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Wound closing device containing erucic acid

A closure device and erucic acid technology, applied in medical science, surgery, etc., can solve problems such as sticking to death that cannot be pulled apart, destroying the appearance of human skin, increasing patient pain, etc., to inhibit the invasion of bacteria, facilitate rapid healing, and avoid infection inflammatory effect

Inactive Publication Date: 2009-06-03
NANJING TECH UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] 1. The suture and ligation process delays the operation time
[0004] 2. Permanent scars will be left after the sutures are removed, destroying the beauty of human skin
[0005] 3. The suture thread entering the subcutaneous tissue will cause rejection of the human body and easily cause inflammation and infection of the wound
[0006] 4. The process of suturing and removing stitches will increase the pain of the patient, and needles and thread ends are easy to enter the wound by mistake, posing hidden dangers
[0007] 5. Due to the inevitable slight bleeding after the operation, the part where the operation site and the medical zipper tooth row are combined will appear adhesion
However, the zipper of ordinary fabric is still used, which is still easy to cause wound allergies
In addition, all relevant inventions do not involve the anti-adhesion protective agent containing erucic acid, which often leads to the following situations: after the operation, the wound surface and other serosas will quickly produce adhesions, generally within 24 hours. Physiological adhesions can occur, while It takes 5-7 days for mesothelial cells to cover organ wounds to achieve physiological repair or peritoneal re-epithelialization; at the same time, after the zipper is opened, a small amount of blood seeped from the surgical site will adhere to the teeth and cause adhesions, making the The zipper is difficult to open again or is completely stuck and cannot be opened

Method used

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  • Wound closing device containing erucic acid
  • Wound closing device containing erucic acid
  • Wound closing device containing erucic acid

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] Heat and melt 50 g of erucic acid and mix it with 0.5 g of tea tree oil, add 20 g of glycerin, 20 g of zinc oxide and 10 g of starch, grind it into an ointment, make an anti-adhesion protective agent, and apply it to the support pad (9) and the support belt (1 ) inside, made of anti-blocking protective agent coating.

[0037] Such as figure 1 , 2 As shown, the present invention includes a zipper (5) composed of a mosaic tooth row (2) placed on the support belt (1) and a zipper puller (3), and the support belt (1) is provided with an excretion opening (6) , the two ends of the zipper (5) have pull-ring belts (4), the two sides of the support belt (1) are connected with the flexible connecting belt (7) and the support pad (9) through double-sided adhesive, and the skin adhesive belt (8) is pasted Adhesive strips (10) are arranged, and the inner side of the support pad (9) and the support belt (1) is coated with an anti-blocking protective agent coating (12) containing e...

Embodiment 2

[0041] Except that the formula of the anti-adhesion protective agent is modified to: 54g of erucic acid, 0.4g of tea tree oil, 15g of glycerin, 10g of zinc oxide and 17g of starch, the others are the same as in Example 1.

Embodiment 3

[0043] Except that the formula of the anti-adhesion protective agent is modified to: erucic acid 46g, tea tree oil 0.8g, glycerin 24g, zinc oxide 15g and starch 20g, others are the same as Example 1.

[0044] Biocompatibility studies

[0045]In this study, according to the use of medical zippers, the skin irritation test was carried out to evaluate its biocompatibility with reference to the national standard medical device biological evaluation.

[0046] 1 Experimental materials

[0047] The medical zipper obtained in embodiment 1

[0048] 20 ordinary grade New Zealand rabbits were provided by the Experimental Animal Center of China Pharmaceutical University. Feed full-price nutritious pellet feed, eat food at will, drink water constantly, and maintain good cleanliness and sanitation.

[0049] 2 Skin irritation test method

[0050] Adult healthy New Zealand rabbits, both male and female, weighing 1.5-2.5kg, the skin of the animal is depilated 24 hours before administration...

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Abstract

The invention relates to a wound closing device, especially a surgery wound closing chaining of the anti-paste protectant containing the rap oil foot extract erucic acid which is made of antibiotic material hemp. The invention can avoid the surgery sewing process and can not cause any sewing wound. The anti-paste protectant containing the erucic acid has the characteristic of high boiling point, uneasy to volatile and decompose, slow absorption, which can prevent the conglutination of the wound and the chaining when being painted at the lower part of the chaining, and is favourable for the fast heal of the wound, and free from infection, and can be opened at anytime to see the healing condition.

Description

technical field [0001] The invention relates to a wound closure device, in particular to an anti-adhesion protective agent containing erucic acid extracted from rapeseed oil feet, and a zipper for surgical wound closure made of antibacterial material hemp fiber. Background technique [0002] When dealing with the skin wound that surgical operation forms, the method commonly used in each hospital of my country is to suture with medical suture thread or to use common medical zipper. But this method has the following defects: [0003] 1. The suturing and ligation process delayed the operation time. [0004] 2. Permanent scars will be left behind after stitches are removed, which destroys the beauty of human skin. [0005] 3. The suture thread entering the subcutaneous tissue will cause rejection of the human body and easily cause inflammation and infection of the wound. [0006] 4. The suturing and stitch removal process will increase the pain of the patient, and needles and...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61B17/03
Inventor 于文涛黄和张琪高振孙鹏何皓
Owner NANJING TECH UNIV