. C. and about 0.1 torr. The diradicals were directed towards the outer cylindrical surfaces of the mandrel. The outer cylindrical surface of the mandrel...

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Abstract

A stent-graft endoprosthesis is provided. The graft is a non-textile graft made from biocompatible polymers. The biocompatible compatible polymers include poly-para-xylylene polymeric material. The stent is also coated with a poly-para-xylylene polymeric material. The graft is formed by vacuum vapor deposition of diradicals forming the poly-para-xylylene material. The stent is also coated with the poly-para-xylylene material by vacuum vapor deposition.

Description

[0001] The present invention relates generally to a tubular implantable prosthesis having a polymeric tubular structure. More particularly, the present invention relates to a stent-graft endoprosthesis having increased biocompatibility and mechanical strength with a tubular structure formed by vapor deposition of a poly-para-xylylene material.BACKGROUND OF RELATED TECHNOLOGY[0002] An intraluminal prosthesis is a medical device used in the treatment of diseased blood vessels. An intraluminal prosthesis is typically used to repair, replace, or otherwise correct a diseased or damaged blood vessel. An artery or vein may be diseased in a variety of different ways. The prosthesis may therefore be used to prevent or treat a wide variety of defects such as stenosis of the vessel, thrombosis, occlusion or an aneurysm.[0003] One type of intraluminal prosthesis used in the repair of diseases in various body vessels is a stent. A stent is a generally longitudinal tubular device formed of biocom...

Claims

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Application Information

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IPC IPC(8): A61L29/06A61L29/08A61L31/06A61L31/10
CPCA61L29/06A61L29/085A61L31/06A61L31/10C08L65/04
Inventor DIMATTEO, KRISTIANTHISTLE, ROBERT C.
Owner BOSTON SCI SCIMED INC
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