6 results about "Missing kidney" patented technology

This invention discloses a traditional Chinese medicine composition for treating male infertility due to liver stagnation and kidney deficiency, its preparation method, and its application, belonging to the fields of traditional Chinese medicine pharmaceutical technology and andrological reproductive health technology. The composition is formulated with Bupleurum chinense, Tribulus terrestris, Cynomorium songaricum, Cuscuta chinensis, Cornus officinalis, and Epimedium brevicornu in specific weight proportions, following the principles of soothing the liver and relieving stagnation, tonifying the kidney and replenishing essence, and unblocking the meridians to treat impotence. This invention employs an alcohol-water dual-phase fractional extraction process, and can be prepared into various dosage forms such as granules, capsules, and tablets. Pharmacological experiments have confirmed that the composition of this invention can increase sperm density and progressively motile sperm rate, improve penile tissue nitric oxide synthase (NOS) activity, regulate reproductive hormones, and reduce testicular oxidative damage; serum pharmacochemistry and metabolomics have clarified the active components entering the bloodstream and their pathways of action. This invention features a refined formulation, abundant medicinal resources, and simple preparation, making it suitable for large-scale production and clinical application in treating male infertility due to liver stagnation and kidney deficiency.

This invention relates to a topical acupoint patch, its preparation method, and its application, comprising the following raw materials in parts by weight: 45-55 parts of Cuscuta chinensis, 45-55 parts of Psoralea corylifolia, 45-55 parts of Loranthus parasiticus, 45-55 parts of Acanthopanax senticosus, 45-55 parts of Ligusticum chuanxiong, 45-55 parts of Lycopodium clavatum, and 15-25 parts of Zanthoxylum bungeanum. The topical acupoint patch of this invention has a therapeutic effect on knee osteoarthritis, especially on knee osteoarthritis of the kidney deficiency and blood stasis type.

The invention discloses an essence-nourishing and liver-soothing composition for treating kidney deficiency, liver stagnation and spleen deficiency type premature ovarian failure and a preparation method of the essence-nourishing and liver-soothing composition, and belongs to the field of traditional Chinese medicines, the essence-nourishing and liver-soothing composition is prepared from fructus corni, radix rehmanniae preparata, radix angelicae sinensis, radix paeoniae alba, rhizoma dioscoreae, pericarpium citri reticulatae, semen cuscutae, fructus ligustri lucidi, herba lycopi and rhizoma cyperi. The essence-nourishing and liver-soothing soup is based on the essence-nourishing and seed-growing soup, is added and reduced by combining clinical practice and summarized experience, is prepared to tonify kidney and replenish essence, soothe liver, regulate and tonify Chong and Ren meridians, dredge the Ren and dredge and regulate qi and blood, effectively improves the ovarian function, and further achieves the effects of regulating menstruation and assisting pregnancy. The essence-nourishing and liver-soothing soup is mainly used for premature ovarian failure patients, and prophase clinical observation shows that the essence-nourishing and liver-soothing soup has good clinical effects in the aspects of improving serum sex hormone indexes, increasing the number of sinus follicles, promoting follicle maturation and smooth discharge and improving the success rate of pregnancy.

This invention relates to a traditional Chinese medicine composition for delaying the progression of kidney deficiency and blood stasis syndrome in diabetic nephropathy, its application, and preparation method. The composition is made from Astragalus membranaceus, Salvia miltiorrhiza, Paeonia lactiflora, Anemarrhena asphodeloides, Phellodendron chinense, Cistanche deserticola, Scutellaria baicalensis, Euonymus alatus, Schisandra chinensis, raw oyster shell, Plantago asiatica, and Artemisia annua. It has the effects of nourishing the kidneys, clearing heat, eliminating toxins, and unblocking the meridians. This traditional Chinese medicine composition can effectively delay the decline in renal function in patients with massive proteinuria during the diabetic nephropathy stage, improve the clinical symptoms of patients with kidney deficiency and blood stasis syndrome, and improve their quality of life. Simultaneously, it has a low risk of hyperkalemia and gastrointestinal bleeding, and no significant damage to liver function has been observed, indicating high safety.

The invention relates to application of toyocamycin to construction of an animal model of implantation obstacles and a construction method of the animal model of implantation obstacles, and belongs to the technical field of medicines. According to the invention, a traditional Chinese medicine combination model of the SD rat implantation disorder in accordance with the kidney deficiency and blood stasis syndrome in traditional Chinese medicine is manufactured, and the requirements of traditional Chinese medicine research are met; a stable kidney deficiency and blood stasis-embryo implantation disorder rat model is manufactured, and the modeling success rate is increased; the modeling time is only 5 days from the time of confirming that the rat is pregnant, so that the modeling time is greatly reduced; operation steps are reduced, intraperitoneal injection can be completed only through one time of intraperitoneal injection, and harm to experimental animals is reduced.

The present application relates to the use of fungacin in the construction of an animal model of implantation disorder and a method for constructing an animal model of implantation disorder, and belongs to the technical field of medicine. The present application manufactures an SD rat implantation disorder TCM syndrome combination model conforming to the kidney deficiency and blood stasis syndrome type, meeting the needs of TCM research; a stable kidney deficiency and blood stasis-embryo implantation disorder rat model is manufactured, and the success rate of modeling is improved; the modeling time of the present application is only 5 days from confirming that the rat is pregnant, greatly reducing the modeling time; the operation steps are reduced, and only one intraperitoneal injection is needed to complete, reducing the harm to experimental animals.