Medicine compounds for treating diabetic nephropathy

A technology for diabetic nephropathy and a composition is applied in the field of pharmaceutical compositions for the treatment of diabetic nephropathy, which can solve problems such as unsatisfactory effects and inability to effectively inhibit the development of diabetic nephropathy, and achieve good therapeutic effects, synergistic effects, and complementary mechanisms.
CN101229373BActive Publication Date: 2010-09-15LUNAN PHARMA GROUP CORPORATION
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
LUNAN PHARMA GROUP CORPORATION
Publication Date
2010-09-15

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Abstract

The invention provides a novel medical composite for treating diabetic and nephropathy, which comprises insulin sensitizer and endothelin receptor blocker. The invention scientifically combines two medicines with complete different mechanisms of action so as to reach the target of mechanism complementation, mutual coordination, enhancement of treatment effect and rational usage of medicine. The novel medical composite for treating the diabetic and the nephropathy not only has good coordination in reducing blood sugar, but also achieves quite good coordination effect on protecting kidney. The novel medical composite for treating the diabetic and the nephropathy is probably a new breakthrough of the method for treating the diabetic nephropathy.
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Description

Technical field

[0001] The invention relates to a new pharmaceutical composition and its preparation for treating diabetic nephropathy. Background technique

[0002] Chronic complications of diabetes have gradually become the main disease that threatens the health of patients. Among them, diabetic nephropathy is one of the most serious chronic complications of diabetes; it is also one of the main causes of death in diabetic patients. According to reports, 50% of patients with type 1 diabetes died of chronic renal failure, while 5% to 10% of patients with type 2 diabetes died of renal failure.

[0003] With the increase of the incidence of diabetes, the number of DN patients is increasing day by day. Because of its hidden onset and slow progress, if it is allowed to develop, when persistent proteinuria appears clinically, the kidney disease is not in the early stage, and irreversible kidney disease has appeared. , It cannot be reversed with drugs, and so far there is no eff...

Claims

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