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Antihypelipidemic compound formulation

A compound preparation and hypoglycemic technology, applied in the field of compound oral preparations, to achieve the effects of promoting synthesis and storage, no toxic side effects, and balancing the energy metabolism of the body

Active Publication Date: 2012-01-25
SAILING PHARM TECH GRP CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are many hypoglycemic products on the market, but there is a lack of a product that can effectively reduce blood sugar in diabetic patients without causing hypoglycemic reactions and has a preventive effect

Method used

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  • Antihypelipidemic compound formulation
  • Antihypelipidemic compound formulation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] Take 10 parts of Polygonatum odoratum, 10 parts of Danzhu leaves, and 5 parts of bitter gourd, wash, extract with water, filter, blend, fill, test, and package to obtain the finished oral liquid.

[0013] Pharmacological test of this product:

[0014] 1. Effects on blood glucose in alloxan diabetic mice

[0015] 60 normal Kunming mice (body weight 22 ± 2g), 10 were randomly selected as the normal control group, and the remaining 50 were injected with alloxan 70mg / kg twice by the tail vein, and after 72 hours, the tail was cut and blood was taken to measure fasting blood sugar. Those whose blood sugar value was >18mmol / L were selected for the experiment, and 30 qualified diabetic mice were randomly divided into 3 groups, 10 in each group, which were model group, Xiaoke pill group and Erzhu Shengjinye group. The drug experiment group was administered by intragastric administration for 7 consecutive days, and the control group was given the same amount of water. The anima...

Embodiment 2

[0034] Take 5 parts of Polygonatum odoratum, 5 parts of Danzhu leaves, and 3 parts of bitter gourd, wash, extract with water, filter, blend, fill, test, pack, and obtain the finished oral liquid. The product of this embodiment has the same effect on diabetic patients.

Embodiment 3

[0035] Example 3: Take 18 parts of Polygonatum odoratum, 18 parts of Danzhu leaves, and 10 parts of bitter gourd, wash, mix, extract with water, filter, concentrate, dry, add auxiliary materials, mix evenly, granulate, and put into capsule shells to obtain capsules agent products. The product of this embodiment also has a remarkable effect on diabetic patients.

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PUM

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Abstract

The invention relates to a compound preparation for reducing blood sugar and belongs to the technical field of oral preparation. The product is characterized in that the compound preparation is prepared from the following traditional Chinese medicine materials in weight portion: 5 to 25 portions of polygonatum, 5 to 25 portions of herba lophatheri and 3 to 12 portions of balsam pear. Oral liquid is the preferred preparation form; and the compound preparation can also be prepared into different preparation forms. The product has a refined formula, can effectively reduce blood sugar of diabeticpatients without causing hypoglycemia reaction, has prevention function, and is mainly used for diabetic prevention and treatment. A safety test, a pharmacodynamic test, an acute toxicity test and a clinical test prove that the product can improve the activity of insulin and reduce the production of mutant insulin so that the product realizes physiological action with higher efficiency, promotes the ingestion and utilization of glucose by tissues and cells, and balances the energy metabolism of organism, thereby removing the symptoms of the diabetic patients. The product has remarkable effect, stability, safety, no toxicity, no side effect and can be taken for a long time.

Description

technical field [0001] The invention belongs to the technical field of compound oral preparations, and in particular relates to an oral preparation for lowering blood sugar made from active ingredients of Polygonatum Polygonatum, Bamboo Leaf and Bitter Melon. Background technique [0002] Diabetes Mellitus (DM) is a metabolic disease caused by the lack of insulin in the human body or the inability of insulin to function effectively. The onset of the disease is hidden, and often causes chronic complications to make people disabled and dead. It is one of the most common chronic diseases. With the improvement of people's living standards, the incidence of obesity increases, and the incidence of diabetes is increasing year by year. At present, there are many hypoglycemic products on the market, but there is a lack of a product that can effectively reduce blood sugar in diabetic patients without causing hypoglycemic reactions and has a preventive effect. It is of great signific...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/899A61P3/10
Inventor 魏玉玲
Owner SAILING PHARM TECH GRP CO LTD
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