52 results about "Optical diagnostics" patented technology

A method for real-time optical diagnostics in laser ablation and laser processing of layered or structured materials or material structures. Diagnostics is provided during laser ablation that is utilized regularly in laser processing and / or chemical analysis of structured materials, by means of measuring optical emission generated as a result of the pulsed laser-material interaction in real time. The method can involve a single-layer-film or a stack of multiple layers or a structure of different domains. The method is particularly beneficial in fabrication of thin-film structures, such as photovoltaic and electronic devices or circuits of devices.

A spark delivery system for generating a spark using a laser beam is provided, and includes a laser light source and a laser delivery assembly. The laser delivery assembly includes a hollow fiber and a launch assembly comprising launch focusing optics to input the laser beam in the hollow fiber. The laser delivery assembly further includes exit focusing optics that demagnify an exit beam of laser light from the hollow fiber, thereby increasing the intensity of the laser beam and creating a spark. Other embodiments use a fiber laser to generate a spark. Embodiments of the present invention may be used to create a spark in an engine. Yet other embodiments include collecting light from the spark or a flame resulting from the spark and conveying the light for diagnostics. Methods of using the spark delivery systems and diagnostic systems are provided.

The invention features methods and systems for treating inflammatory, proliferative skin disorders, such as psoriasis, with ultraviolet phototherapy. The methods and systems use optical techniques to scan a patient's skin, designate areas of affected skin, and selectively deliver high doses of phototherapeutic ultraviolet radiation to the designated areas. To insure that only affected areas of skin affected are designated for the high doses of UV radiation, the methods and systems use one or more optical diagnostics that relate to independent physiological features of affected skin.

Devices, systems, and methods that facilitate optical analysis, particularly for the diagnosis and treatment of refractive errors of the eye. An optical diagnostic method for an eye includes obtaining a sequence of aberration measurements of the eye, identifying an outlier aberration measurement of the sequence of aberration measurements, and excluding the outlier aberration measurement from the sequence of aberration measurements to produce a qualified sequence of aberration measurements. The sequence of aberrations measurements can be obtained by using a wavefront sensor. An optical correction for the eye can be formulated in response to the qualified sequence of aberration measurements.

A modular system for optical diagnosis of a sample includes a portable optical probe, a light source, a filter, and a gain detector. A first optical element releasably, optically couples the optical probe to the light source. A second optical element releasably, optically couples the optical probe to the filter and a third optical element releasably, optically couples the filter to the gain detector. The optical probe receives an optical signal from the light source via the first optical element and directs the optical signal onto the sample, thereby inducing fluorescence emission from the sample. The optical probe receives the fluorescence emission from the sample and transmits to the filter via the second optical element. The filter transmits the fluorescence emission to the gain detector via the third optical element. The optical head includes a beam splitter which reflects the fluorescence emission from the sample to the filter.

The invention features methods and systems for treating inflammatory, proliferative skin disorders such as psoriasis, with ultraviolet phototherapy. The methods and systems use optical techniques to scan a patient's skin, designate areas of affected skin, and selectively deliver high doses of phototherapeutic ultraviolet radiation to the designated areas. To insure that only affected areas of skin affected are designated for the high doses of UV radiation, the methods and systems use one or more optical diagnostics that relate to independent physiological features of affected skin.

A method and apparatus for real-time monitoring of the substrate and the gaseous process environment in a semi-conductor process step is described. The method uses infrared spectroscopy for in-situ analysis of gaseous molecular species in the process region and characterization of adsorbed chemical species on a substrate. The process monitoring can be applied to endpoint-and fault detection in etching and deposition processes, in addition to chamber cleaning and chamber condition steps.

A structure is configured to retain optical diagnostic assay components in a manner that enables them to be synergistically combined or coupled both mechanically and electrically with a conventional mobile electronic device (such as a smartphone), such that the pairing maintains a mutually advantageous relationship to provide a compact portable optical assay apparatus in which the optical assay portion has access to the image sensor, battery power, microprocessor, and data capture, analysis, storage, display and transmission capabilities of the smartphone, and the smartphone portion provides the overall apparatus with features of transportability, user interface, and information storage, analysis and retrieval, and transmission of assay results to a separate site, such as a site of records related to the provider of the sample being assayed. Methods of providing such structure and of performing an optical assay of sample material utilizing such structure are described.

A readhead for a photometric diagnostic instrument includes a holder configured for receiving reagent sample media therein. The sample media has a plurality of test areas configured to react with, and change color, according to an amount of an analyte in a sample. The holder is sized and shaped for forming an indexed fit with the sample media. One or more light sources are configured to emit light onto the test areas. First and second polarized light filters are respectively disposed between the light sources and the test areas, and between the test areas and one or more light detectors, so that the light detectors receive diffuse, non-specular reflections of the light from the test areas, while substantially preventing the light detectors from receiving specular reflections of the light.

A self-contained, optical hand-held diagnostic device is provided with a body having a pocket-sized form factor sized and shaped for engagement by a user's hand. The body includes an integral power supply and an integral display. A channel receives reagent sample media in an indexed fit. The sample media has a plurality of spaced test areas which change color according to an amount of a constituent or property in the sample. Imagers are located within the body so that each of the imagers is superposed with one of the test areas when the sample media is indexed within the channel, to capture an image thereof. A processor is coupled with the imagers to analyze the captured images. The processor also derives a diagnosis value from the analysis, and generates an output corresponding thereto. The display is configured to receive and display the output.

A handwriting authentication and verification method based on single character characterized by that, four traverse line element characteristic is extracted to better reflect the feature of the Chinese characters, then one of the following methods is used to reflect the optical diagnostic character of the difference between different writers, one is to extract the most distinctive feature through direct LDA (linear differentiation analysis) transformation, the other is to first extract the most distinctive feature through direct PCA (principal component analysis) transformation dimensionality reduction, then using LDA transformation to obtain the most distinctive diagnostic character. In accordance with the invention, an Euler's distance classifier is used for categorization authentication.íí

The invention relates to an optical diagnostic system on the basis of laser spontaneous Raman scattered ray imaging, belonging to the technical field of laser spectrum testing. According to the invention, a laser pulse shaper is arranged between a laser and a gas sample tank; a cutoff device is arranged at one end of a laser emergence quartz window of the gas sample tank; a total reflective mirror is arranged between an outlet of a scattered ray output quartz window of the gas sample tank and a line light source collector at an angle of 45 degrees; an optical filter is arranged between the line light source collector and an inlet of a spectrometer; an outlet of the spectrometer is respectively connected with an ICCD (Intensified Charge Coupled Device) and an inlet of a measurement and control machine; the ICCD is also respectively connected with the laser and the measurement and control machine; and due to the adoption of the optical diagnostic system, the phenomena of gas fracturing,damage to optical elements and the quartz windows, ignition of inflammable gases and the like can be effectively avoided, the weak Raman scattering signal to noise ratio can be effectively improved, and a multichannel gas Raman spectrum experiment proves that the optical diagnostic system can be applied to synchronous quantitative measurement in a plurality of regions of the gas mixture concentration in an optical engine.

A miniature readhead for a photometric diagnostic instrument includes a housing of hand-held form factor, configured for receiving reagent sample media therein. The sample media has a plurality of test areas configured to react with, and change color, according to an amount of an analyte in a sample. The holder is sized and shaped for forming an indexed fit with the sample media and includes an array of light sources coupled to the housing, each of the light sources configured to emit light onto a respective one of the test areas. An array of chambers respectively containing an array of light detectors, is configured to enable each of the light detectors to receive diffuse, non-specular reflections of the light from the test areas, while substantially preventing the light detectors from receiving specular reflections of the light.

The invention relates to an experimental device and method for obtaining annular uniform plasma in atmospheric pressure air, belonging to the technical field of plasma. The tubular ground electrode (3) is tightly wrapped around the quartz dielectric tube (2), pasted and fixed, and grounded firmly through the wire; the tubular high-voltage electrode (1) is inserted into the quartz dielectric tube (2), and the tubular high-voltage electrode (1 ) is at the position slightly below the bottom of the ground electrode (3), and the tubular high-voltage electrode (1) is connected to the bipolar nanosecond pulse power supply (4) through a wire; the tubular high-voltage electrode (1) and the tubular ground electrode (3) An annular discharge area is formed between them. The discharge plasma is excited by a bipolar nanosecond pulse power supply (4), and an electrical diagnosis system, an optical diagnosis system, and an image acquisition system are used to perform real-time characteristic diagnosis on the generated annular surface plasma.

A method for allocating faults in a passive optical network (PON) by placing a number of passive unique optical correlators in a number of respective diagnostic points of the PON, each of the passive unique optical correlators being responsive to an optical diagnostic signal by returning a predetermined unique matching signal; by further transmitting the diagnostic optical signal in the PON towards the diagnostic points to receive upstream response signals from the correlators. Upon detecting presence or absence, in the received response signals, of a predetermined unique matching signal expected from a specific optical correlator, judging about a fault in proximity of the respective specific diagnostic point.

A readhead for a photometric diagnostic instrument includes a housing adapted for incorporation within the photometric diagnostic instrument, and an elongated sample table operatively engaged with the housing. The sample table is configured to support elongated reagent sample media of the type having a plurality of test areas disposed in spaced relation thereon, each of the test areas being configured to react with a sample and to change color according to an amount of a constituent or property in the sample. A light source is provided to illuminate the sample table. An imager having an elongated field of view is coupled to the housing, the elongated field of view including at least a portion of the sample table. A scanning mechanism is configured to move the field of view relative to the sample table.

A sensor apparatus and methods for facilitating combustion of a gaseous fuel are provided. The sensor apparatus comprises a combustion apparatus defining a combustion chamber therein. The combustion apparatus is configured to combust a fuel-air mixture within the combustion chamber to produce at least one combustion product. At least one optical diagnostic apparatus is coupled to the combustion apparatus for measuring at least one property of the at least one combustion product within the combustion chamber. A controller is coupled to the at least one optical diagnostic apparatus, and is configured to determine the Wobbe index of the fuel in real-time based on the measured at least one property of the at least one combustion product and pre-determined combustion state data stored within the controller.

A method and apparatus for real-time monitoring of the substrate and the gaseous process environment in a semi-conductor process step is described. The method uses infrared spectroscopy for in-situ analysis of gaseous molecular species in the process region and characterization of adsorbed chemical species on a substrate. The process monitoring can be applied to endpoint- and fault detection in etching and deposition processes, in addition to chamber cleaning and chamber condition steps.

A method for real-time optical diagnostics in laser ablation and laser processing of layered or structured materials or material structures. Diagnostics is provided during laser ablation that is utilized regularly in laser processing and / or chemical analysis of structured materials, by means of measuring optical emission generated as a result of the pulsed laser-material interaction in real time. The method can involve a single-layer-film or a stack of multiple layers or a structure of different domains. The method is particularly beneficial in fabrication of thin-film structures, such as photovoltaic and electronic devices or circuits of devices.

A structure is configured to retain optical diagnostic assay components in a manner that enables them to be synergistically combined or coupled both mechanically and electrically with a conventional mobile electronic device (such as a smartphone), such that the pairing maintains a mutually advantageous relationship to provide a compact portable optical assay apparatus in which the optical assay portion has access to the image sensor, battery power, microprocessor, and data capture, analysis, storage, display and transmission capabilities of the smartphone, and the smartphone portion provides the overall apparatus with features of transportability, user interface, and information storage, analysis and retrieval, and transmission of assay results to a separate site, such as a site of records related to the provider of the sample being assayed. Methods of providing such structure and of performing an optical assay of sample material utilizing such structure are described.

A miniature readhead for a photometric diagnostic instrument includes a housing of hand-held form factor, configured for receiving reagent sample media therein. The sample media has a plurality of test areas configured to react with, and change color, according to an amount of an analyte in a sample. The holder is sized and shaped for forming an indexed fit with the sample media and includes an array of light sources coupled to the housing, each of the light sources configured to emit light onto a respective one of the test areas. An array of chambers respectively containing an array of light detectors, is configured to enable each of the light detectors to receive diffuse, non-specular reflections of the light from the test areas, while substantially preventing the light detectors from receiving specular reflections of the light.

An optical diagnosing instrument for observing human eye iris and obtaining the image and data of iris at same time is composed of the optical camera-computer channel and the optical channel for visual observation, which device the light axises perpendicular to each other. Said optical channel for camera and computer consists of collimator, reflector, incident surface of prism, focusing lens and camera connected to computer via A / D converter. Said optical channel for visual observation has focusing lens for observation and binocular eyepiece. Its advantages are more functions, high diagnosingefficiency and high correctness.

Three-dimensional surface illumination using curved laser sheets is described for optical flow measurements over conformal curved surfaces. The illumination method is applicable to many different optical-based flow visualization and measurement techniques, particularly for particle image velocimetry. An alignment sheet increases the accuracy of determining the position and movement of particles used in optical-base fluid flow techniques.

A parallel mounted MEMs optical diagnostic switch disposed within an optical connector for directing optical signals from one or a plurality of light sources to one or a plurality of light collectors by activating a feedback loop through the use of micro electro mechanical systems (MEMS). The present invention includes one or more mirrors mounted parallel to the path of optical transmission through the tool. The mirrors and can be automatically activated at power up or selectively thereafter for detecting faults in any upstream fiber optic component. When in the passive mode, the present invention retracts away from the optical path so as not to interfere with normal system operations.

The present invention relates to the use of a compound of formula 3 or a salt thereof to prepare a medicament or phototherapeutic agent for treating the following diseases, including: acne; AIDS; viral hepatitis; diabetic retinopathy; SARS virus infection; coronavirus Arterial stenosis; carotid artery stenosis; intermittent claudication; Asian (chicken) avian influenza virus infection; cervical dysplasia or various cancers, including: blood cancer, cervical cancer, nasopharyngeal cancer, tracheal cancer, laryngeal cancer, bronchial cancer , bronchiolar cancer, bladder cancer, esophageal cancer, stomach cancer, rectal cancer, colon cancer, prostate cancer, hollow organ cancer, bile duct cancer, urinary tract cancer, kidney cancer, uterine cancer, vaginal cancer and other gynecological adnexal cancer. The present invention also relates to methods of treating the above diseases. The present invention further relates to the use of the compound of formula 3 or a salt thereof to prepare a photodiagnostic agent for detecting the above-mentioned diseases and the following diseases, including: atherosclerosis, multiple sclerosis, diabetes, arthritis, rheumatism Arthritis, fungal infections, viral infections, chlamydial infections, bacterial infections, or parasitic diseases, HIV viral infections, hepatitis, herpes simplex, shingles, psoriasis, cardiovascular disease, and skin diseases. The present invention also relates to methods for detecting the above diseases using photodiagnostic agents. The present invention further relates to a method for low-temperature sterilization of surgical devices or other devices, including the steps of: providing a compound of Chemical Formula 3 or a salt thereof on the device; and subjecting the device to radiation treatment or sonication treatment. The invention further relates to a compound of formula 3 or a salt thereof linked or attached to a magnetic element. This compound acts as an MRI enhancer. The invention also relates to the use of such MRI enhancers for performing MRI scans.

A system and method for launching and characterizing filaments are provided using an aerodynamic window. A filament, a self-induced waveguide in air, is produced by high power laser pulses traversing the atmosphere that can self-focus due to the nonlinear index of refraction of air. At some critical power, self-focusing overcomes diffraction in the atmosphere and the beam collapses until it is balanced by some higher order effect, usually plasma de-focusing. The use of an aerodynamic window provides an opening for a laser beam to propagate between two different atmospheric regions without the use of a solid window, such as between the atmosphere and a vacuum. An aerodynamic window provides a means for controllably launching a filament into the atmosphere. Additionally, an aerodynamic window allows for the characterizing evaluation of a filament without damage to the optical diagnostic tools.

An electromagnetic radiation diffuser, operative at extreme ultraviolet (EUV) wavelengths, is fabricated on a substrate. The diffuser comprises a randomized structure having a peak and valley profile over which a highly reflective coating is evaporated. The reflective coating substantially takes the form of the peak and valley profile beneath it. An absorptive grating is then fabricated over the reflective coating. The grating spaces will diffusely reflect electromagnetic radiation because of the profile of the randomized structure beneath. The absorptive grating will absorb the electromagnetic radiation. The grating thus becomes a specialized Ronchi ruling that may be used for wavefront evaluation and other optical diagnostics in extremely short wavelength reflective lithography systems, such as EUV lithography systems.

A slapper detonator which integrally incorporates an optical wavequide structure for determining whether there has been degradation of the explosive in the explosive device that is to be initiated by the detonator. Embodiments of this invention take advantage of the barrel-like character of a typical slapper detonator design. The barrel assembly, being in direct contact with the energetic material, incorporates an optical diagnostic device into the barrel assembly whereby one can monitor the state of the explosive material. Such monitoring can be beneficial because the chemical degradation of the explosive plays an important in achieving proper functioning of a detonator / initiator device.