1results about How to "Physically good" patented technology

This invention provides a dense honeycomb structure cross-linked sodium hyaluronate gel and its preparation method, comprising the following steps: S1. Preparing a chloride ion solution, adding a cross-linking agent, slowly adding sodium hyaluronate under stirring conditions, adjusting the pH to alkaline, and stirring evenly under vacuum conditions to obtain a mixture; S2. Maintaining vacuum conditions, heating the mixture in a water bath, cutting it to obtain a block gel, cross-linking it in a water bath to obtain a cross-linked sodium hyaluronate gel; S3. Adjusting the pH of the cross-linked sodium hyaluronate gel to neutral, performing a first vortex-shear composite grinding treatment to obtain a homogeneous paste-like gel, dialysis, then a second vortex-shear composite grinding treatment, adding non-cross-linked sodium hyaluronate and PBS solution, performing a third vortex-shear composite grinding treatment, filling, and sterilizing to obtain the dense honeycomb structure cross-linked sodium hyaluronate gel. The dense honeycomb structure cross-linked sodium hyaluronate gel obtained by this invention has smooth injection, strong support, long-lasting effect, and low adverse reaction rate.