Antiadhesive Material

Abstract

An antiadhesive material is provided and contains a poly-γ-glutamic acid having a weight-average molecular weight of 600,000 to 13,000,000, or a kinematic viscosity at 37° C. of 2 cSt to 15 cSt when dissolved in distilled water at a concentration of 0.05% by mass and / or a salt thereof, as an effective ingredient. The antiadhesive material may have any form such as powder or gel form, and therefore, for example, is easy to handle even in relatively localized surgery such as endoscopic surgery and can more reliably prevent adhesion.

Description

TECHNICAL FIELD[0001]The present invention relates to an antiadhesive material, and more particularly relates to an antiadhesive material that provides high safety and favorable handleability on the surgery.BACKGROUND ART[0002]It is known that the surfaces of organs after being damaged during surgery are conjugated to surrounding tissues, and thus postoperative adhesions occur. The postoperative adhesions cause, for example, infertility due to fallopian tube adhesions, intestinal obstruction due to intestinal adhesions, and the like, and require a second surgery, which imposes a heavy burden on patients. Furthermore, the second surgery may even cause additional damage to the organs as a result of dissection of the adhesion site. In order to prevent such postoperative adhesions, an antiadhesive material in film form is known with which a wound site is physically covered on the surgery.[0003]Meanwhile, the cases of endoscopic surgery has recently been increasing because of the small w...

AI Technical Summary

Benefits of technology

This patent is about a new material that prevents organs from sticking together after surgery. It is easy to use and can be applied in small surgeries. The material does not require any ingredients from living organisms, which means it is safer to use. There is no need for crosslinking treatment, which can cause problems in manufacturing. Overall, this invention solves the problem of post-operative adhesion.

Problems solved by technology

It is known that the surfaces of organs after being damaged during surgery are conjugated to surrounding tissues, and thus postoperative adhesions occur.

The postoperative adhesions cause, for example, infertility due to fallopian tube adhesions, intestinal obstruction due to intestinal adhesions, and the like, and require a second surgery, which imposes a heavy burden on patients.

Furthermore, the second surgery may even cause additional damage to the organs as a result of dissection of the adhesion site.

However, in such endoscopic surgery, the use of a conventional antiadhesive material in film form is often difficult.

Thus, the operations are complicated.

Therefore, there are cases where the film may be broken, or where the film cannot be correctly placed on the affected part.

However, there are still problems in manufacturing, such as the control of the degree of crosslinking, with these antiadhesive materials.