10 results about "Diradical" patented technology

The invention belongs to the field of organic photoelectric materials, and particularly discloses a near-infrared two-region (NIR-II) multi-resonance hybrid four-free-radical molecule and preparation and application thereof, the structure of the molecule is as follows: in addition, the research on free radical materials in the aspect of NIR-II fluorescence imaging guided photo-thermal anticancer treatment is still limited, and the molecule has a wide application prospect. And the material is mainly concentrated on a double-free-radical material. A chain D-A-A-D type organic four-free-radical compound is designed and synthesized on the basis of a classical Cichibabin skeleton, the near-infrared two-region light-emitting multiple resonance hybrid four-free-radical molecular compound is high in stability and has the near-infrared two-region photoluminescence property, the near-infrared two-region light-emitting multiple resonance hybrid four-free-radical molecular compound is applied to research in biological photo-thermal anticancer treatment, and the near-infrared two-region light-emitting multiple resonance hybrid four-free-radical molecular compound has a wide application prospect. And the photo-thermal conversion efficiency of 87% is shown.

The invention discloses a method for photocatalytic synthesis of a 2, 3-dihydrobenzopyran-4-ketone compound and application of the 2, 3-dihydrobenzopyran-4-ketone compound, a triplet excitation state with a double-free-radical characteristic is formed after photoexcitation of a chromone compound, and the triplet excitation state can be subjected to hydrogen atom transfer with various substrates such as ethers, esters, alcohols, alkanes, sulfides, amines and aryl phosphine compounds, so that the 2, 3-dihydrobenzopyran-4-ketone compound is obtained. And carrying out Giese addition on the generated free radicals and an unexcited chromone compound to obtain a target product. Further biological activity evaluation shows that part of products obtained in the invention show good inhibitory activity on tobacco mosaic viruses, and the good protective activities of target compounds 3i and 4b are 67.77% and 63.63% respectively when the concentration is 500mg / L, which are equivalent to 63.83% of a control drug ningnanmycin. Therefore, the compound not only is green and efficient in synthesis method, but also has potential application value in the aspects of agricultural disease control and structure protection research.

The invention discloses a method for synthesizing an indole fused ring compound through light-induced continuous flow, which comprises the following steps: dissolving a compound shown as a formula I and a compound shown as a formula II in an organic solvent to obtain a homogeneous solution; and pumping the obtained homogeneous solution into a micro-channel reaction device provided with a light source, and reacting to obtain the indole fused ring compound as shown in the formula III. The novel condensed ring indole compound is obtained by taking nitro-aromatic hydrocarbon as a photosensitizer, absorbing energy through ultraviolet irradiation, attacking double bonds on N-Boc indole by the excited nitro-aromatic hydrocarbon to generate triple double free radicals, and carrying out cyclization reaction after electron transition. Compared with the prior art, the light-induced continuous flow reaction device is innovatively applied, the method is green, efficient, free of metal residues and mild in reaction condition, and the synthesized novel product, namely the fused heterocycle indole, has a wide application prospect in the aspect of synthesizing medical products.

The invention relates to a photo-initiated synthetic aminophenol compound method and application, and belongs to the technical field of organic synthesis. The synthesis method comprises the following steps: deprotonating a 1-hydroxybenzotriazole compound under an alkaline condition, and carrying out cracking reaction under the excitation of visible light to generate a high-activity biradical intermediate which is unstable and can be rapidly tautomerized into a more stable nitrosobenzene anion intermediate; the intermediate further reacts with cyclohexenone substances to synthesize the aminophenol derivative in one step. The method is simple and efficient, simple and convenient to operate, free of transition metal and additional oxidizing agents, simple and easily available in raw material reagent, high in product yield and capable of realizing large-scale synthesis, and a new method is provided for rapidly synthesizing the aminophenol compound. The synthesized aminophenol compound has good antibacterial activity, and especially has huge potential in the aspect of preventing and treating anthracnose of tea trees.

The invention relates to a preparation method of a diarylethene-based triplet-state biradical molecule with short wavelength emission, and belongs to the field of organic light-emitting free radical materials. According to the invention, on the basis of the existing photochromic skeleton-diarylethene, the diarylethene-based triplet-state biradical molecule which not only has photochromic property but also has luminous free radical property and has short-wavelength emission is designed and synthesized, and the diarylethene-based triplet-state biradical molecule has photochromic property and luminous free radical property; free radicals are generated in situ through photostimulation. The invention develops a technology for preparing stable light-emitting free radicals by a method for generating free radicals in situ through photostimulation, and the method is novel.

The invention belongs to the field of organic double free radicals, and particularly discloses a phosphine fused double free radical compound, a preparation method, application and a quantum sensing material, and the double free radical material has a structure shown in a formula 1. The invention also comprises a preparation method and application of the compound. The invention provides a high-stability and efficient near-infrared light-emitting phosphine fused biradical material, which can be directly post-modified based on a phosphorus center and regulate and control physical properties, has frequency addressable quantum coherence properties and microsecond-level room temperature quantum coherence time, and can be applied to the field of quantum sensing.

The invention relates to the technical field of chemical synthesis, electron paramagnetic resonance and dynamic nuclear polarization, and particularly discloses a preparation method of photo-induced diketoacid compound derived difree radicals for dynamic nuclear polarization. The preparation method comprises the following steps: firstly designing and synthesizing a double-free-radical precursor, namely a double-alpha-ketonic acid compound connected by using a proper group, and then obtaining a proper illumination condition to carry out light induction, so that the two alpha-ketonic acid structures generate free radicals through light excitation, thereby obtaining the light-induced double free radicals containing two lactic acid-like carbon free radicals. The double free radicals obtained by the method have the advantages of light-induced free radicals, and can be directly removed by heating and melting in the application process of melting DNP, so that the free radical scavenging operation is avoided. The invention provides a new thought for synthesis of double free radicals.

The application belongs to the field of organic photoelectric materials, and specifically discloses an asymmetric double free radical molecule, and the structure is: in addition, the application further discloses preparation and application of the compound. The asymmetric double free radical molecule driven by the dipole moment disclosed in the application has high stability, and the asymmetric double free radical conjugated molecule has intrinsic luminescent properties in the near-infrared two regions (monomolecular luminescence in a non-polar solvent reflects intrinsic luminescence). The application discloses that the internal dipole moment can not only regulate double free radical contribution (when the dipole moment increases to a certain degree, the double free radical index decreases, which indicates that there is a competitive relationship between charge separation and double free radical), but also affect the luminescent properties in the near-infrared two regions, and further reveal the important correlation rule of the dipole moment-free radical contribution value-luminescent properties; the application discloses that increasing the double free radical dipole moment can inhibit the general phenomenon that the molecular material emits light in the near-infrared two regions, that is, the red shift of the luminescent wavelength leads to exponential decline of the luminescent efficiency.

The application provides a stable double free radical monomolecular device containing an anchoring group and a synthesis method, which comprises a nitrogen free radical (-N • ) formed by oxidizing -NH by an oxidant, an Au-N • -p bridge-N • -Au monomolecular junction, a pyridine (-Py) anchoring group, and the nitrogen free radical is located in the middle of the pyridine (-Py) anchoring group and the Au-N • -p bridge-N • -Au monomolecular junction. Based on the technical scheme of the application, a monomolecular junction based on a nitrogen free radical is constructed, has the advantages of simple preparation, high junction rate and good stability, and lays a good foundation for efficiently and stably constructing a double free radical monomolecular device.

This invention relates to a photo-initiated method for synthesizing asymmetric azo aromatic compounds and its applications, belonging to the field of organic synthesis technology. A 1-hydroxybenzotriazole compound is deprotonated under alkaline conditions and then undergoes a cleavage reaction under visible light excitation to generate a highly reactive diradical intermediate. This intermediate is unstable and rapidly tautomerizes to a more stable nitrosophenyl anion intermediate. Under aprotic polar solvent conditions, this highly reactive intermediate is proton-quenched to obtain a highly reactive nitrosobenzene intermediate, which subsequently polymerizes with aniline compounds to generate asymmetric azo aromatic compounds. The raw materials are readily available, the synthetic route is short, the process is simple, and the products are easily separated and purified, making it suitable for large-scale synthesis. This provides a new route for the rapid preparation of asymmetric azo aromatic compounds. The synthesized asymmetric azo aromatic compounds exhibit good antibacterial activity and have significant application potential in the control of anthracnose in tea trees.