41results about How to "Less prone to thrombosis" patented technology

The present invention is specifically directed to a heart occlusion device with a self-centering mechanism. The heart occlusion device includes two separate uniquely shaped wires 12, 14, each forming shapes that mirror the respective wire's shapes. Each wire forms half-discs or quarter-discs that together form a distal disc and a proximal disc. In other versions, the device includes four separate wires, each mirroring its neighboring wire and forming a proximal and a distal quarter-disc. In the versions with four wires, the quarter-discs of each wire together form proximal and distal discs. The distal disc and proximal disc are separated by a self-centering waist. The proximal disc is attached to a hub comprising a screw mechanism. A similar hub is optional on the distal disc. The discs further include coverings which form a sealant to occlude an aperture in a tissue. The wires forming the discs have a shape-memory capability such that they can be collapsed and distorted in a catheter during delivery but resume and maintain their intended shape after delivery.

A method of coating implantable open lattice metallic stent prosthesis is disclosed which includes sequentially applying a plurality of relatively thin outer layers of a coating composition comprising a solvent mixture of uncured polymeric silicone material and crosslinker and finely divided biologically active species, possibly of controlled average particle size, to form a coating on each stent surface. The coatings are cured in situ and the coated, cured prosthesis are sterilized in a step that includes preferred pretreatment with argon gas plasma and exposure to gamma radiation electron beam, ethylene oxide, steam.

A peripheral stent with individual segments reduces the occurrence of fatigue fracture failure seen in vessels and tubes having bending and twisting movement. Segments can be attached via connecting fibers that biodegrade and offer the segments freedom of movement. The segments are balloon-expandable but will not be crushed by external forces placed upon the stent. Hinges and struts provide the stent with a plastic deformation during expansion and remain elastic if exposed to an oval shape. The segments overlap each other to provide improved scaffolding of the vessel wall and a greater flexibility during delivery. A composite stent having both balloon-expandable and self-expanding character has application in the venous system.

The invention relates to a blood pump for assisting blood flow in the heart, in particular to an artificial heart blood pump with magnetic and fluid dynamic pressure hybrid suspension, which comprises a casing 7 sleeved on an inner shell 9; wherein the casing comprises a motor stator 8 and the inner shell 9 comprises a head support component 1, a rotor component and a rear support component 15. The blood bump is characterized in that the rotor component, the head support component 1 and the rear support component 15 are arranged in the cylindrical inner shell 9; the rotor component is arranged between the head support component 1 the rear support component 15; wherein a head blood dynamic pressure suspension cone bearing 2 is positioned at the central head support component 1; the rotor component comprises a head blood dynamic pressure suspension cone 3, an impeller 6, a rear permanent magnet bearing inner ring 10 and a rear blood dynamic pressure suspension cone 13 in series; a rear blood dynamic pressure suspension cone bearing 14 is arranged at the central rear support component 15 and a rear permanent magnet bearing external ring 12 is embedded on the outside of the bearing. The blood pump has the advantages of low shearing force of the blood, less damage to blood erythrocytes and decreased hemolysis.

A high-molecular film covering on the surface of medical internal marmem supporter for insertion therapy is composed of internal, external and miniporous films. The said supporter has better elasticity, biological compatibility and medicine carrying power. It is used for esophagus, trachea, blood vessel, biliary trace and urethra.

The invention discloses an electromagnetic-permanent magnetism bidirectional driving type artificial heart pump employing artificial heart elastic blood sacs with simple structure and easy making; two nipple-shape bosses facing inwards and outwards are arranged on the elastic blood sac, and respectively provided with a central hole, thus replacing artificial heart valves of complex structures, and realizing unidirectional imbibition and unidirectional apocenosis; the artificial heart elastic blood sacs are driven by an electromagnetic-permanent magnetism bidirectional driving mechanism having only one armature, so the two elastic blood sacs are alternatively switch between a diastole work state and a contraction work state, thus alternatively realizing imbibition and apocenosis process, outputting pulse type blood flow like a natural heart, preventing technical directional errors of a continuous blood pump, and well simulating the work process of the natural heart; in addition, the elastic blood sacs are made of elastic telescopic materials, streamline form is realized inside, so cells in the blood cannot be damaged, and thromboses are hard to form, thus well replacing the work of a natural heart of a human being or vertebrate.

The invention relates to a drug coating balloon and a preparation method thereof. The drug coating balloon comprises a balloon body and a drug coating arranged on the outer surface of the balloon body. The drug coating comprises a bottom coating, an interlayer coating and a top coating which are sequentially stacked. The bottom coating is used for increasing the adhesion and firmness of the drug coating to the balloon body, so as to reduce the drug loss in the conveying process and increase the utilization rate of a drug. The interlayer coating is used for loading a drug and helping the drug to be better absorbed by tissues. The top coating is used for promoting the attachment of the drug coating and the intima of the vascular wall, so that the tissue absorption capability of the drug is better facilitated.

The invention provides a ventricular auxiliary device for the right heart of a child, belongs to the field of medical instruments, and solves the problems that an existing sliding bearing is prone to heating, blood coagulation is caused by heating, thrombus is further caused and the like, the ventricular auxiliary device comprises a pump cylinder and a rotor arranged in the pump cylinder, and a liquid inlet is formed in one end of the pump cylinder; a liquid inlet is formed in one end of the pump cylinder, a liquid outlet is formed in the other end of the pump cylinder, the rotor can rotate to enable blood to flow from the liquid inlet to the liquid outlet, the two ends of the rotor are connected with supporting pieces through rotating shafts, the supporting pieces are connected with the rotating shafts through bearings, and the bearings are provided with a plurality of open grooves. The magnetic core can be driven by in-vitro magnetic coupling driving equipment to rotate, and the magnetic core can rotate to drive the hub to rotate. The heating phenomenon at the joint of the rotating shaft and the bearing can be reduced, and thrombus is not prone to being generated.

The invention discloses a double-plunger cylinder driving artificial heart pump. An elastic haematodocha used for an artificial heart which is simple in structure and convenient in manufacturing is used, and two nipple-shaped bulges on the elastic haematodocha are used to replace a heart valve prosthesis which is extremely complex in structure, the inward nipple-shaped bulge and the outward nipple-shaped bulge being provided with holes on the center, thereby realizing one-way imbibition and one-way drainage. And the elastic haematodocha is driven by a double-plunger cylinder driving mechanism, so that the elastic haematodocha converts between a diastole operating state and a shrinkage operating state in turns, so as to realize processes of imbibitions and drainage in turns. The artificial heart pump can output impulse type blood flow similar to a natural heart, preventing technical directivity faults of a continuous blood pump, and preferably imitating operating process of a natural heart. The elastic haematodocha is made of an elastic scalable material, the internal of the elastic haematodocha is streamline, and would not damage cells in blood, and thrombus is not easy to form. The double-plunger cylinder driving artificial heart pump can preferably replace operation of a natural heart of a human or a vertebrate.

The invention relates to a vaneless blood pump. The vaneless blood pump comprises a volute, at least one separating piece, a rotor, a diversion piece and a power device; the volute is provided with a first cavity, a first liquid inlet and a first liquid outlet, wherein the first liquid inlet and the first liquid outlet are communicated with the first cavity; the separating piece and the rotor are arranged in the first cavity; the separating piece is provided with a second cavity, a second liquid inlet and a second liquid outlet, wherein the second liquid inlet and the second liquid outlet are communicated with the second cavity; the rotor is sleeved with the separating piece and fixedly connected with the separating piece through the diversion piece; a laminar flow channel is formed between the inner wall of the separating piece and the outer wall of the rotor. By supplying blood in this mode, the blood which needs to be supplied can flow in a laminar flow state, so that phenomena of hemolysis and thrombosis do not occur to the blood easily; meanwhile, the blood is not squeezed in the laminar flow mode, the damage to the blood is relatively small, long-term blood supplying can be conducted, the requirements of long-term blood supplying can be met, and the quality of the blood is ensured.

The invention relates to an artificial blood vessel and a preparation method thereof. The artificial blood vessel adopts a hollow circular pipe structure, and comprises a base layer, a binding layer and a bioglass layer which are sequentially connected from the inner part to the outer part, wherein the base layer adopts a styrene-isobutene block copolymer. The preparation method comprises the steps of performing injection molding, performing cleaning and drying, forming the binding layer and the bioglass layer and the like. The prepared artificial blood vessel is stable to exist in human bodies, and is good in bridging and suturing properties during operations, and thrombosis is not liable to form. Human tissue can rapidly admit and be compatible to form fixed tissue, and the artificial blood vessel has broad application prospects.

The invention provides an indwelling needle. The indwelling needle comprises an indwelling needle seat, an isolation plug, a catheter, a puncturing steel needle, a stop block, a plurality of limitingblocks and a baffle, wherein the indwelling needle seat comprises an inner cavity; the isolation plug is arranged in the inner cavity; the catheter is arranged at one end of the indwelling needle seat; one end of the puncturing steel needle punctures the isolation plug and extends out of the catheter; the stop block is clamped in the indwelling needle seat and abuts against the isolation plug; theplurality of limiting blocks are circumferentially arranged in one end, away from the catheter, of the indwelling needle seat; the baffle is arranged in the inner cavity and connected with the stop block through a spring, the spring sleeves the puncturing steel needle, and a plurality of openings matched with the plurality of limiting blocks in shape and size are formed in the edge of the baffle;the baffle is rotated, and when the plurality of openings in the baffle correspond to the plurality of limiting blocks, the plurality of openings in the baffle penetrate through the plurality of limiting blocks; the baffle is rotated, and when the plurality of openings in the baffle and the plurality of limiting blocks are staggered, the baffle is limited. The puncturing steel needle cannot puncture a medical worker due to protection of the spring, and medical infection is avoided.

The invention discloses a motor-bidirectional spiral-drive artificial heart pump. Through using an elastic haematodocha used for an artificial heart, the elastic haematodocha being simple in structure and convenient in manufacturing, two nipple-shaped bulges on the elastic haematodocha are used to replace a heart valve prosthesis which is extremely complex in structure, the inward nipple-shaped bulge and the outward nipple-shaped bulge being provided with holes on the center, thereby realizing one-way imbibition and one-way drainage. And the elastic haematodocha is driven by a motor-bidirectional spiral-drive mechanism, so that the elastic haematodocha converts between a diastole operating state and a shrinkage operating state in turns, so as to realize processes of imbibitions and drainage in turns. The artificial heart pump can output impulse type blood flow similar to a natural heart, preventing technical directivity faults of a continuous blood pump, and preferably imitating operating process of a natural heart. The elastic haematodocha is made of an elastic scalable material, the internal of the elastic haematodocha is streamline, and would not damage cells in blood, and thrombus is not easy to form. The motor-bidirectional spiral-drive artificial heart pump can preferably replace operation of a natural heart of a human or a vertebrate.