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Traditional Chinese medicine composition for treating peptic ulcer and preparation method thereof

A composition and technology of traditional Chinese medicine, applied in the field of traditional Chinese medicine composition for treating peptic ulcer and its preparation, can solve problems such as complicated etiology and pathogenesis, achieve obvious curative effect, clear effect, and reasonable drug prescription matching effect

Inactive Publication Date: 2010-01-27
NAVY MEDICINE RES INST OF PLA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The etiology and pathogenesis of GU are complex and have not yet been fully elucidated. Scholars at home and abroad have put forward a variety of hypotheses. Shay's theory of imbalance between attacking and defensive factors in gastric and duodenal mucosa is recognized by most scholars.

Method used

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  • Traditional Chinese medicine composition for treating peptic ulcer and preparation method thereof
  • Traditional Chinese medicine composition for treating peptic ulcer and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Clinical Observation of Treating Peptic Ulcer with Traditional Chinese Medicine Composition of the Present Invention

[0035] There were 226 patients, including 145 males and 81 females, all of them were gastric, duodenal ulcer or gastroduodenal compound ulcer by gastroscopic observation. Apply the traditional Chinese medicine capsule of the present invention orally 3 times a day, 2-6 capsules each time, one month is a course of treatment, after 2-3 courses of treatment, the treatment results are shown in the table below.

[0036] Treatment results:

[0037]

[0038]

[0039] Typical application cases:

[0040] Liu ××, male, 53 years old, chef, with a history of stomach pain for 27 years, was diagnosed with gastroduodenal ulcer. Gastroscopic examination found "two ulcers on the anterior wall of the duodenal bulb, hyperemia and edema of the upper corner of the posterior wall; hyperemia and edema of the gastric mucosa, accompanied by erosion and bleeding points." ...

Embodiment 2-6

[0043] Embodiment 2-6 prepares the active ingredient of Chinese medicine composition of the present invention

[0044]

[0045] Take the 6 herbs of Coptidis Rhizoma, Huoxiang, Zedoary, Aconite, Perilla, and Tangerine Peel, add 10-12 times the amount of 75% ethanol, soak for 1-2 hours, reflux extraction, filter; add 8 times the amount of 75% ethanol for the second time Reflux for extraction for 1 hour, and filter; the two filtrates were combined. The dregs of the above medicinal materials extracted by ethanol were added to 12 times of water, decocted for 2 hours, filtered, and the decoction was concentrated under reduced pressure (vacuum degree -0.08MPa, 60°C), concentrated to a relative density of 1.20-1.30 (50°C), Cool to room temperature, slowly add 98% ethanol to 60% alcohol concentration under stirring, refrigerate for 24 hours; filter, combine the filtrate with the above alcohol extract, recover the solvent under reduced pressure, concentrate to a relative densi...

Embodiment 7

[0046] The preparation of embodiment 7 Chinese medicine composition of the present invention

[0047] Capsules

[0048] The dry powder of the active ingredient prepared in Example 1 is pulverized and mixed evenly, and packed into hard gelatin capsules.

[0049] Granules

[0050] The active ingredient dry powder prepared in Example 3 was pulverized and mixed evenly, ethanol was added as a binder, starch was added as a filler, and then pressed into granules.

[0051] tablet

[0052] The active ingredient dry powder prepared in Example 6 is pulverized and mixed evenly, added with auxiliary materials to make granules, dried, sprayed with asarum volatile oil, and pressed into tablets.

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Abstract

The invention relates to the technical field of the traditional Chinese medicine, in particular to a traditional Chinese medicine composition for treating peptic ulcer and a preparation method thereof. The invention discloses a traditional Chinese medicine composition comprising 6 traditional Chinese medicines of coptis root, wrinkled gianthyssop, purple common perilla, rhizoma zedoariae, cooked radix aconiti praeparata and tangerine peel and the like, a preparation method and an application thereof. The medicine recipe of the traditional Chinese medicine composition has reasonable matching and definite function, and the traditional Chinese medicine composition has the functions of clearing away heat and toxic materials, warming the middle-jiao, dispelling cold, promoting blood circulation, dissolving stasis, promoting the circulation of qi, alleviating pain and the like. The traditional Chinese medicine composition has an integrative function in the aspects of preventing and treating acute and chronic gastropathy, duodenal ulcer and the like and has obvious curative effect.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating peptic ulcer and a preparation method thereof. Background technique [0002] Peptic ulcer (Peptic Ulcer, PU) includes gastric ulcer (Gastric Ulcer, GU) and duodenal ulcer (Duodenal Ulcer, DU). mucosal defect. Peptic ulcer, especially gastric ulcer, is a common and frequently-occurring disease in clinical practice. Its onset is closely related to the digestion of gastric acid and pepsin, and it can be found in any part in contact with acidic gastric juice. This disease is common all over the world. It is generally believed that about 10% of the population has suffered from PU in their lifetime, and it is on the rise year by year in our country. [0003] The etiology and pathogenesis of GU are complex and have not yet been fully elucidated. Scholars at home and abroad have put forward a variety of hypot...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61P1/04
Inventor 陈伟沈先荣蒋定文何颖栾洁李珂娴刘李娜钱甜甜
Owner NAVY MEDICINE RES INST OF PLA
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