77 results about "Order Rodentia" patented technology

Methods for generating anti-variable region monoclonal antibodies in rodents are disclosed. The anti-variable region mAbs are useful as therapeutic agents, diagnostic agents or research reagents.

Disclosed are methods of treating cancer comprising administering to the animal, a therapeutically effective amount of a heterocyclic compound of Formula VI. The animal is a mammal, preferably a human or a rodent.

An electrically powered rodent trap which includes a surveillance system for remote surveillance of the trap so that the trap may be operated without being attended to. A rodent which enters into the trap is killed by means of electrocution electrodes. The dead rodent is automatically dispatched from the trap, e.g. by a trapdoor, into a container or reservoir beneath the trap. The number of electrocutions and possible other data is stored by an electronic system incorporated in the trap and a signal is sent out, either by request from an external unit, or automatically to an external unit. A city rodent exterminator is capable of monitoring the status of the trap from an office location and thereby effectively tend to the trap or to a series of traps.

Disclosed are methods of treating cancer comprising administering to the animal, a therapeutically effective amount of a heterocyclic compound of Formula VI. The animal is a mammal, preferably a human or a rodent.

CDR-grafted antibody heavy and light chains comprise acceptor framework and donor antigen binding regions, the heavy chains comprising donor residues at at least one of positions (6, 23) and/or (24, 48) and/or (49, 71) and/or (73, 75) and/or (76) and/or (78) and (88) and/or (91). The CDR-grafted light chains comprise donor residues at at least one of positions (1) and/or (3) and (46) and/or (47) or at at least one of positions (46,48, 58) and (71). The CDR-grafted antibodies are preferably humanised antibodies, having non human, e.g. rodent, donor and human acceptor frameworks, and may be used for in vivo therapy and diagnosis. A generally applicable protocol is disclosed for obtaining CDR-grafted antibodies.

A device for trapping and killing rodents includes a long, narrow box-like enclosure having an entrance opening at a first end through which the rodent passes face first into the enclosure, and an opposite rear end having rear wall from which a bait shelf inwardly projects for the placement of bait thereon, with a snap trap located between the entrance opening and the bait so that the rodent must walk over the trap at the trap's most lethal orientation which is straight forward thereby unavoidably triggering the trap and killing the rodent. A pair of clips positioned within the enclosure adjacent the rear wall secure the trap in position and prevent the trap from flipping up when triggered, and the both the rear wall and the roof are hinged so that they can be opened for replacing the bait without disturbing the trap and for removing both the bait and trapped rodent so that the enclosure can be re-baited and the trap reset or replaced.

A poison bait device having a poison bait container which, in operation, is accessible to rodents such as rats and mice but which is inaccessible to other creatures including humans, birds, dogs, cats and the like, wherein the only access to the bait well is thru a relatively small diameter tube having a tortuous path such as curves thru which rats and mice must slither, and wherein the entrance(s) to said tube is generally planar and adapted for sufficiently close to the ground and substantially parallel to the ground plane whereby children, pets and birds cannot reach the bait.

An embodiment of a bait station comprises a rotatable lid and air-tight bait compartments. An additional compartment also contains bait and is accessible to rodents as they enter the station. The rotatable lid is configured to hold the bait within the compartments and can be rotated in order to replace the previously accessible bait with fresh bait from a different compartment. A key can be attached to an extension pole in order to unlock and rotate the rotatable lid without requiring a person to kneel down or bend over. A base having two entrances provides an inviting environment for rodents.

Disclosed are non-human animal models, and preferably, rodent models, and more preferably, mouse models, of B-cell Non-Hodgkin's Lymphoma (NHL). In particular, the present invention provides animal models of B cell NHL including, B cell chronic lymphocytic leukemia/lymphoma (B-CLL), Burkitt's lymphoma (BL), Follicular-like lymphoma (FLL) and Diffuse large B-cell lymphoma (DLBCL), as well as various methods for producing these non-human animal models. These animal models, as well as cell lines produced from or derived from these models, are useful tools for a variety of methods, including, but not limited to, preclinical testing of drug candidates, and particularly drug candidates that are specific for human proteins, and any research, development, pharmaceutical, or clinical purpose, including but not limited to, the identification, development, and/or testing of drugs (therapeutics, prophylactics, etc.), targets, markers, and/or research tools for use in the diagnosis of, study of, or treatment of any Non-Hodgkin's Lymphoma, such as those described herein, or for any related condition.

The present invention provides a bait station and method for securing it using a receptacle for holding a weight to weight a bait enclosure and by stakes formed as a unitary part of the enclosure for securing the enclosure

A loading dock seal has one or more recesses formed within the loading dock seal and covered by a transparent material. Mesh segments are utilized to screen some of the recesses to reduce rain, snow, rodents, insects and debris from passing through the recess passageway to the loading dock. A further transparent or opaque mesh segment cover can be utilized to selectively cover one or more of the mesh segments.

A rodent trap system for alerting a user that a rodent has been trapped having a base panel, a top surface, three lips extending upwardly from three ends of the base panel wherein the lips create an enclosure, a lid pivotally attached to the second and third lips, an alarm housing on the base panel, a flange extending outwardly from the alarm housing formed by the lips which can pivot; a first half contact on a bottom surface of the flange, a second half contact on the top surface of the base panel, the contacts are connected to the actuator or solenoid and to a speaker in the alarm housing, wherein when the contacts contact each other they send an electrical signal causing the actuator or solenoid to pull a plunger to move the lid to the closed position and causing the speaker to emit the sound.

The invention discloses a grain preservative film of modified-atmosphere packaging for rat control which contains capsaicin microcapsule. The film is prepared by components of polyethylene resin, polyvinyl acetate, zinc stearate, calcium stearate, light calcium carbonate, white carbon black, paraffin wax, antioxidant and fluorescent agent. The components are weighed and mixed proportionally, extruded by a single screw plastic extruder, and subject to blow moulding to prepare a film. Capsaicin microcapsule, as a raticide, is coated on outer surface of the plastic film by an adhesive to prepare grain preservative film of modified-atmosphere packaging for rat control. The raticide slowly and continuously releases, thus achieving objective of long-term effective rat control, and has bidirectional atmosphere modifying function on O2 and CO2, with good moisture permeability of small packages, good antifogging and antisweat performance and oxidation resistance and anti aging ability.

A ridge vent end cap that can be readily bent to conform to roofs of varying pitches while enclosing ridge vents of various styles. The end caps are bent and fashioned for a flat blank, which is configured to allow it to be bent and formed into a shape that accommodates various styles of ridge vents and that encloses ridge vents on roofs with varying pitches. The bent finished end cap has a top ridge beam and a pair of end panels, bottom flaps and corner flaps. Each corner flap has its own top corner flap and a bottom corner flap. A preformed key hole slot along the central axis/plane of the blank or finished end cap allows the end cap to bend without buckling so that the end panels slide over one another to enclose the end open of the ridge vent while conforming to the pitch of the roof. A tooth is formed in one of the bottom flaps, which bites into the roof shingles helps ensure that the end panels cannot be pried up or burrowed under by rodents and insects.

The present invention provides an immunocontraceptive vaccine comprising a recombinant bacterial host that has been modified to produce egg- or sperm-specific polypeptide such as the sperm-specific protein lactate dehydrogenase-C (LDH-C). When animals such as rodents eat these bacteria, their immune systems produce antibodies that attack their sperms. Not only would the males have less viable sperm, the females would also have antibodies to sperm entering their reproductive systems. Immunocontraception is an attractive method for reducing the population size of animals with high fecundity, and sterilizing animals using such immunocontraceptives can reduce targeted animal populations to acceptable levels in an efficient, cost-effective, humane and, importantly, a species-specific manner.

Devices for repelling or discouraging rodents from accessing wires or cables on utility poles are presented, along with the method of manufacturing the same. According to preferred embodiments of the invention, a rodent-repellent additive is blended with a thermoplastic elastomer or rubber and then extruded into a tubular member that may be placed around existing cables and wires maintained by a utility pole. A squirrel or other rodent typically desiring to gnaw on the insulation or the wires themselves will be discouraged from such activity by the odor attendant to the material from which the tubular member or sleeve guard is manufactured. If not so discouraged, the taste of the material will conclusively discourage such activity. That same material may be extruded in the form of a flat, elongated extrudate cut to length to form bands that may be placed about the utility pole beneath areas requiring protection from squirrels or the like.

This invention relates to viral vector particles, including capsid proteins with an attachment site for the specific chemical modification of the vector particles. Furthermore, the invention relates to procedures for the production of these viral vector particles. Furthermore, the invention relates to the use of these viral vector particles as a therapeutic, prophylactic or diagnostic means in humans and primates as well as other vertebrates like cattle, pigs, birds, fish, or rodents.

A check valve mechanism for use with a vertical drain pipe comprises a connector portion for supporting the check valve mechanism with respect to the drain pipe, and two flaps, each being an ungula of a cylindrical tube. The flaps are pivotally connected to the connector portion, so as to be displaceable between a closed position in which the flaps are against one another such that peripheral portions of the flaps are collinear at a connection line to obstruct the drain pipe, and an opened position, in which the flaps are away from one another to allow liquids/solids to pass through the check valve mechanism and the flaps.

An irrigation tube having outlets extending along the length of the tube in a spaced relationship and finely-divided silica or iron oxide particles dispersed in the tube thereby increasing a surface hardness of the tube to deter rodent, worm or insect damage, the silica particles further can include an odor repellant located within the particles.

The invention discloses a non-metal armoring enhancement type self-supporting optical fiber cable. The optical fiber cable comprises a center reinforcing piece, loose tubes, a polyester belt, a GFRP (glass fiber reinforced plastic) layer and an outer protection layer, wherein a plurality of loose tubes are stranded on the periphery of the center reinforcing piece; single-core or multi-core optical fibers are arranged in the loose tubes filled with fiber paste; the polyester belt is longitudinally covered with the outer protection layer; the GFRP layer is stranded in the polyester belt. According to the non-metal armoring enhancement type self-supporting optical fiber cable, the design concept of a traditional metal armoring optical fiber cable is abandoned, an ADSS (all-dielectric self-supporting optic fiber cable) structure is used for reference creatively, the GFRP is arranged outside the cable for armoring, GFRP stranded armoring is performed on an inner layer of the ADSS structure, or a GFRP armoring layer is longitudinally covered with a glass fiber woven belt, so that the performance of rodent biting prevention and bird pecking prevention is achieved.

The invention discloses a multi-group co-hive and co-culture beehive and belongs to the field of apiculture and zoology. The multi-group co-hive and co-culture beehive comprises a beehive body which consists of end plates, inner side plates, outer side plates and a bottom plate; salient points are respectively arranged at two opposite sides of the bottom plate; the inner side plates and the outer side plates are erected on a hive entrance formed on the salient points of the bottom plate; a plurality of standard honeycombs are erected at the upper ends of the inner side plates; the standard honeycombs are spaced pairwise; a gap used for arranging a gate is reserved between two optional partitions of the standard honeycombs; the inner side of each end plate is provided with a dummy plate; a secondary cover is arranged above the end plates, the inner side plates, the outer side plates and the bottom plate; each dummy plate at the outermost side and the gate movably arranged jointly form a branch beehive adjustable in size. The multi-group co-hive and co-culture beehive disclosed by the invention aims to solve the defects that the cost is high, the service life is short, the rodent damage and insect damage resistance is low, the anti-theft ability is low, the feeding pattern is fixed and the temperature control capacity is low during the apiculture process by adopting the traditional wooden beehive; the feeding cost is reduced, the service life of the beehive is prolonged, the resistance to rodent damage and insect damage is improved, and the temperature control capacity of the beehive is enhanced.