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Artificial blood vessel and preparation method thereof

A technology for artificial blood vessels and blood vessels, applied in the medical and health field, can solve problems such as adverse reactions, achieve good suture, wide application prospects, and maintain the effect of tissue metabolism

Active Publication Date: 2019-06-07
陈汉杰 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0020] The purpose of the present invention is to provide an artificial blood vessel and its preparation method in order to overcome the problems that the existing artificial blood vessels degrade in the human body and produce various adverse reactions

Method used

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  • Artificial blood vessel and preparation method thereof
  • Artificial blood vessel and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0056] refer to figure 1 , the artificial blood vessel is a hollow circular tube structure, which is composed of a base layer 1, an adhesive layer 2 and a bioglass layer 3 connected in sequence from the inside to the outside, wherein the base layer 1 is a styrene-isobutylene block copolymer, and the polystyrene block ratio is 20% by weight, the inner diameter is 4mm, and the thickness is 1.6mm. The bonding layer 2 is a thin layer of Dow Corning SILASTIC, and the thickness is 60 μm. TLC.

[0057] The artificial blood vessel exists stably in the human body, has good surgical bypass suturability, is not easy to form thrombus, can be quickly accepted by human tissues and is compatible with tissue fixation, and has broad application prospects.

Embodiment 2

[0059] An artificial blood vessel, which is a hollow circular tube structure, consists of a base layer 1, an adhesive layer 2 and a bioglass layer 3 connected in sequence from the inside to the outside, wherein the base layer 1 is a styrene-isobutylene block copolymer, and the polystyrene block The segment ratio is 15% by weight, the inner diameter is 10 mm, and the thickness is 1 mm. The adhesive layer 2 is a Dow Corning SILASTIC thin layer with a thickness of 70 μm. The biological glass layer 3 is 45S5 Bioglass (particle diameter is 300-500 μm) adsorbed on the surface of the adhesive layer 2 thin layer formed.

Embodiment 3

[0061] An artificial blood vessel, which is a hollow circular tube structure, consists of a base layer 1, an adhesive layer 2 and a bioglass layer 3 connected in sequence from the inside to the outside, wherein the base layer 1 is a styrene-isobutylene block copolymer, and the polystyrene block The segment ratio is 25% by weight, the inner diameter is 12 mm, and the thickness is 0.8 mm. The bonding layer 2 is a thin layer of Dow Corning SILASTIC, and the thickness is 80 μm. thin layer formed on the surface.

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Abstract

The invention relates to an artificial blood vessel and a preparation method thereof. The artificial blood vessel adopts a hollow circular pipe structure, and comprises a base layer, a binding layer and a bioglass layer which are sequentially connected from the inner part to the outer part, wherein the base layer adopts a styrene-isobutene block copolymer. The preparation method comprises the steps of performing injection molding, performing cleaning and drying, forming the binding layer and the bioglass layer and the like. The prepared artificial blood vessel is stable to exist in human bodies, and is good in bridging and suturing properties during operations, and thrombosis is not liable to form. Human tissue can rapidly admit and be compatible to form fixed tissue, and the artificial blood vessel has broad application prospects.

Description

technical field [0001] The invention relates to the medical and health field, in particular to an artificial blood vessel and a preparation method thereof. Background technique [0002] The development of artificial blood vessel (artificial blood vessel) began at the beginning of last century. When the blood vessels in a certain part of the human body cannot guarantee the normal blood supply to the human body due to reasons such as arteriosclerosis, embolism or damage, surgical operations such as blood vessel replacement, bypass or intervention are required. Autologous blood vessels were the first to be used for transplantation, but their sources were very limited. For this reason, scientists began to study artificial blood vessels. [0003] Scholars from various countries first used tubes made of metal, glass, polyethylene, silicone rubber and other materials to conduct a large number of animal experiments, but they have not been widely used clinically because they are pro...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L27/40A61L27/50A61L27/10A61L27/16A61L27/54
Inventor 陈汉杰顾梵
Owner 陈汉杰
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