5 results about "Dimethyl dicarbonate" patented technology

The invention belongs to the technical field of medicines, and particularly relates to a preparation method of a heart failure treatment drug viriciguat. Specifically, a specific starting raw material is adopted, dimethyl carbonate is used as an acylation reagent, a proper Lewis acid is used for catalysis, and the vericiguat is synthesized under a solvent-free condition. The process avoids the defects of high toxicity, strong corrosivity, difficulty in process condition control, high cost and the like caused by acylation by using methyl chloroformate or dimethyl dicarbonate in the final reaction of the existing Velciguat synthesis process route. The preparation method can be used for preparing high-purity Velciguat with high yield, and the used reagent is low in toxicity, simple and convenient to operate, green, environment-friendly, low in cost and suitable for industrial large-scale production. # imgabs0 #

Method for producing an electrolyte system that improves or increases the efficiency of an electrochemical cell, comprising a positive electrode comprising a positive lithium-based electroactive material and having a maximum potential greater than or equal to about 5 V, and a negative electrode comprising a negative electroactive material comprising lithium, the method comprising: Mixing one or more salts selected from the group consisting of: lithium bis(fluorosulfonyl)imide (LiFSI), sodium bis(fluorosulfonyl)imide (NaFSI), potassium bis(fluorosulfonyl)imide (KFSI) and combinations thereof, and a solvent comprising one or more solvents selected from the group consisting of: dimethyl carbonate (DMC), dimethyl dicarbonate (DMDC) and combinations thereof, wherein a bound fraction with an ionization potential greater than an electron affinity is formed to create an electrolyte system that is substantially free of unbound dimethyl carbonate (DMC), dimethyl dicarbonate (DMDC) and unbound bis(fluorosulfonyl)imide (FSI). - ) is, wherein one or more salts have a concentration in the electrolyte system of greater than or equal to approximately 4 M.

This invention relates to aqueous polyurethane dispersions containing at least one polyurethane, at least one organic dialkyl dicarbonate, and at least one biocidal compound different from the organic dialkyl dicarbonate, characterized in that the at least one organic dialkyl dicarbonate is selected from dimethyl dicarbonate, diethyl dicarbonate, dipropyl dicarbonate, diisopropyl dicarbonate, methyl ethyl dicarbonate, ditert-butyl dicarbonate, and / or mixtures of at least two of these, further relating to the use of the organic dialkyl dicarbonate for reducing microorganisms in aqueous polyurethane dispersions, to a method for producing aqueous polyurethane dispersions containing reduced amounts of microorganisms, and to articles, cosmetics, coatings, adhesive layers, coating formulations, adhesive formulations, and / or cosmetic formulations obtainable therefrom.

The invention discloses a synthesis process of beta, gamma-unsaturated ketone compounds, and belongs to the technical field of compound synthesis. The beta, gamma-unsaturated ketone compound is obtained through a one-step reaction under irradiation of 450-455 nm blue light in a composite catalyst system by taking allyl-containing olefin as an initial raw material, carboxylic acid as an acylating agent and dimethyl dicarbonate (DMDC) as a dehydrating agent. The composite catalyst system is a compound of a photocatalyst, NiBr2. DME, 4, 4 '-di-tert-butyl-2, 2'-dipyridyl and ammonium chloride; the photocatalyst is Ir [dF (CF3) ppy] 2 (dtbbpy) PF6, fusion of HAT and a coupling function is realized by reconstructing a catalytic system structure and utilizing a nickel-bromine synergistic free radical mechanism, the structural defects in the prior art are fundamentally overcome, and a universal platform is provided for constructing a C-C bond by directly utilizing free carboxylic acid and olefin.

The invention provides a method for prolonging the fresh-keeping period of peony and shrub althea flowers, which comprises the following steps: disinfecting stem bases of fresh-cut peony and shrub althea flowers with dimethyl dicarbonate, spraying a film coating liquid for fresh keeping, and putting the stem bases and modified fresh-keeping paper into a low-density polyethylene functional modified atmosphere bag for storage and fresh keeping. According to the invention, silk fibroin, pullulan and the like are adopted to prepare the fresh-keeping liquid, and laccase enables ellagic acid to form o-quinone which is combined with silk fibroin and the like to form a film, so that moisture diffusion and primary bacteriostasis are slowed down; in addition, lignin microspheres are prepared from composite modified lignin loaded with 1-methylcyclopropene microcapsules and limonene, preservative paper base coating liquid is formed, the modified preservative paper is obtained, release of 1-methylcyclopropene and limonene is controlled, and loss of edible quality of the peony hibiscus flowers is inhibited. According to the invention, through the cooperation of coating preservation, preservative paper and modified atmosphere preservation, the storage period of the peony shrub althea flowers is obviously prolonged, good quality characteristics of the peony shrub althea flowers are retained, and the preservation stability and practical value are improved.