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A medicine for treating asthma, acute and chronic bronchitis and preparation method thereof

A chronic bronchitis and drug technology, applied in the direction of medical formula, drug combination, drug delivery, etc., can solve the problems of low cure rate, complications, poor clinical efficacy, etc., and achieve the effect of simple preparation process and wide range of drug sources

Inactive Publication Date: 2008-02-27
王志岐
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] At present, Western medicine for the treatment of asthma is mainly to control acute exacerbations, including adrenaline, theophylline, anticholinergics, glucocorticoids and other drugs used alone or in combination to achieve rapid relief of bronchospasm. Chronic bronchitis The treatment of acute attack and chronic protracted stage is mainly anti-infection, expectorant, and antitussive. When accompanied by wheezing, the same drugs as bronchial asthma can be used to obtain better clinical efficacy, but long-term use of the above drugs is prone to serious complications
Due to the complex etiology of asthma and large individual differences, many clinically effective prescriptions have been accumulated in the treatment of asthma with traditional Chinese medicine, such as "Dingchuan Decoction", "Mahuang Decoction", and "Maxing Shigan Decoction". Inflammation has a certain therapeutic effect, but the clinical curative effect is poor and the cure rate is low

Method used

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  • A medicine for treating asthma, acute and chronic bronchitis and preparation method thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0060] The injection preparation of embodiment 1 medicine of the present invention

[0061] Lobelia 75g Almond 30g Pinellia 30g Aristolochia 150g

[0062] Scutellaria 300g Ginkgo 30g Astragalus 150g Aster 150g

[0063] Yangjinhua 30g Schisandra 30g

[0064] The preparation method is as follows:

[0065]Weigh the raw materials Lobelia, Almond, Pinellia, Aristolochia, Scutellaria, Ginkgo, Astragalus, Aster, Dajinhua and Schisandra according to the above ratio, wash them, add water to decoct 3 times, each time the amount of water added is less than the medicine Noodles are suitable, 1 hour each time, combine the decoction, filter, concentrate and let cool; add three times the amount of 95% ethanol, leave overnight, filter; add 40% sodium hydroxide to adjust the pH value to 7-8, leave overnight, filter , the filtrate was decompressed to recover ethanol, added water for injection to adjust to 1000ml, filtered, added 10ml benzyl alcohol and 1ml Tween 80, heated for 10 minutes to ...

Embodiment 2

[0066] The oral liquid preparation of embodiment 2 medicine of the present invention

[0067] Lobelia 50g Almond 30g Pinellia 35g Aristolochia 100g

[0068] Scutellaria baicalensis 100g Ginkgo fruit 20g Astragalus 150g Aster 100g

[0069] Yangjinhua 20g Schisandra 20g

[0070] The preparation method is as follows:

[0071] Weigh the raw materials lobelia, almond, pinellia, aristolochia, baicalin, ginkgo, astragalus, aster, daguna and schisandra according to the above ratio, wash them, add water to decoct twice, each time the amount of water added is less than the medicine Noodles are suitable, each time for 1.5 hours, combine the decoction, filter, concentrate and let cool; add three times the amount of 95% ethanol, leave overnight, filter; add 40% sodium hydroxide to adjust the pH value to 7-8, leave overnight, filter , The filtrate is decompressed to recover ethanol, that is, too.

Embodiment 3

[0072] The tablet preparation of embodiment 3 medicines of the present invention

[0073] Lobelia 100g Almond 50g Pinellia 45g Aristolochia 200g

[0074] Scutellaria baicalensis 400g Ginkgo fruit 50g Astragalus 180g Aster 200g

[0075] Yangjinhua 40g Schisandra 40g

[0076] The preparation method is as follows:

[0077] Wash the raw materials Lobelia, Almond, Pinellia, Aristolochia, Scutellaria, Ginkgo, Astragalus, Aster, Dajinhua and Schisandra, add water to decoct twice, the amount of water added each time should not cover the surface of the medicine, For 2 hours each time, combine the decoctions, filter, concentrate and let cool; add three times the amount of 95% ethanol, leave overnight, filter; add 40% sodium hydroxide to adjust the pH value to 7-8, leave overnight, filter, and decompress the filtrate Recover ethanol, spray dry, add volatile oil clathrate to the medicinal powder, make granules with 90% alcohol as wetting agent, spray dry at 40°C-50°C, size the granules...

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Abstract

Disclosed is a Chinese medicinal prescription for treating asthma and bronchitis, which is prepared from radical lobelia, apricot seeds, pinellia tuber, baikal skullcap root, gingko, astragalus root, aster, datura flower and schisandra fruit by a predetermined weight proportions, and can be prepared into any of the conventional oral administration dosage forms.

Description

Technical field: [0001] The invention belongs to the field of traditional Chinese medicines, in particular to a medicine for treating asthma and acute and chronic bronchitis and a preparation method thereof. Background technique: [0002] At present, Western medicine for the treatment of asthma is mainly to control acute attacks, including adrenaline, theophylline, anticholinergics, glucocorticoids and other drugs used alone or in combination to achieve the purpose of rapidly relieving bronchospasm. Chronic bronchitis The treatment of acute attack and chronic protracted stage is mainly anti-infection, expectorant, and antitussive. When accompanied by wheezing, the same drugs as bronchial asthma can be used to obtain better clinical efficacy, but long-term use of the above drugs is prone to serious complications . Due to the complex etiology of asthma and large individual differences, many clinically effective prescriptions such as "Dingchuan Decoction", "Mahuang Decoction" ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8888A61K36/81A61K36/736A61K36/57A61K36/539A61K36/481A61K36/34A61K36/28A61K36/264A61K36/16A61K9/02A61K9/08A61K9/10A61K9/16A61K9/46A61P11/00
Inventor 王志岐
Owner 王志岐
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