Kukoline intravenous transfusion preparation

A technology for sinomenine and intravenous administration, which is applied in the direction of anti-inflammatory agents, drug delivery, non-central analgesics, etc., can solve problems such as hindering application and drug efficacy, improve clinical application safety, avoid adverse reactions, The effect of promoting widespread application
CN101347408AActive Publication Date: 2009-01-21李蕴麟
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
李蕴麟
Publication Date
2009-01-21

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Abstract

The invention provides a sinomenine injection special for intravenous administration. The sinomenine injection is an injection which comprises 0.005-0.3wt% of sinomenine and an aqueous solvent for injection, or an injection which comprises sterile injection powder or lyophilized injection powder used for preparation just before injection to cause the sinomenine concentration to be 0.005-0.3wt% in the injection and the aqueous solvent for injection. The sinomenine injection of the invention is used for treating rheumatism, chronic pain and other chronic inflammatory diseases. Compared with other existing injection forms, the sinomenine injection special for intravenous injection has lower drug adverse reaction, and the clinical curative effect is obviously improved.
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Description

technical field

[0001] The invention relates to a medicine for intravenous injection, in particular to an intravenous injection solution for treating rheumatism and other diseases with chronic inflammation pathological mechanism. Background technique

[0002] Sinomenine (sinomenine) is one of the alkaloids extracted from the stem and root of Sinomenium acutum (Thunb.) R. et Wils., a plant of Fangjiaceae, and is a known medicinal substance. Modern pharmacological studies have shown that sinomenine has a variety of pharmacological effects. In a nutshell, the main pharmacological effects of sinomenine known so far are as follows: anti-inflammatory, immunosuppressive, antihypertensive, central inhibitory, antiarrhythmic, etc.

[0003] Sinomenine hydrochloride has the following pharmacological effects:

[0004] 1. Anti-inflammatory effect: can inhibit acute exudation and chronic proliferative inflammation; can significantly inhibit the increase of 5-HT vascular permeability, in...

Claims

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