Three-dimensional stephanoporate organization engineering bracket material, fibre cementing method preparing same and applications thereof

Abstract

The invention relates to a three-dimensional porous tissue engineering stent material, a fiber-gluing preparation method thereof and the application thereof, The material comprises poly butylene succinate and polycaprolactone; the weight portion is: poly butylene succinate 90 to 10 parts, polycaprolactone 10 to 90 parts; preparation: 1) mixing poly butylene succinate and polycaprolactone to obtain fiber by melt spinning; 2) cutting fiber and filling the fiber into a module, the fiber being arranged in an even structure; 3) putting the mould into a vacuum oven with 50 to 90 DEG C and keeping for 5 minutes to 1 hour, demoulding at room temperature and drying in vacuum after cooling, and obtaining three-dimensional tissue engineering stent material; 4) sterilizing and packing the three-dimensional porous tissue engineering stent material; The material has the application of being used as bone or cartilage tissue engineering cytoskeleton for repairing and rebuilding of bone or cartilage tissue organ. The tissue engineering stent material has evenly structured, internal pores that communicate with each other. The aperture of the pores is 10 to 500 Mum, and the porosity changes between 70 to 91 percent, so that the systematic structure of the stent is stable and easy to produce.

Description

technical field

[0001] The invention belongs to the field of tissue engineering scaffold material and its preparation, in particular to a three-dimensional porous tissue engineering scaffold material, its fiber bonding method preparation and application. Background technique

[0002] In daily life, the loss or failure of human tissues and organs is very common, which poses a serious threat to people's health and life. For a long time, human beings have been exploring and researching the use of materials and biotechnology to improve their own health. Traditional treatment methods include tissue and organ transplantation, surgical reconstruction, drug therapy, treatment with artificial substitutes and mechanical devices, etc., but these methods all have their obvious shortcomings. In the 1990s, with the development of cell biology, molecular biology, material science and related physical and chemical disciplines, tissue engineering was proposed as a new treatment method, and ...

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