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A biosensor, optical fiber technology, applied in biological testing, fluorescence/phosphorescence, instruments, etc., can solve the problems of patent achievement reporting, and achieve the effects of good selectivity, easy operation and portability
Inactive Publication Date: 2007-12-05
DALIAN MARITIME UNIVERSITY
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[0029] The Y-shaped optical fiber bundle 9 used in the optical fiber fluorescent biosensor is formed by bundling seven multi-film optical fibers, one in the center and six in total around. As shown in Figure 2, at one end of the Y-shaped fiber bundle 9, the central optical fiber separates from the fiber bundle 9 and forms a branch of the Y-shaped fiber bundle 9, i.e. a branch 10; other peripheral optical fibers are bundled to form the Y-shaped fiber bundle 9 The other branch is the branch 11; the other end of the Y-shaped optical fiber bundle 9 is used as the third branch of the Y-shaped optical fiber bundle 9, namely the branch 12.
[0030] The branch 10 of the Y-shaped fiber bundle 9 is composed of a single multi-film optical fiber 13 in the center of the Y-shaped fiber bundle 9, and its cross-sectional schematic diagram is shown in FIG. 3 . The inner layer of the central multi-film optical fiber 13 is the core 14, and its material is high-purity silicon oxide. The outer la...
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Abstract
The invention discloses a fibre-optical fluorescent biological sensor, which comprises the following parts: optical exciting path, optical detecting path and fluorescent receiving optical path, wherein three optical paths are connected on three branches of Y-shaped optical fiber; the optical exciting source utilizes the coupling light to couple on one branch of Y-shaped optical fiber on the optical exciting path; another branch of Y-shaped optical fiber is used to fix biological identifier, which is connected with the carrier or sample pond; the third branch of Y-shaped optical fiber is connected with the data gathering system, which is connected with signal disposing and display system further. The invention possesses rapid response, high sensitivity, good selectivity, light weight, small bulk and good friend biological property, which is fit for all fluorescent markers in the biological molecular identifying, medical clinical diagnosis, high-flux drug sieving, environment monitoring, and biochemical agent detecting domain.
Description
technical field [0001] The invention relates to an optical fiber fluorescent biosensor, which can be widely used in many fields such as medical diagnosis, biomolecules, drug screening, environmental monitoring, food sanitation detection, biochemical warfare agent detection and the like. Background technique [0002] A sensor is a component that can sense a certain signal to be measured and convert it into sound, light, electricity and other signals, including sensitive components, conversion components and corresponding circuits. There are many types of sensors, among which the sensors composed of biological materials such as antigens, antibodies, enzymes, nucleic acids, cells, etc. , FOBS), this sensor determines the amount of the substance to be tested by detecting the light generated by the biological reaction, and by detecting the wavelength, intensity, amplitude, phase and other parameters of the light. Compared with other sensors, this sensor has the advantages of str...
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