Methods and devices for denervation

a technology of denervation and denervation tube, which is applied in the field of denervation tube methods and devices, can solve the problems of limiting the selection of particular therapeutic agents, difficult to deliver therapeutic agents with sufficient precision to the renal nerve, and toxic to the patient or surrounding tissues
US20110184337A1Inactive Publication Date: 2011-07-28NORTHWIND MEDICAL
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Patent Information

Authority / Receiving Office
US · United States
Current Assignee / Owner
NORTHWIND MEDICAL
Publication Date
2011-07-28
Estimated Expiration
Not applicable · inactive patent

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Abstract

Various delivery devices are described to deliver an agent locally to the renal nerves. The delivery devices are positioned in the renal artery and penetrate into the wall of the renal artery to deliver the agent to the renal nerves. The delivery devices may be used to deliver the agent according to longitudinal position, radial position, and depth of the renal nerves relative to the renal artery. In addition, various methods are described to denervate, modulate, or otherwise affect the renal nerves and other neural tissue. Also, various agents are described to denerve, modulate, or otherwise affect the renal nerves and other neural tissue.
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Description

BACKGROUNDA blood vessel or other bodily passage may be used to access parts of the body to deliver an agent to a target site in the wall of the vessels. For example, the renal arteries may be used as access pathways to deliver a therapeutic agent to the renal nerves, which run within the wall of the renal arteries. However, it may be difficult to deliver therapeutic agents with sufficient precision to the renal nerves. One approach is to “flood” the entire region about the circumference of the renal artery using the agent. This approach uses more of the agent than is necessary and may be toxic to the patient or surrounding tissues. Moreover, the toxicity concerns can also significantly limit the selection of particular therapeutic agents to kill nerves and the ability to provide effective treatment.What is needed is a way of locally delivering the amount of an agent needed to effect a desired therapeutic response while reducing injury or harm to surrounding tissue. What is also nee...

Claims

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