Anti-wrinkle agent

An accelerator, watercress technology, applied in the field of skin relaxation and skin elasticity improvement, artificial skin manufacturing, can solve problems such as low skin function, increase skin viscoelasticity, reduce skin moisture evaporation, and improve the effect of loosening

Active Publication Date: 2008-04-02
SHISEIDO CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition to their various constituent characteristics, it is known that the basement membrane itself will also appear multilayered, decomposed and fractured with skin aging (lavker et al., J.Invest.Dermatol.1979 73:59-66 ), and it is believed that the result of this structural change is the appearance of aging characteristics such as wrinkles, sagging, and the reduced skin function that accompanies aging

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0183] Example 1 - Cream

[0184] (1) Prescription

[0185] (Phase A)

[0186] Stearic acid 10.0% by weight

[0187] Stearyl Alcohol 4.0

[0188] Butyl stearate 8.0

[0189] Monoglyceride Stearate 2.0

[0190] Vitamin E Acetate 0.5

[0191] Vitamin A Palmitate 0.1

[0192] Macadamia Oil 1.0

[0193] Appropriate amount of preservatives

[0194] Appropriate amount of spices

[0195] (phase B)

[0196] Glycerin 4.0

[0197] 1,2-pentanediol 3.0

[0198] Potassium hydroxide 0.4

[0199] Magnesium Ascorbyl Phosphate 0.1

[0200] L-arginine hydrochloride 0.01

[0201] Trisodium EDTA 0.05

[0202] Watercress 1,3-butanediol extract 0.5

[0203] Ion-exchanged water Others

[0204] (2) Manufacturing method

[0205] The oil phase part of A and the water phase part of B were heated at 70° C. until completely dissolved. Add phase A to phase B and emulsify with emulsification equipment. The emulsion was cooled with a heat exchanger.

Embodiment 2

[0206] Example 2 - Cream

[0207] (1) Prescription

[0208] Stearic acid 5.0% by weight

[0209] Stearyl Alcohol 4.0

[0210] Isopropyl myristate 18.0

[0211]Glyceryl Monostearate 3.0

[0212] Propylene glycol 10.0

[0213] Methanol extract of juniper 0.01

[0214] Caustic potash 0.2

[0215] Sodium bisulfite 0.01

[0216] Appropriate amount of preservatives

[0217] Appropriate amount of spices

[0218] Ion-exchanged water balance

[0219] (2) Manufacturing method

[0220] Add propylene glycol, juniper methanol extract and caustic potash into ion-exchanged water, dissolve, heat, and keep warm at 70° C. (water phase). Mix other ingredients and heat to dissolve, keep warm at 70°C (oil phase). Slowly add the oil phase to the water phase, and after all the addition, place it at this temperature for a period of time to allow it to react. Then, perform homogeneous emulsification with a homogenizer, and cool to 30° C. while fully stirring.

Embodiment 3

[0221] Example 3 - Anti-Wrinkle Cream

[0222] (1) Prescription

[0223] Stearic acid 2.0% by weight

[0224] Stearyl Alcohol 7.0

[0225] Hydrogenated Lanolin 2.0

[0226] Squalane 5.0

[0227] 2-Octyldodecanol 6.0

[0228] Polyoxyethylene (25 moles) cetyl ether 3.0

[0229] Glyceryl Monostearate 2.0

[0230] Propylene Glycol 5.0

[0231] Atractylodes ethanol extract 0.05

[0232] Ethanolic extract of turmeric 0.05

[0233] Sodium bisulfite 0.03

[0234] Ethyl p-hydroxybenzoate 0.3

[0235] Appropriate amount of spices

[0236] Ion-exchanged water balance

[0237] (2) Manufacturing method

[0238] Add propylene glycol to ion-exchanged water, heat, and keep warm at 70° C. (water phase). Mix other ingredients, heat to dissolve, and keep warm at 70°C (oil phase). Slowly add the oil phase into the water phase to carry out preliminary emulsification reaction, carry out homogeneous emulsification with a homogenizer, and cool to 30°C while fully stirring.

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PUM

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Abstract

The present invention provides a novel anti-wrinkle agent containing at least one of extracts of watercress, juniper, Atractylodes macrocephala and coltsfoot as an active ingredient.

Description

technical field [0001] The present invention relates to a novel anti-wrinkle agent. More specifically, the present invention relates to an anti-wrinkle agent containing watercress, juniper, Atractylodes macrocephala and / or coltsfoot-derived extracts as active ingredients. In addition, the present invention also relates to a basement membrane stabilizer, an extracellular matrix production accelerator, and an agent for improving skin laxity and skin elasticity, which use the above-mentioned extract as an active ingredient, as well as a method for manufacturing artificial skin using the above-mentioned extract, and a method for reducing wrinkles, A method for improving sagging skin and skin elasticity. Background technique [0002] The skin that covers the entire body of various animals including humans undergoes changes such as wrinkle formation, hardening, and pigmentation due to external factors such as sunlight, dryness, oxidation, stress from environmental factors, and me...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/97A61Q19/00A61K36/00A61K36/18A61K36/28A61P17/00A61Q19/08A61L27/00
CPCA61K8/97A61Q19/08A61K8/9789A61P17/00
Inventor 高田惠子猪股慎二小仓有纪海盐健一
Owner SHISEIDO CO LTD
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