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External preparation for skin and cleansing agent for skin

A technology for external skin preparations and skin cleansers, applied in the fields of external skin preparations and skin cleansers, can solve problems such as enhanced cosmetic irritation, skin astringency, redness, etc., and achieves good fusion, easy to rinse off, and stability. excellent effect

Inactive Publication Date: 2009-09-02
SHISEIDO CO LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0013] However, in detergents formulated with surfactants with strong detergency or solvents with strong dissolving power, there is a problem that, due to their strong dissolving power, stinging or redness occurs after washing, or increased Irritation from cosmetic products used thereafter
However, even when this specific oxyalkylene derivative is blended, problems such as a harsh feeling on the skin after washing still remain, and this is considered to be caused by the surfactant blended together.

Method used

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  • External preparation for skin and cleansing agent for skin
  • External preparation for skin and cleansing agent for skin
  • External preparation for skin and cleansing agent for skin

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0105] First, evaluation tests for usability and stability of the external preparation for skin of the present invention were performed.

[0106] First, the evaluation method of the external preparation for skin used in this test will be described. The application site of the skin external preparation is the cheek.

[0107] In addition, the composition of the conventional skin external preparation used as a control is as follows:

[0108] (water phase part)

[0109] (1) Glycerin 10.0% by mass

[0110](2) Carboxy vinyl polymer 0.1

[0111] (3) Potassium hydroxide 5.0

[0112] (4) Sorbitol 3.0

[0113] (5) Ethanol 4.0

[0114] (6) Purified water balance

[0115] (oil phase part)

[0116] (7) Liquid paraffin 5.0

[0117] (8) Glyceryl tri-2-ethylhexanoate 4.0

[0118] (9) Cetyl octanoate 2.0

[0119] (10) Appropriate amount of preservatives

[0120] (11) Appropriate amount of spices

[0121] (Evaluation 1): Skin lubricating feeling

[0122] With regard to the lubrica...

Synthetic example 1

[0223] Synthesis of Polyoxybutylene (30mol) Polyoxyethylene (30mol) Trimethylglyceryl Ether (Block Type Oxyalkylene Derivative)

[0224] 92 g of glycerin and 18 g of potassium hydroxide as a catalyst were put into the autoclave, and after replacing the air in the autoclave with dry nitrogen, the catalyst was completely dissolved at 140° C. while stirring. Next, 2160 g of butylene oxide was dripped with a dripping device, and stirred for 2 hours. Then, 1320 g of ethylene oxide was dripped with a dripping apparatus, and it stirred for 2 hours. Then add 400g of potassium hydroxide, replace the inside of the system with dry nitrogen, press-in 300g of methyl chloride at a temperature of 80-130°C, and react for 5 hours. Thereafter, the reaction composition was discharged from the autoclave, neutralized with hydrochloric acid, adjusted to pH 6 to 7, and treated at 100° C. under reduced pressure -0.088 MPa (gauge pressure) for 1 hour to remove contained water. In addition, in order ...

Synthetic example 2

[0227] Synthesis of Polyoxyethylene (57mol) Trimethylglyceryl Ether (Oxyalkylene Derivative)

[0228] 92 g of glycerin and 18 g of potassium hydroxide as a catalyst were put into the autoclave, and after replacing the air in the autoclave with dry nitrogen, the catalyst was completely dissolved at 140° C. while stirring. Next, 2508 g of ethylene oxide was dripped with a dripping device, and stirred for 2 hours. Then add 400g of potassium hydroxide, replace the inside of the system with dry nitrogen, press-in 300g of methyl chloride at a temperature of 80-130°C, and react for 5 hours. Thereafter, the reaction composition was discharged from the autoclave, neutralized with hydrochloric acid, adjusted to pH 6 to 7, and treated at 100° C. under reduced pressure -0.088 MPa (gauge pressure) for 1 hour to remove contained water. In addition, in order to remove the salt generated after the treatment, filtration was performed to obtain an alkylene oxide derivative.

[0229] The hydro...

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PUM

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Abstract

It is intended to provide an external preparation for skin, which has an effect of improving rough skin, and is excellent in feeling of use, particularly excellent in smoothness, free of stickiness, and excellent in stability. Further, it is intended to provide a cleansing agent for skin which is particularly excellent in usability, and has an excellent effect of removing cosmetics. That is, the external preparation for skin according to the invention is characterized by containing a block type alkylene oxide derivative represented by the following formula (I). Y-[O(EO)a-(AO)b-(EO)c-R]k (I) (In the formula, Y is a residue obtained by removing a hydroxy group from a polyhydric alcohol having 3 to 6 hydroxy groups, k is the number of hydroxy groups of the polyhydric alcohol, EO is an oxyethylene group, AO is an oxyalkylene group having 3 to 6 carbon atoms, and the respective groups are added in the form of a block. a k, b k and c k are average added mole numbers of oxyethylene group, oxyalkylene group having 3 to 6 carbon atoms and oxyethylene group, respectively, and satisfy the following relationships: 0 = a k = 100, 1 = b k = 100, 0 = c k = 100, with the proviso that (a+c) k > 1. The ratio of the total oxyethylene groups in the formula (I) to the sum of the total oxyethylene groups in the formula (I) and oxyalkylene groups having 3 to 6 carbon atoms is 10 to 80% by mass. The R groups may be the same or different and each is a hydrocarbon group having 1 to 4 carbon atoms.) Further, the cleansing agent for skin according to the invention is characterized by containing 0.01 to 70% by mass of a block type alkylene oxide derivative represented by the above formula (I) and 0.1 to 20% by mass of a moisturizing agent.

Description

[0001] related application [0002] This application claims the benefit of Japanese Patent Application No. 2006-269121 filed on September 29, 2006 and Japanese Patent Application No. 2006-269123 filed on September 29, 2006, which are incorporated herein by reference. technical field [0003] The present invention relates to external skin preparations and skin cleansers, and more particularly to improvements in skin external preparations and skin cleansers containing block type oxyalkylene derivatives as active ingredients. Background technique [0004] As important elements for evaluating an external preparation for skin, the function of maintaining a beautiful skin state and the feeling of use can be mentioned. On the other hand, as a typical method for attempting to improve the stability of the base, blending a surfactant can be cited. [0005] In order to maintain a beautiful skin condition, it is important to prevent or improve skin roughness, smooth out skin grooves an...

Claims

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Application Information

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IPC IPC(8): A61K8/86A61Q19/00A61Q19/10
Inventor 大森隆司石窪章勅使河原乔史杉山由纪八木荣一郎円山圭一田口须惠手塚洋二
Owner SHISEIDO CO LTD
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