Patents
Literature
Hiro is an intelligent assistant for R&D personnel, combined with Patent DNA, to facilitate innovative research.
Hiro

92 results about "Alkalinizing agent" patented technology

Alkalinizing agents are drugs used to manage disorders associated with low pH. For example, they may be used to treat acidosis due to renal failure. Used for oral or parenteral therapy, sodium bicarbonate is the commonly preferred alkalinizing agent. Others include potassium citrate, calcium carbonate, sodium lactate and calcium acetate.

Method for raising thermal denaturation temperature of hide and hide powder through THP salt-nano clay combination tannage

The invention discloses a method for raising thermal denaturation temperature of hide and hide powder through THP salt-nano clay combination tannage. The method comprises: adding softened hide or hide powder and water in a mass ratio of (0.5-1):1 to a reactor; adding a certain amount of salt and formic acid; adding THP salt and stirring for 3 to 5 hours; adding nano clay and stirring for 3 to 5 hours; extracting alkali till the pH of bath is between 5.0 and 6.0, continuing to stir for 2 hours and then standing the obtained product overnight; and stirring the obtained product for 30 minutes next day and then performing washing. The method can effectively raise the thermal denaturation temperature of hide collagen up to over 115 DEG C through the THP salt-nano clay combination tannage. Due to the specific structure of the nano clay added in the method, during alkali extraction in the later stage of tanning, tanning liquor is automatically alkalized and mitigated in effect, thereby helping to stabilize product quality, and the consumption of alkalization agent can be reduced. Meanwhile, the THP salt and the nano clay in the method containing no heavy metal salts are environment-friendly materials, and the tanning process is a clean leather-making technique.
Owner:SICHUAN UNIV

Azithromycin dosage forms with reduced side effects

An oral dosage form comprising azithromycin and an effective amount of an alkalizing agent. Preferably, said oral dosage form comprises an effective amount of an alkalizing agent and an azithromycin multiparticulate wherein said multiparticulate comprises azithromycin, a mixture of glyceryl monobehenate, glyceryl dibehenate and glyceryl tribehenate, and a poloxamer. Typically, the oral dosage form includes any suitable oral dosing means such as a powder for oral suspension, a unit dose packet or sachet, a tablet or a capsule. Additionally disclosed is an oral suspension comprising azithromycin, an effective amount of an alkalizing agent and a vehicle. Preferably, the azithromycin is in multiparticulate form wherein said multiparticulate comprises azithromycin, a mixture of glyceryl monobehenate, glyceryl dibehenate and glyceryl tribehenate, and a poloxamer. Also disclosed is a method for reducing gastrointestinal side effects, associated with administering azithromycin to a mammal, comprising contiguously administering azithromycin and an effective amount of alkalizing agent to said mammal wherein the frequency of gastrointestinal side effects is lower than that experienced by administering an equal dose of azithromycin without said alkalizing agent. Further disclosed is a method of treating a bacterial or protozoal infection in a mammal in need thereof comprising contiguously administering to said mammal a single dose of an oral dosage form wherein said oral dosage form comprises azithromycin and an effective amount of an alkalizing agent. Additionally disclosed are azithromycin multiparticulates comprising azithromycin, a surfactant; and a pharmaceutically acceptable carrier.
Owner:PFIZER INC

Amine-free voc-free metal working fluid

The present application concerns an aqueous metalworking composition comprising in a concentrate or after dilution of a concentrate with water in a diluent: 0.002 to 40 % by weight of component (a) which is a lubricity agent comprising at least one water-insoluble compound (a) having at least one hydrophobic aliphatic chain and at least one polar group and having a water solubility at 20 DEG C of less than 0.1 g / liter; 0.002 to 40 % by weight of component (b)comprising at least one water-soluble corrosion inhibiting compound(b) having a water-solubility at 20 DEG C of more than 0.1g / liter; 0.002 to 45 % by weight of at least one emulsifying and dispersing agent(c)which contains at least one emulsifying and / or dispersing compound (c) which is water-soluble, water-miscible or water-dispersable and which is selected from the group consisting of non-ionic, anionic and zwitterionic surfactants; 0.002to 30 % by weight of an alkalinity agent (d) containing at least one alkaline water-soluble compound (d) selected from the group consisting of hydroxides and carbonates; and 0.004 to 99 % by weight of a transport component(e)containing predominantly water. Further on, the present application concerns a method of use of such aqueous metalworking composition as a coolant, as a lubricant, etc., and concerns further on a method to prepare an aqueous metalworking composition and a metalworking process.
Owner:CHEMETALLGMBH

Preparation method of salt-resistant carboxymethyl starch

The invention relates to a preparation method of salt-resistant carboxymethyl starch. A mixed solvent of ethanol and isopropyl alcohol serves as a reaction medium, and multi-step modification of cassava starch is performed in slurry taking the mixed solvent as a medium. The method comprises the following specific steps: swelling the starch to prepare starch milk; adding a surfactant and performing modification such as alkalization and etherification by an 'acid pretreatment process'; and adding a crosslinking agent for a micro-crosslinking reaction. In the method provided by the invention, the surfactant is added as a penetrant, the reagent molecules are promoted to penetrate and spread into the starch particles, and the alkalization efficiency and etherification efficiency are improved; the generation of side reactions can be reduced by adding an etherifying agent before an alkalizer, thus the alkalization and etherification are carried out at the same time, and more thorough etherification reaction is guaranteed; finally, the starch is subjected to micro-crosslinking so as to improve the structure viscosity and enhance the salt resistance; the product viscosity 4% exceeds 40,000, the substitution degree is over 1.0, the salt-viscosity ratio goes beyond 0.5, and the product can be applied to multiple technical fields instead of CMC.
Owner:HANGZHOU HONGBO NEW MATERIALS

Bubble-formulation hair dye and preparation method thereof

The invention relates to a bubble-formulation hair dye and a preparation method thereof. The hair dye consists of two components, namely a component A and a component B. The component A consists of a dye mixture, a surfactant, a film forming agent, an alkalizer, water-soluble lanoline, water-soluble silicone oil, a humectant, an antioxidant, a heavy metal chelating agent and an essence and is prepared by the following steps of: adding water with the temperature between 45 and 55 DEG C to the film forming agent, and stirring for dissolution; adding the alkalizer, the water-soluble lanoline, the water-soluble silicone oil, the humectant, the antioxidant, the heavy metal chelating agent and the dye mixture, and stirring for dissolution; and finally adding the surfactant and the essence, stirring for dissolution, and filtering the mixture. The component B consists of hydrogen dioxide and phosphoric acid and is prepared by the following steps of: adding the hydrogen dioxide into water, and stirring for dissolution; adjusting the pH value to between 2 and 4 by using the phosphoric acid; and filtering the mixture to discharge the material. The hair dye is characterized in that: the production process is simple; the hair dye has the bubble formulation, is easy to spread uniformly and has good hair dyeing effect; and a user can optionally change the colour of the hair at home.
Owner:GUANGZHOU YOUNGRACE COSMETIC LTD

Cefmenoxime hydrochloride compound and synthesizing method thereof

The invention relates to the field of pharmacy, and especially related to a cefmenoxime hydrochloride compound and a synthesizing method thereof. The cefmenoxime hydrochloride compound has a formula shown below, and is prepared with a method comprising the steps that: (1) a cefoperazone precursor 7-ATCA.HCl and AE active ester are subjected to a condensation reaction under the existence of CH2Cl2and an alkalizing agent; and the obtained product is subjected to extraction, decolorization, press-filtration, neutralization, rejection filtration, and drying, such that cefmenoxime acid CMX-H is prepared; (2) the cefmenoxime acid is completely dissolved by using sodium carbonate; the obtained product is subjected to decolorization, press-filtration, neutralization, decolorization, filtration, crystallization, washing, and drying, such that a cefmenoxime hydrochloride half-finished product is prepared; a jet mill is started; and the material is crushed and is filled in aluminum bottles. According to the invention, cefmenoxime acid is prepared into crystals, such that the product purity is greatly improved, and the product quality is ensured. Also, the method provided by the invention is advantaged in small three-waste volume, simple preparation process, and low cost. Therefore, the method is suitable for the industrialized productions of our nation.
Owner:ZHEJIANG JIANFENG PHARM CO LTD

Meloxicam tablet for pet as well as preparation method and application thereof

The invention discloses a meloxicam tablet for a pet as well as a preparation method and application thereof. The meloxicam tablet for the pet is prepared from the following components: meloxicam, a basifier, a diluent, a disintegrating agent, a fluidizer, a lubricating agent and a proper amount of an adhesive, wherein the weight ratio of the meloxicam is 0.5 to 1.25 percent, and the weight ratioof the basifier is 5 to 15 percent; the meloxicam is micronized meloxicam prepared by superfine grinding; the particle size of the micronized meloxicam is not more than 75 [mu]m. The preparation method of the meloxicam tablet comprises the following steps: performing superfine grinding on the meloxicam, then uniformly mixing the disintegrating agent, the diluent and the basifier according to an equivalent increasing method to obtain a mixture, adding the adhesive into the mixture, then performing granulation to obtain wet particles, drying the wet particles, adding the fluidizer and the lubricating agent, and tabletting the mixture, thus obtaining the meloxicam tablet. The meloxicam tablet is used for preventing and treating animal joint diseases. The meloxicam tablet for the pet is high in dissolution degree, and is favorable for playing the therapeutic effect.
Owner:FOSHAN NANHAI EASTERN ALONG PHARMA CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products