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Extraction method of antibacterial and antidiarrhea active compound in rubus corchorifolius leaf, extractive and use thereof

An extraction method and anti-diarrhea technology, applied in the direction of medical preparations containing active ingredients, antibacterial drugs, drug combinations, etc., can solve the problems of large toxic side effects and high prices, and achieve the effect of broad market prospects

Inactive Publication Date: 2007-08-15
曹庸
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AI Technical Summary

Problems solved by technology

[0005] The purpose of the present invention is to provide a method for extracting antibacterial and antidiarrheal active substances from natural plants, the extract extracted according to the method and the purposes of the extract, which can overcome the toxicity of artificially synthesized antibiotics and western medicine preparations. Disadvantages of large side effects and high price

Method used

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Examples

Experimental program
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Effect test

Embodiment Construction

[0023] (1) Extraction, separation and purification of antibacterial and antidiarrheal components of raspberry leaves

[0024] 1. The method for extracting the antibacterial and antidiarrheal components of raspberry leaves, the concrete steps are:

[0025] (1) dry the raspberry leaves collected in the shade indoors, and grind them into coarse powder through a 20-mesh sieve;

[0026] (2) Weigh 2500g raspberry leaf dry powder, add 10 times the volume of 80% ethanol, centrifuge after leaching at room temperature for 48 hours, take its supernatant, add 8 times the volume of 80% ethanol to repeat the extraction once, after centrifugation Merge the centrifugate, which is the raspberry leaf crude extract;

[0027] (3) Concentrate the crude extract by rotary evaporation at 50° C. and 0.09 MPa to obtain about 500 ml of a concentrate.

[0028] 2. Extraction and separation method of raspberry leaf extract. In the present invention, three different solvents are respectively tested for e...

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Abstract

The invention discloses Rubus corchorifolius extract with antibacterial and antidiarrheal effects, and its method and application. The method comprises drying and crushing leaves of Rubus corchorifolius, extracting with ethanol, filtering, mixing the filtrates, concentrating, separating with a solvent having moderate polarity, concentrating, and drying. This extract with good antibacterial and antidiarrheal effects can be used to produce antibacterial drug, and antidiarrheal drug exhibiting inhibitory effects on intestinal peristalsis in vitro. As compared with the prior arts, the invention has the advantages of less toxic and adverse side effects and low cost.

Description

technical field [0001] The present invention relates to the extraction of plant medicinal components, in particular, it provides a method for extracting antibacterial and antidiarrheal active components from raspberry leaves, an extract and the effect of the extract. Background technique [0002] Raspberry (Rubus corchorifolius L.f) with antibacterial and antidiarrheal effects is a deciduous shrub in the Rosaceae Rubus genus. It is distributed all over the country except Northeast China, Gansu, Xinjiang, and Tibet. It is widely distributed in the mountainous areas of western Hunan. The resource reserves are quite large, and its fruits, roots and stems can be used as medicine, which has the effects of eliminating food and fullness, stomach pain, bruises, and yellow water sores. The root has the effect of dispelling wind-dampness, and according to "Compendium of Materia Medica" records its fruit, root and leaf are used as medicine to have the effect of promoting blood circulat...

Claims

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Application Information

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IPC IPC(8): A61K36/73A61P1/12A61P31/04A61K127/00
Inventor 曹庸杜方鹿廖博儒
Owner 曹庸
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