Shenghong heat-clearing granule and its preparation method

Abstract

The invention discloses a Shenghongqingre granule and its producing method which is produced by following material by weight: Ageratum conyzoides, forsythia suspensa, herba bidentis pilosae, Hongmuxiang; the producing method is: extracting above four drugs twice in water to get extract, collecting volatile oil; filtering the extract, concentrating to dense cream, spray drying, producing to granule with proper amount of cane sugar and dextrin, straightening granulating, injecting all of collected volatile oil, producing granule containing sugar; or concentrating the extract to dense cream, spray drying, mixing with proper amount of dextrin and stevio to form granule, straightening granulating, injecting all of collected volatile oil, producing granule not containing cane sugar. The invention only extracts effective components, removing other non-drug components, meanwhile the extracting process can kill the infected microbe of the crude drugs with additive production steps. The invention has a high concentration of effective component, a good curative effect and a simple craft.

Description

Technical field: [0001] The invention relates to a pure traditional Chinese medicine preparation, in particular to a Shenghong Qingre granule with functions of clearing heat and detoxifying, regulating qi and relieving pain, dispelling blood stasis and dispelling stagnation, which is used for treating damp-heat injection, qi stagnation and blood stasis, and chronic pelvic inflammatory disease, and also relates to a preparation method . Background technique: [0002] Shenghong Qingre Granules are prepared from four herbs: Shenghong Ji, Forsythia, Trifoliate Ghost Needle, and Hongmuxiang, and mainly contain sugar, alkaloids, and volatile oils. A large number of sugar components make it easy to absorb moisture, and the moisture exceeds the standard, which also has a great impact on the dissolution of the drug. It must be strictly monitored during the production process of the drug. In addition, the choice of dosage form also has a great impact; at the same time, the traditional...

AI Technical Summary

Problems solved by technology

[0018] The above-mentioned preparation method mixes the ointment and part of the crushed powder of thistle to make granules, and the raw powder of the medicinal material also contains other non-medicinal ingredients, and the active ingredients of the prepared medicine cannot be fully dissolved, which reduces the efficacy of the medicine and cannot play the best role. treatment effect

In addition, when comparing different solid dosage forms, most of the other dosage forms are swallowed directly. For the convenience of taking, the dosage is limited. The preparation process used is to facilitate the preparation and ensure the properties of the drug. It is not conducive to drug absorption. On the other hand, the raw powder of medicinal materials is prone to microorganisms. To kill microorganisms, additional sterilization steps are required, which makes the production process complicated.

[0019] In addition, the traditional granule preparation process uses a drying method to dry the clear paste into a block dry paste, and then crush it into a fine powder. The drying speed is slow, the efficiency is low, the process is tedious, the time is long, and the fine powder is not uniform after crushing. , it is easy to cause the prepared particles to have coke after melting