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Microporous structure blood vessel stent

A vascular stent and microporous structure technology, applied in stents, medical science, prostheses, etc., can solve the problems of limited drug loading, stenosis, and uncontrollable drug release rate.

Inactive Publication Date: 2009-03-25
SOUTHEAST UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, most of the existing drug-coated stents are drug-coated on the surface of ordinary bare stents. The stent design does not fully consider the characteristics of drug loading, so its structure has uncontrollable drug release rate. At the same time, because the stent-coated surface can only cover 5-12% of the intimal surface of the blood vessel, so its drug loading is limited, and about 10% of restenosis occurs

Method used

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  • Microporous structure blood vessel stent
  • Microporous structure blood vessel stent
  • Microporous structure blood vessel stent

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Example 1: See Figure 5 As shown, a vascular stent with a microporous structure is composed of metal microtubes carved into a network tube structure by laser. The network tube structure is formed by connecting 8 groups of support rings 10 through connecting curved rods. Each group of support rings 10 is composed of 6 unit waves 11, and the unit waves 11 are composed of a straight section of candied haws alternately biased rods 14 and double ears. The offset hole-shaped arc segment 18 is composed of three connecting curved rods between adjacent support rings 10, and the connecting curved rods are straight micro-holes 21, and the connecting curved rods are evenly arranged in the circumferential direction.

Embodiment 2

[0026] Example 2: See Figure 6 As shown, a vascular stent with a microporous structure is composed of metal microtubes carved into a network tube structure by laser. The network management structure is composed of 10 groups of support rings 10 connected by connecting curved rods. Each group of support rings 10 is composed of 8 unit waves 11, and the unit waves 11 are composed of a straight section of the candied gourd symmetrical rod 12 and a single-hole central type. The circular arc section 15 is composed of four connecting curved rods between adjacent support rings 10, the connecting curved rods are arc-segment micro-holes 22, and the connecting curved rods are evenly arranged in the circumferential direction.

[0027] Carve the microporous structure on the support rod of the stent and the connecting curved rod. Secondly, make the material near the micropore without reducing the mechanical properties of the material, and this structure will not deform when the stent is crimped ...

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Abstract

The present invention relates to a blood vessel support with micro pore structure. It has a reticular structure made of metal micro tube graven by laser, and the described reticular structure is characterized by that it is formed from several groups of micro pore supporting rings which are connected by means of micro pore connection curved bars, the described every group of micro pore supporting rings is formed from 4-16 unit waves, and adjacent two micro pore supporting rings are connected by adopting 2-16 micro pore connection curved bars, and the described unit wave is formed from flat straight part and curved part. Said micro pore structure support can be favorable for loading medicine, can raise medicine-loaded quantity; and is easy to control and release.

Description

Technical field [0001] The invention relates to an expandable blood vessel stent used for percutaneous puncture angioplasty to treat blood vessel obstruction. Specifically, it relates to a microporous blood vessel stent combined with a microporous support ring and a microporous connecting curved rod, which belongs to the technical field of medical device manufacturing. Background technique [0002] After successful percutaneous transluminalcoronary angioplasty (PTCA), 30-50% of restenosis still occurs within 3 to 6 months after the operation, and the occurrence of restenosis has become the field of minimally invasive interventional treatment of cardiovascular diseases Interesting research hotspots. [0003] With the in-depth study of the mechanism of restenosis, it has been found that the proliferation of smooth muscle cells, thrombosis and vascular wall remodeling caused by vascular wall damage caused by minimally invasive interventional therapy are the three main causes of rest...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61F2/90A61M29/00A61L27/06A61F2/91
CPCA61F2250/0068
Inventor 倪中华顾兴中易红汤文成王跃轩
Owner SOUTHEAST UNIV