Beta-Lacetam anti-biotic compound dose for animal containing benemid

Abstract

The invention relates to a Beta-lactam antibiotic compound preparation for animals, which contains probenecid. Calculated by weight percentage, the preparation is composed of 1 to 20 percent of probenecid , 5 to 20 percent of Beta-lactam antibiotic, 5 to 40 percent of cosolvent, and acceptable vector in pharmacy which is added until the preparation is 100 percent. The preparation can be orally administrated , and can be dissolved in water to be drunk by livestock and fowl. The invention has a broad antifungal spectrum, shows a strong antibacterial activity, is convenient to be used clinically, has good safety, and is applicable to treating light to moderate infection. The used practice shows that the preparation can reduce the dosage of the Beta-lactam antibiotic in clinical practice, can reduce the occurrence possibilities of drug resistance, and can also save the treatment cost with good using effect.

Description

Technical field [0001] The invention relates to a veterinary β-lactam antibiotic preparation, in particular to a veterinary β-lactam antibiotic compound preparation containing probenecid. Background technique [0002] Beta-lactam antibiotics are commonly used antibiotics, not only used in humans, but also in the treatment of animal diseases. They play a bactericidal effect by inhibiting the biosynthesis of cell wall mucopeptides during the active reproduction stage of bacteria. Its characteristics It is easy to be absorbed by oral administration, has a broad antibacterial spectrum, obvious antibacterial effect, and a definite curative effect. However, the blood concentration of β-lactam antibiotics is maintained for a short time and needs to be administered frequently during use. This will not only increase the amount of treatment and increase the cost of treatment. Moreover, when used as a veterinary drug, frequent administration will also increase a lot of work for the operator...

AI Technical Summary

Problems solved by technology

[0002] β-lactam antibiotics are commonly used antibiotics, not only for humans, but also for the treatment of animal diseases. They play a bactericidal effect by inhibiting the biosynthesis of cell wall mucopeptides during the active reproduction stage of bacteria. Their characteristics It is easy to absorb when taken orally, has a wide antibacterial spectrum, obvious antibacterial effect, and definite curative effect, but the blood concentration of β-lactam antibiotics is maintained for a short time, and frequent administration is required during use, which will not only increase the amount of treatment and increase treatment costs. Moreover, when used as a veterinary drug, frequent administration will increase the workload of the operator, so a drug that can delay the excretion of β-lactam antibiotics is sought to prolong the action time of β-lactam antibiotics in animals and reduce The frequency of administration has become the direction of our research on the application of β-lactam antibiotics