Polypeptide compositions toxic to anthonomus insects, and methods of use
Patent Information
- Authority / Receiving Office
- US · United States
- Patent Type
- Applications(United States)
- Current Assignee / Owner
- MONSANTO TECH LLC
- Publication Date
- 2003-12-11
- Estimated Expiration
- Not applicable · inactive patent
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Abstract
Description
1.0 BACKGROUND OF THE INVENTION
[0001] 1.1 Field of the Invention
[0002] The present invention relates generally to the fields of molecular biology. Methods and compositions comprising DNA sequences, and polypeptides derived from Bacillus thuringiensis for use in insecticidal formulations and the development of transgenic insect-resistant plants are provided. Novel nucleic acids obtained from Bacillus thuringiensis that encode coleopteran-toxic polypeptides are disclosed. Various methods for making and using these nucleic acids, synthetically modified DNA sequences encoding tIC851 polypeptides, and native and synthetic polypeptide compositions are also disclosed. The use of DNA sequences as diagnostic probes and templates for protein synthesis, and the use of polypeptides, fusion proteins, antibodies, and peptide fragments in various insecticidal, immunological, and diagnostic applications are also disclosed, as are methods of making and using nucleic acid sequences in the development...