Remedy for corneal failure

A technology of cornea and corneal sensitivity, applied in sensory diseases, nervous system diseases, peptide/protein components, etc., can solve problems such as not found
CN100413538CInactive Publication Date: 2008-08-27SENJU PHARMA CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
SENJU PHARMA CO LTD
Publication Date
2008-08-27
Estimated Expiration
Not applicable · inactive patent

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Abstract

It is intended to provide a drug of a novel type for restoring the corneal sense after keratotomy or improving the dry eye symptom. Application of a somatostatin receptor agonist is useful in improving corneal dysesthesia following cataract operation, following LASIK operation, or associating corneal nerve degeneration such as neuroparalytic keratitis, corneal ulcer or diabetic keratopathy, and the dry eye symptom.
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Description

technical field

[0001] The present invention relates to a corneal nerve axon extension promoter comprising a somatostatin receptor antagonist, and a corneal nerve axon-based extension for restoring or improving corneal sensitivity or treating dry eye or corneal Agents for epithelial defects. Background technique

[0002] Since the corneal nerve is severed by corneal surgical procedures such as laser photorefractive keratotomy (PRK), laser-assisted in situ keratectomy (LASIK), keratoplasty, etc., corneal sensitivity is said to usually decrease for about 3 weeks to 1 year. As a result of reduced function of corneal sensitivity, patients blink less frequently after corneal surgery, problematically exhibiting symptoms of dry eye. In dry eye patients, lacrimal hypofunction produces corneal hyposensitivity, which, in combination with additional lacrimal hypofunction, may exacerbate corneal surface disorders. However, currently restoration of corneal sensitivity after corneal sur...

Claims

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