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Ginseng and astragalis blood glucose lowering dispersion tablet and its preparing and detecting method

A technology of Shenqi hypoglycemic and dispersible tablets is applied in the field of traditional Chinese medicine dispersible tablets for the treatment of diabetes, and can solve the problems of reduced dissolution rate, precipitation of drug crystals, aging and the like

Active Publication Date: 2007-10-10
LUNAN HOPE PHARM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to the particularity of the composition of the soft capsule shell, the soft capsules prepared in my country generally have serious aging phenomena. After 1.5 years of storage, the disintegration time limit generally exceeds 40 minutes, or even does not disintegrate, which brings great harm to the storage and sales of preparations. inconvenient
Long-term storage of dropping pills will also cause aging phenomena such as precipitation of drug crystals and decrease in dissolution rate.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0133] Ginsenoside 6 parts by weight, Astragalus 124 parts by weight, Rehmannia glutinosa 186 parts by weight

[0134] 62 parts by weight of Ophiopogon japonicus, 62 parts by weight of trichosanthin, 124 parts by weight of Chinese wolfberry

[0135] Schisandra 62 parts by weight, yam 62 parts by weight, raspberry 31 parts by weight

[0136] 62 parts by weight of Poria cocos and 62 parts by weight of Alisma.

[0137] Preparation method: a Ophiopogon japonicus is extracted twice with warm water, each time for 2 hours, the extracts are combined, filtered, and the filtrate is concentrated to a thick paste with a relative density of 1.20;

[0138] b Fructus Schisandra uses 50% ethanol, percolation, percolation liquid reclaims ethanol, concentrates to thick paste;

[0139] c Lycium barbarum, astragalus, rehmannia glutinosa, Alisma, yam, trichosanthes, raspberry, and poria cocos are decocted with water twice, each time for 1.5 hours, combined with decoction, filtered, and the filtr...

Embodiment 2

[0154] 4 parts by weight of ginsenoside, 150 parts by weight of Radix Astragali, 250 parts by weight of Rehmannia glutinosa

[0155] 80 parts by weight of Radix Ophiopogon japonicus, 80 parts by weight of Trichosanthes Fen, 160 parts by weight of Lycium barbarum

[0156] Schisandra 80 parts by weight, yam 80 parts by weight, raspberry 50 parts by weight

[0157] Poria cocos 80 weight parts Alisma 80 weight parts

[0158] Preparation method: a Ophiopogon japonicus is extracted 3 times with warm water, each time for 3 hours, the extracts are combined, filtered, and the filtrate is concentrated to a thick paste with a relative density of 1.40;

[0159] b. Fructus Schisandra uses 70% ethanol, percolation, percolation liquid reclaims ethanol, concentrates to thick paste;

[0160] c Lycium barbarum, astragalus, rehmannia glutinosa, Alisma, yam, trichosanthes, raspberry, and poria cocos are decocted with water for 4 times, each time for 3 hours, combined with decoction, filtered, a...

Embodiment 3

[0175] 8 parts by weight of ginsenosides, 80 parts by weight of astragalus, and 250 parts by weight of rehmannia root

[0176] 80 parts by weight of Radix Ophiopogon japonicus, 80 parts by weight of Trichosanthes Fen, 160 parts by weight of Lycium barbarum

[0177] Schisandra 80 parts by weight, yam 80 parts by weight, raspberry 50 parts by weight

[0178] Poria cocos 80 weight parts Alisma 80 weight parts

[0179] Preparation method: a Ophiopogon japonicus is extracted once with warm water for 3 hours each time, the extracts are combined, filtered, and the filtrate is concentrated to a thick paste with a relative density of 1.30;

[0180] b Fructus Schisandra uses 50% ethanol, percolation, percolation liquid reclaims ethanol, concentrates to thick paste;

[0181] c Lycium barbarum, astragalus, rehmannia glutinosa, Alisma, yam, trichosanthes, raspberry, and poria cocos are decocted with water for 3 times, each time for 1.5 hours, combined with decoction, filtered, and the fi...

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Abstract

The present invention discloses a Shenqi sugar-reducing dispersing tablet for effectively curing diabetes with obvious therapeutic effect. Said dispersing tablet is made up by using 11 Chinese medicinal materials of ginseng (stem and leaf) saponin, astragalus root, rehmannia root, ophiopogon tuber, trichosanthes root, lyceum berry and others through a certain preparation process.

Description

technical field [0001] The invention relates to a traditional Chinese medicine dispersible tablet for treating diabetes, in particular to a Shenqi Jiangtang dispersible tablet, and to a preparation and detection method of the medicine. Background technique [0002] Diabetes mellitus is a complex disease of multiple etiologies. It is a syndrome of glucose, protein and lipid metabolism disorders caused by the lack of insulin in the body or the increase of hormones that antagonize insulin, or the inability of insulin to exert normal physiological functions in target cells. It is characterized by an abnormal increase in the concentration of glucose in the blood circulation and the typical symptoms of "three excesses and one deficiency" when the urine sugar and blood sugar are too high, that is, multiple times, polyuria, polyphagia, and weight loss, accompanied by fatigue and weakness. In severe cases, ketoacidosis and hyperosmolar diabetic coma may occur, and it is easy to be co...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/20A61K36/8968A61K36/8945A61K36/884A61K36/815A61K36/804A61K36/73A61K36/57A61K36/481A61K36/428A61K36/258A61K36/076A61P3/10G01N30/02G01N33/15
Inventor 赵志全
Owner LUNAN HOPE PHARM CO LTD