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Chick-pea embryo and bean sprout valid part, preparing method and application thereof

A technology for effective parts and chickpeas, which is applied to the effective parts of chickpea germs and bean sprouts and the fields of their preparation and application, and can solve problems such as differences in the percentage of blood sugar drop.

Active Publication Date: 2008-06-18
XINJIANG TECHN INST OF PHYSICS & CHEM CHINESE ACAD OF SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The study adopted the method of intragastric administration, and found that the chickpea bean sprouts extract had a significant hypoglycemic effect on alloxan hyperglycemia model mice. Although the model group animals gradually decreased their blood sugar over time, the blood sugar levels of the administration group There is a very significant difference between the percentage reduction and its comparison

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] Embodiment 1 (alcoholic extract)

[0036] Germinate chickpeas by conventional means;

[0037] Wash the selected chickpea raw materials and put them into the container. The top of the container is required to have a washing device, and the bottom edge should leave a hole with a diameter of 5 cm and a vent hole, and then add water for soaking, so as to facilitate it. For germination, usually soak for 2 hours to ensure that the raw beans can absorb enough water. After soaking, the raw beans that have absorbed enough water are poured with water every 5 hours at room temperature. When the bean sprouts grow to 6cm long, the longest does not exceed 10cm;

[0038] Preparation of chickpea germ and bean sprout alcohol extract:

[0039] Sieve the dried chickpea germ and bean sprout powder to 25 meshes, place 5 grams each in a round bottom flask, add 2 times volume concentration of 10% methanol, take 15 times with ultrasonic waves, each time for 1 hour, filter with filter paper, ...

Embodiment 2

[0040] Embodiment 2 (water extract)

[0041] Germinate chickpeas in the usual way;

[0042] Wash the selected chickpea raw materials and put them into the container. The top of the container is required to have a washing device, and the bottom edge should leave a water hole with a diameter of 6 cm and a ventilation hole, and then add water for soaking, so as to facilitate it. For germination, usually soak for 3 hours to ensure that the raw beans can absorb enough water. After soaking the raw beans that have absorbed enough water, pour water every 6 hours at room temperature. When the bean sprouts grow to 7cm long, the longest does not exceed 10cm;

[0043] Preparation of aqueous extracts of chickpea germ and bean sprouts:

[0044] Sieve the dried chickpea germ powder and bean sprout powder to 25 meshes, place 5 grams each in a round-bottomed flask, add 2 times the volume of pure water, extract 15 times with ultrasonic waves, each time for 2 hours, and use gauze and filter pa...

Embodiment 3

[0052] Embodiment 3 (alcoholic extract)

[0053] Germinate chickpeas in the usual way;

[0054] Wash the selected chickpea raw materials and put them into the container. The top of the container is required to have a washing device, and the bottom edge should leave a hole with a diameter of 5.5 cm and a vent hole, and then add water for soaking, so as to facilitate Its germination, usually soaked for 2.5 hours, can ensure that the raw beans can absorb enough water. The raw beans that have absorbed enough water after soaking are poured with water every 5.5 hours at room temperature. When the bean sprouts grow to 8cm long, it is enough. No more than 10cm in length;

[0055] Preparation of Alcohol Extract from Chickpea Germ and Bean Sprout

[0056] Cut the chickpea germ and bean sprouts into sections, each section is about 2 mm long, put 5 grams each in a round bottom flask, add 5 times the volume concentration of 50% ethanol, and extract 5 times with heating and reflux, 2 hour...

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PUM

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Abstract

The invention relates to a chickpea germ, effective part of bean sprout, a preparation method and application. The effective part of the total saponin and isoflavone can be obtained from the chickpea germ and bean sprout by adopting an alcohol extraction method or a water extraction method; the initial screening test of the effective part proves that: the effective part has the advantages of playing a role as an inhibitor for protein tyrosine phosphatase (PTP1B). The effective part can be used as a medicine for treating diabetes and as an application of health care product, simultaneously, the effective part or the derivative of which can be applied as a drug combination.

Description

technical field [0001] The invention relates to an effective part extracted from chickpea germ and bean sprouts or dried chickpea germ powder and bean sprout powder, and the effective part is used as preparation for treating hypoglycemia, especially for treating type 2 diabetes. Background technique [0002] Plant extract is a new industry, it has only been ten years since its appearance, but there has been a frenzy of "returning to nature" all over the world. Chinese herbal medicine produces a sense of security, which makes the development of plant extracts rapid and unstoppable. The plant extract market is closely related to the herbal drug market. In 2005, the global herbal drug market was 26 billion US dollars, of which Europe: 34.5% (Germany and France accounted for 65%), North America: 21%, Asia: 26%, Japan: 11.3%. The growth rate of the global herbal medicine market is 10% to 20%, and the growth rate of the global plant extract market is 15% to 20%. The main active...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/48A61P3/10A23L1/30A61K131/00
Inventor 阿吉尔克拜尔·艾萨程珍阿不力米提·伊力信学雷马庆玲高艳华
Owner XINJIANG TECHN INST OF PHYSICS & CHEM CHINESE ACAD OF SCI
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