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Phototherapy methods and systems

a technology of phototherapy and phototherapy technology, applied in the field of phototherapy methods and systems, can solve the problems of unaffected areas of skin, e.g., normal skin, bad damage, etc., and achieve the effects of reducing risks, increasing the effectiveness of phototherapy, and reducing skin cancer risk

Inactive Publication Date: 2006-04-20
THE GENERAL HOSPITAL CORP
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

This approach significantly reduces the number of treatments required, decreases the risk of sunburn and skin cancer, lowers treatment costs, and enhances the effectiveness of psoriasis treatment by delivering higher doses of radiation directly to affected areas, potentially saving over half of the annual phototherapy costs and reducing treatment time and space requirements.

Problems solved by technology

These dose levels are very effective at treating affected areas of skin, but would badly damage unaffected areas of skin, e.g., normal skin.

Method used

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  • Phototherapy methods and systems
  • Phototherapy methods and systems
  • Phototherapy methods and systems

Examples

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Embodiment Construction

Phototherapeutic Treatment

[0035] The invention features a method and device for delivering therapeutic ultraviolet (UV) radiation to plaques of psoriasis or other skin disorders, with little or no exposure to clinically normal skin. A collimated source of UV radiation scans, or is scanned, over a patient's body such that only plaques of psoriasis receive a therapeutic exposure dose of UV radiation.

[0036] Psoriasis responds best to UV radiation in a narrow wavelength region near 310 nm. At wavelengths longer than 310 nm, the effectiveness of radiation to treat psoriasis, i.e., the “action spectrum,” is similar to the spectrum for delayed erythema (i.e., tanning). At wavelengths shorter than 300 nm, sunburn occurs much more quickly than clearing of psoriasis. See, for example, J. A. Parrish and K. F. Jaenicke in “Action spectrum for phototherapy of psoriasis” (J. Invest. Dermatol., 76:336, 1981). High doses of UV radiation more effectively clears psoriasis. For example, exposing in...

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Abstract

The invention features methods and systems for treating inflammatory, proliferative skin disorders such as psoriasis, with ultraviolet phototherapy. The methods and systems use optical techniques to scan a patient's skin, designate areas of affected skin, and selectively deliver high doses of phototherapeutic ultraviolet radiation to the designated areas. To insure that only affected areas of skin affected are designated for the high doses of UV radiation, the methods and systems use one or more optical diagnostics that relate to independent physiological features of affected skin.

Description

CROSS-REFERENCE TO RELATED APPLICATIONS [0001] This application claims priority from provisional application 60 / 061,487, filed Oct. 8, 1997, the contents of which are incorporated herein by reference.FIELD OF THE INVENTION [0002] This invention relates to treatment of psoriasis and other proliferative skin disorders using phototherapeutic techniques. BACKGROUND OF THE INVENTION [0003] Psoriasis is a chronic, incurable, inflammatory skin condition affecting two to four percent of the world's population. Severity ranges from minor to life-threatening, and often fluctuates. Pathogenesis is unknown, but involves hereditary abnormalities of the immune system, with lymphocyte and neutrophil-mediated inflammation combined with hyperplasia of the epidermis. The epidermis proliferates at about ten times the normal rate. People with psoriasis literally leave a trail of skin flakes, and suffer from chronic itchy lesions, poor temperature regulation, fatigue from constant protein loss, and soci...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): A61N5/06A61B5/103A61B19/00
CPCA61B5/0064A61B5/0071A61B5/444A61B5/445A61N5/0616A61N5/0617A61N2005/0644A61N2005/0661A61B2090/373A61N5/067
Inventor ANDERSON, RICHARDDWYER, PETER
Owner THE GENERAL HOSPITAL CORP
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