Method for measuring blood pressure, pulse and vas compliance without inserting vas cavity

A vascular compliance, internal measurement technology, applied in the measurement of pulse rate/heart rate, catheter, cardiac catheter, etc., can solve the problems of complex experimental operation, high requirements for anticoagulation, technical difficulty, etc., to achieve accurate blood pressure measurement, improve blood pressure The success rate, the effect of not easy to thrombosis

Inactive Publication Date: 2008-08-27
XI AN JIAOTONG UNIV
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Problems solved by technology

Its advantage is that it directly measures the intravascular pressure, eliminates the interference of anesthesia, surgery, and restraint, and can actually reflect the actual cardiovascular indicators of animals. The value is accurate and stable, and it can continuously ob

Method used

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  • Method for measuring blood pressure, pulse and vas compliance without inserting vas cavity
  • Method for measuring blood pressure, pulse and vas compliance without inserting vas cavity
  • Method for measuring blood pressure, pulse and vas compliance without inserting vas cavity

Examples

Experimental program
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Effect test

Embodiment 1

[0022] Embodiment 1, as shown in Figure 1, the subintimal implantation method diagram of the blood vessel: the blood vessel is clamped with an arterial clip, the blood flow is blocked, and the adventitia 3 of the blood vessel wall is cut longitudinally at the distal end of the blocked place, Separate the muscular layer 2, implant the probe 4 of the pressure transducer made of piezoresistor between the muscular layer 2 and the intima 1 of the blood vessel, seal and fix the output wire 5 of the pressure transducer with biological glue, and the pressure The output line 5 of the transducer transmits the piezoelectric signal to the amplifier, which is processed by a computer to continuously display changes in blood pressure and pulse (heart rate). The compliance of the blood vessel refers to the change value of the blood vessel volume when the pressure in the blood vessel changes by 1mmHg.

[0023] That is, C=ΔV / ΔP

[0024] In the formula, C is the compliance...

Embodiment 2

[0026]Embodiment 2: Referring to Fig. 2, blood vessel external sticking method: the probe 4 of the pressure transducer made of piezoresistor is closely attached to the adventitia 3 of the blood vessel, and then the probe 4 and the blood vessel 6 are fixed together in an inner diameter not larger than the blood flow. In the steel cylindrical sleeve 7 of blood vessel outer diameter when blocking. When the arterial clamp is released, the blood in the vessel lumen 8 is filled, the pressure increases, and the diameter of the elastic reservoir blood vessel increases with the increase of the arterial pressure, while the blood vessel at the piezoresistive probe 4 of the pressure transducer Because it is fixed in the cylindrical sleeve 7, the diameter of the blood vessel cannot change with the rise and fall of blood pressure, and the pressure in the blood vessel will be transmitted to the piezoresistor probe 4, causing a change in resistance, and the change in resistance is transmitted ...

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Abstract

A method for measuring blood pressure, pulse and vascular compliance without invading a vascular cavity is provided. The blood flow of a vessel is blocked by using an artery clamp, a voltage-variable resistor-containing probe of a pressure transducer is implanted between the muscle layer and the inner membrane of the vessel at the distal end to the heart, followed by biogum sealing; or the voltage-variable resistor probe is closely attached to the outer membrane of the vessel, and then the probe and the vessel are fixed together inside a rigid cylindrical cover. When the artery clamp is released, the pressure inside the vascular cavity rises and is transferred to the voltage-variable resistor probe, resulting in the change in resistance, the resistance change is converted into a current change that is processed by a computer to produce a continuously-recorded blood pressure change, and simultaneously the computer calculates pulses according to the peak distance of the blood pressure and records the change in pulse. The cylindrical cover is provided thereon with a tension transducer that converts a change of vessel displacement into a change of resistance and then a change of vessel displacement again, representative of the change in vascular volume, and calculates continuously-varying vascular compliance. The invention doesn't block the blood flow at the distal end of the vessel to avoid the influence on blood supply to the dominant organs of the vessel to be detected.

Description

technical field [0001] The invention relates to a method for measuring blood pressure, pulse and blood vessel compliance, in particular to a method for measuring blood pressure, pulse and blood vessel compliance without inserting into a blood vessel cavity. technical background [0002] Blood pressure and pulse (heart rate) are important vital indicators [0003] In biological science experiments and clinical practice, vital indicators are the basic monitoring items, among which blood pressure and heart rate are the most important observation indicators. For a long time, in animal experiments for blood pressure measurement, the main animals commonly used are: rats, rabbits, dogs, etc. Invasive blood pressure monitoring is widely used in animal experiments, and has become more and more widely used in clinics and operations. It can monitor blood pressure continuously, accurately and in time. For complex operations and clinical critical illnesses, it is helpful to judge the b...

Claims

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Application Information

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IPC IPC(8): A61B5/02A61B5/0215A61B5/024
Inventor 曹永孝孟新芳曹蕾刘静
Owner XI AN JIAOTONG UNIV
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