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Processing method for biological pharmacy waste residue

A treatment method, biopharmaceutical technology, applied in the field of biopharmaceutical waste residue treatment, to achieve the effects of shortening drying time, reducing nutrient loss, and increasing processing capacity

Active Publication Date: 2011-05-11
上海拜森生物技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The technical problem to be solved by the present invention is to provide a treatment method for biopharmaceutical waste residues, to solve the existing biopharmaceutical waste residue treatment problems, use the treatment method of the present invention to quickly achieve the drying of pharmaceutical waste residues, improve the utilization value of pharmaceutical waste residues, and reduce environmental pollution

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] Take 1000g of pharmaceutical waste residue and dry it for 3 hours under the condition of vacuum degree of 3000Pa and microwave power of 267W until the water content of the dry waste residue is 10%.

[0015] Get 50g of pharmaceutical waste residue with a water content of 10% as a substrate, add 295ml of tap water to make the pharmaceutical waste residue substrate concentration 15%, then stir evenly, adjust the pH to 7.0 with sodium hydroxide solution, heat up to 50°C and add papain (the activity is 300,000 units) and neutral protease (the activity is 50,000 units) to make 5g of compound enzyme by weight ratio of 1:5, keep it warm for 8 hours, then raise the temperature to 70°C, keep it warm for 15 minutes to kill the enzyme , the enzymatic hydrolysis rate reaches 70%. After the enzyme is eliminated, the enzymatic hydrolysis solution is separated from the residue. The enzymatic hydrolysis solution produces polypeptide and amino acid products, and the enzyme residue is dri...

Embodiment 2

[0017] Take 1000g of pharmaceutical waste residue and dry it for 7 hours under the condition of vacuum degree of 2500Pa and microwave power of 160W until the water content of the dry waste residue is 12%.

[0018] Get 100g water content and be the pharmaceutical waste residue of 12%, add tap water 721ml to make the waste residue substrate concentration be 12%, stir then, pH is adjusted to 7.2 with sodium hydroxide solution, be warming up to 52 ℃ and add by papain (activity is 30 10,000 units) and neutral protease (the activity is 50,000 units) are made into 7.7g of compound enzyme by 1:5 weight ratio, keep warm for 6 hours, then raise the temperature to 72 ℃, keep warm for 12 minutes to kill the enzyme, the enzymolysis rate After reaching 65%, the enzymatic hydrolysis solution is separated from the residue after the end of the enzyme inactivation. The enzymatic hydrolysis solution produces polypeptide and amino acid products, and the enzyme residue is dried as flower nutrient ...

Embodiment 3

[0020] Take 1000g of pharmaceutical waste residue and dry it for 5 hours under the condition of vacuum degree of 2000Pa and microwave power of 350W until the water content of the dry waste residue is 8%.

[0021] Get 50g water content and be 8% pharmaceutical waste residue, add tap water 452ml and make substrate concentration be 10%, stir then, pH is adjusted to 7.5 with sodium hydroxide solution, be warming up to 55 ℃, add by papain (activity is 30 10,000 units) and neutral protease (activity is 50,000 units) compound enzyme 3g that is made into through 1:5 weight ratio, keep warm for 10 hours, then raise the temperature to 75 ℃, keep warm for 10 minutes to kill enzyme, enzymolysis rate After reaching 60%, the enzymatic hydrolysis solution is separated from the residue after the enzyme inactivation is completed. The enzymatic hydrolysis solution produces polypeptide and amino acid products, and the enzyme residue is dried as flower nutrient soil.

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PUM

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Abstract

The present invention discloses decoction dregs treating biological process. The process includes the following steps: 1. microwave drying decoction dregs to water content of 8-12 wt%; 2 enzymolyzing the dried decoction dregs with composite protease comprising papain and neutral protease; 3. deactivating enzyme at 70-75 deg.c for 10-15 min to obtain enzymolyzed liquid; and 4. processing the enzymolyzed liquid into polypeptide and amino acid product, and drying the enzymolysis residue into flower nourishing soil. The present invention raises the utilization value of decoction dregs and reducesenvironmental pollution.

Description

technical field [0001] The invention relates to a treatment method for pharmaceutical waste residue, in particular to a treatment method for biopharmaceutical waste residue. Background technique [0002] At present, my country's biopharmaceutical industry is developing rapidly and has a good prospect, but the pollution accompanying the development is also becoming more and more serious. How to effectively treat and utilize biopharmaceutical waste residues is of great significance to saving resources, preventing environmental pollution, and developing circular economy. The pharmaceutical waste produced by microbial fermentation is rich in protein, polysaccharides and minerals. Pharmaceutical waste residue is generally a viscous material with high water content. Because it is rich in mycelium, organic and inorganic substances, it is easy to breed bacteria, spoil and deteriorate, and produce foul smell. If the water content of the pharmaceutical waste residue is lower than 15...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): B09B3/00C12P21/00C12P13/00
Inventor 吴奇能雷耀霞汪红兵余世贤
Owner 上海拜森生物技术有限公司