Compound eardrops containing antipyrine and lidocaine the and preparation method thereof

Abstract

The invention discloses compound eardrops containing antipyrine and lidocaine and a preparation method thereof, which includes: antipyrine, lidocaine and pharmaceutically acceptable excipients, and contains 1%-20% antipyrine and 0.5%-5% lidocaine or salts thereof by total weight of compound eardrops. The compound eardrops containing antipyrine and lidocaine provided by the invention has the advantages of rapid action, fast effect, low cost, convenient usage, simple preparation, controllable quality as well as good antibacterial and anti-inflammatory effects for middle ear barotraumas and acuteand chronic otitis media, especially good recovery rate for middle ear barotraumas, and the compound eardrops has obvious analgesic effect for reducing earache, headache and other uncomfortable feelings of patients.

Description

technical field [0001] The invention relates to an ear drop, in particular to a compound ear drop containing antipyrine and lidocaine and a preparation method thereof. Background technique [0002] Acute and chronic otitis media are common and frequently-occurring diseases in clinical otology. Most of the pathogenic bacteria are Staphylococcus aureus, Pseudomonas aeruginosa, hemolytic streptococcus, Proteus, etc. Some otitis media may be accompanied by anaerobic bacteria, etc. Symptoms include temporary hearing loss and pain in the affected ear, or accompanied by fever, examination shows sunken or bulging or perforated tympanic membrane, disappearance of tympanic membrane light cone, middle ear effusion or effusion, tympanic membrane hyperemia or hemorrhage, and even In the case of tympanic membrane perforation, exudate or pus can be seen, and there is tenderness in the external auditory canal, mastoid, etc., or palpable enlarged lymph nodes around the ear, or accompanied by...

AI Technical Summary

Problems solved by technology

Although the application of glucocorticoids can help the treatment of otitis media, long-term use will cause adverse consequences such as hormone drug dependence and systemic hormone reactions, and it is not suitable for sports athletes. After use, it may cause athletes Doping test positive

Commonly used clinical otitis media treatment methods are not effective in analgesia

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