51results about How to "The role is clear" patented technology

The invention relates to a diet for dietotherapy and health preservation which is prepared by medicine-food materials, and belongs to the field of nutrition and health preservation; the basic formula comprises the following raw materials on a dry weight basis: 30-60 parts of black sesame, 4-6 parts of poria cocos, 2-8 parts of hawthorn, 2-8 parts of medlar, 2-5 parts of coix seeds, 1-5 parts of spine date seeds, 2-5 parts of lotus seeds, 2-5 parts of Chinese yam, 1-5 parts of lily, 5-10 parts of jujube, 1-5 parts of donkey-hide gelatin, 1-4 parts of roses, 2-8 parts of carrots, 2-5 parts of walnut kernels, 2-5 parts of pumpkin seeds, 2-5 parts of black soybeans, 2-5 parts of black fungus, 1-3 parts of honeysuckles, 1-3 parts of sea-tangle, and 1-3 parts of mulberry. The invention can alsobe combined with other materials to form a secondary formula by using the basic formula as a main component. The formula of the invention is not excessively cold or hot, has a moderate character and taste, is convenient for using, has a less using amount, can be eaten frequently for a long term, has a lot of efficacy and effect and definite effect, and the efficacy is confirmed to reach the expectation and to be satisfied through long-term eating by a lot of people.

The invention discloses a traditional Chinese medicinal composition for treating lung cancer and liver cancer. The composition consists of rhizoma paridis yunnanensis extract, rhizoma curcumae longae extract and white paeony root extract according to a mass ratio of 1:(15-25):(5-15). Experiments prove that the traditional Chinese medicinal composition can obviously inhibit lung cancer cell lines such as LA795 and hepatoma cell lines such as Hep-B3 from growing, the half maximal inhibitory concentrations (IC50) of the lung cancer cell lines and the hepatoma cell lines can respectively reach below 20 micrograms / milliliter; tests on mouse models bearing lung adenocarcinoma and liver cancer tumors show that the lung adenocarcinoma and liver cancer inhibition rates are respectively above 50%, and the spleen index and liver index of mice are increased; and compared with raw medicinal materials which are separately applied, the medicinal composition has high anti-lung cancer and anti-liver cancer activities, an exact effect and a good inhibition effect on lung cancer and liver cancer.

The invention belongs to the technical field of processing of sweets, and particularly relates to cranberry-taste lutein ester sugarless soft sweets and a preparation method thereof. The cranberry-taste lutein ester sugarless soft sweets comprise the following raw materials of a gel coagulation agent, a sweetening agent, Chinese wolfberry fruit polysaccharide, citric acid, sodium citrate, lutein esters, a cranberry extract, purple sweet potato pigment, concentrated apple juice and concentrated cranberry juice. The prepared soft sweets have the efficacy of brightening eyes, alleviating eye weariness, caring skin, resisting oxidation, preventing cardiovascular diseases and the like.

The invention relates to medical applications of wedelolactone and derivatives thereof, in particular to the applications in preparing medicines for treating T-cell mediated immunologic injury diseases (chronic hepatitis or autoimmune hepatitis). Traditional Chinese Medicine eclipta has a function of liver protection; wedelolactone is prepared after the active ingredient of eclipta is traced and separated, so the pharmaceutical function is proved to be produced by wedelolactone; the structure of wedelolactone is determined through the spectrum properties and physicochemical properties. Wedelolactone is provided with biological activities: high selective inhibition to ConA stimulated T lymphocyte proliferation, no inhibition to normal peripheral blood lymphocyte (NPBL), and no cytotoxicity; wedelolactone is the active ingredient of Traditional Chinese Medicine with liver protection function; the method for preparing a novel medicine from the active ingredient of eclipta, wedelolactone, has the advantages of discarding the dross and selecting the essential, clear medicinal ingredients, definite function, safety and effectiveness, controllable quality, reducing the adverse drug reaction, and can be suitable for mass production.

The invention discloses a multifunctional chronic wound nursing and dressing dolly. The dolly comprises a body and wheels. The body sequentially comprises a material dressing layer, an operation layer, a cleaning layer and a collecting layer from top to bottom, the layers are connected with each other through supporting rods, and the wheels are arranged at the bottoms of of supporting rods; the dressing dolly is reasonable in structure and clear in use and is suitable for the orderly placing of medical items such as dressing materials for different chronic wounds and the like to facilitate taking; an operation table is wide and bright, so that dressing of a chronic wound is safe and sterile; medical workers can sterilize and clean hands, and different machinery and rubbishes related to dressing can be recovered. The dressing dolly is convenient to use and complete in functions, comprehensive services can be provided for the medical workers, the structure is not complicated, and the dressing dolly is suitable for industrial production and market popularization and use.

The invention relates to a pressed candy for improving the vitality of male sperms, and a production method thereof. The pressed candy comprises, by weight, 80-110 parts of selenium-rich bacterium powder, 80-120 parts of nutritional yeast powder, 8-15 parts of vitamin C, 60-70 parts of lycopene, 450-600 parts of fructose and 1100-1400 parts of auxiliary materials. Zinc-rich yeast, the selenium-rich bacterium powder, lycopene, VC and fructose are adopted as raw materials of the pressed candy for improving the vitality of male sperms, the raw materials are simple and have clear effects, zinc and selenium are from foods and can be well absorbed, and the selenium-rich bacterium powder has high selenium content and has no toxic or side effects. The pressed candy has the advantages of immunity enhancing, sperm generation and maturation prompting and male fertility enhancing effects, good safety, effectiveness, small toxic and side effects, long storage life, and convenience in taking and carrying; and the production method is simple, and is convenient for qualified production.

The invention discloses a traditional Chinese medicinal composition for treating lung cancer and liver cancer. The composition consists of rhizoma paridis yunnanensis extract and rhizoma curcumae longae extract according to a mass ratio of 1:(5-25). Experiments prove that the traditional Chinese medicinal composition can obviously inhibit lung cancer cell lines such as LA795 and hepatoma cell lines such as Hep-B3 from growing, the half maximal inhibitory concentrations (IC50) of the lung cancer cell lines and the hepatoma cell lines can respectively reach below 20 micrograms / milliliter; tests on mouse models bearing lung adenocarcinoma and liver cancer tumors show that the lung adenocarcinoma and liver cancer inhibition rates are respectively above 50%, and the spleen index and liver index of mice are increased; and compared with raw medicinal materials which are separately applied, the medicinal composition has high anti-lung cancer and anti-liver cancer activities, an exact effect and a good inhibition effect on lung cancer and liver cancer.

The invention discloses an extraction and purification method of dendrobium officinale leaf total flavone. The method includes following steps: mixing dendrobium officinale leaves with an alcohol water solution, performing backflow extraction, filtering, evaporating and concentrating filtrate, using petroleum ether and normal butanol to extract obtained concentrate, concentrating obtained extract,preparing a deionized water solution, using macroporous resin for adsorption and enrichment, using the alcohol water solution for elution, and concentrating eluate to obtain a dendrobium officinale leaf total flavone product. The total flavone after extraction and purification does not contain harmful impurities and is high bioactivity. The macroporous resin is renewable and reusable, alcohol obtained by evaporation and concentration can be reutilized, and little effluent pollution is caused in the process.

The invention discloses a traditional Chinese medicine composition having anti-lung cancer and anti-liver cancer effects. The traditional Chinese medicine composition is composed of a paris polyphylla extract, turmeric polysaccharides and a radix paeoniae alba extract in a weight ratio of 1: (0.1-5): (1-10). The in-vitro MTT (Methylthiazolyl Tetrazolium) assay activity tests proves that traditional Chinese medicine composition provided by the invention is capable of obviously inhibiting the growth of lung cancer cell lines such as LA795 and liver cancer cell lines such as Hep-B3; and lung adenocarcinoma and hepatocellular carcinoma-bearing mice model tests show that the anti-tumor rates of the traditional Chinese medicine composition both are more than 50%, and the traditional Chinese medicine composition is capable of improving the spleen index and the liver index of the mice, and obviously inhibiting pulmonary metastasis of subcutaneously transplanted tumors of the mice and causing apoptosis of tumor cells without any obvious toxic and side effects. Compared with single use of each raw material, the medicine composition is higher in anti-lung cancer and anti-liver cancer activity and clear in action, and has excellent inhibition effect on the lung cancer and the liver cancer.

The invention relates to a medicine composition for treating malignant tumors by injection administration. The medicine composition is characterized in that vitamin C is used as an anti-tumor component, and is compounded with one or multiple benzsulfamide compounds so as to prepare a pharmaceutically acceptable injection preparation for administration, or is compounded with one or multiple of benzsulfamide compounds for joint injection administration, especially for the tumor internal injection and interventional administration or vein, artery, muscle and subcutaneous administration. The vitamin C composition preparation has the advantages that the vitamin C composition preparation is directly injected into multiple malignant tumors of liver cancers, pancreatic cancers, brain tumors, esophagus cancers and the like, the medicine concentration in the tumor is increased, the medicine concentration in other tissues is decreased, the therapy effect is improved, and the toxic or side effect of a whole body is reduced; an effective method for overcoming the barriers of blood brain barriers, blood tumor barriers and the like is provided; an ideal therapy selection is provided for a patient of which the tumor cannot be cut off by surgery.

The invention discloses new application of Parissaponin VII. The new application has a preferable inhibiting effect on the growth of breast cancer cell strains and mouse transplantation tumor, and theapoptosis of breast cancer cells can be induced. The Parissaponin VII is high in breast caner activity resistance and obvious in effect, and simultaneously can be matched with a clinically accepted excipient, so that oral preparations (tablets, tinctures, dispersible powder, granules, emulsions, syrups, hard capsules, soft capsules and the like) or non-oral preparations (injections, sprays, pastes and the like) are prepared for the treatment of breast cancer.

The invention belongs to the technical field of biology and particularly relates to a maillard reaction product with functions of reducing blood glucose and blood pressure and application of the maillard reaction product. According to the maillard reaction product, arginine and glucose are utilized as reactants, and the maillard reaction product is prepared through maillard reaction. A preparing method comprises the steps of taking and solving a certain proportion of arginine and glucose in a water solution, continuously heating to enable the arginine and the glucose to react in a certain temperature for a certain time, carrying out instant high-temperature secondary reaction through a spraying process in a certain spraying technological condition and drying to obtain a target product. The maillard reaction product is artificially constructed with amino acid and reducing sugar as reactants, has functions of reducing blood sugar and blood pressure, is free of obvious toxic and side effects, effectively overcomes the defects that natural raw food materials or multicomponent matching raw materials are difficult to control in a producing process, is multiple in product and prone to generating toxic materials and is convenient to prepare, unique in product and clear in effect.

The invention discloses application of Tanshinone IIA serving as a human neuroastrocytoma resistant drug and relates to the field of medical sanitation. A principle component of the drug is Tanshinone IIA. Due to the in-vitro experiments for inhibiting growth of human neuroastrocytoma U251 and rat neuroastrocytoma C6, after the Tanshinone IIA acts on U-118MG cells, the survival rate of the U-118MG cells is gradually reduced along with increase of the concentration of the Tanshinone IIA and the prolonged action time. After the action time of the Tanshinone IIA reaches 48 hours, expression of Caspase 3 mRNA and proteins in the U-118MG cells is higher than that of negative control; the apoptosis rates of Tanshinone IIA groups with the concentrations of 10uM, 30uM and 100uM are respectively (9.8+ / -1.8)%, (16.5+ / -2.1)% and (23.2+ / -2.8)% and are all higher than (2.8+ / -1.1)% (P is less than 0.05) in the negative control. The experiments prove that the Tanshinone IIA serving as the human neuroastrocytoma resistant drug has clear effects and has an excellent effect of inhibiting the human neuroastrocytoma.

The invention discloses cordyceps sinensis health-care tea capable of tonifying kidney, moistening lung and tonifying qi. The cordyceps sinensis health-care tea comprises the following raw materials in parts by weight: 30-60 parts of cordyceps sinensis, 5-25 parts of raw astragalus membranaceus, 5-25 parts of polygonatum kingianum, 5-25 parts of mulberries, 5-25 parts of sea buckthorn, 5-25 partsof blueberries, 5-25 parts of honeysuckle, 5-25 parts of mint, 5-25 parts of pericarpium citri reticulatae, 5-25 parts of poria cocos, 5-25 parts of roses and 5-25 parts of tremella. The cordyceps sinensis has the effects of tonifying lung and kidney, relieving cough and reducing sputum, and the raw astragalus membranaceus has the effects of tonifying qi and lifting yang, consolidating superficiesand promoting salivation, and nourishing blood and removing stagnation, through organic matching with medicinal and edible health-care foods such as polygonatum kingianum, mulberry, hippophae rhamnoides, blueberry, honeysuckle, mint, dried orange peel, poria cocos, rose and tremella which have the effects of tonifying kidney and qi, nourishing yin and moistening lung, dispelling wind and clearingheat, regulating qi and activating blood, eliminating phlegm and promoting diuresis, the health-care effect on organisms is further enhanced, and drinking is convenient.

The invention belongs to the technical field of medicines, and particularly relates to a composition for treating bladder cancer. The composition for treating bladder cancer comprises the components in percentage by weight: 80-100% of active component and 0-20% of auxiliary materials, and the particle size of the composition for treating bladder cancer is 20-100 nanometers. The active component comprises the following raw materials in parts by weight: 200-500 parts of vinegar, 5-10 parts of dried rehmannia root, 5-10 parts of astragalus root, 2-5 parts of radix angelicae sinensis, 5-10 parts of herba polygoni avicularis, 2-5 parts of rhizoma alismatis, 2-5 parts of rhizoma chuanxiong, 2-5 parts of Polyporus, 2-5 parts of leech and 2-5 parts of cortex phellodendri. The nano-level composition for treating bladder cancer can improve the growth microenvironment of bladder tumor, regulate tumor immune metabolism, inhibit tumor cell proliferation and metastasis, and regulate the occurrence and development of bladder tumor through the synergistic compatibility of active substances in the active component.

The invention belongs to the field of medicinal chemistry and provides an application of ciglitazone in preparing drugs for treating pulmonary arterial hypertension. An experiment of the invention proves that ciglitazone is capable of effectively reducing average pulmonary artery pressure and pulmonary vasculature resistance of pulmonary arterial hypertension rats, increasing cardiac output, reducing right ventricular hypertrophy index, improving pulmonary vasculature remodeling and increasing protein expression of Gamma(peroxisome proliferation activated receptor, PPAR Gamma). The experimentproves that ciglitazone has a therapeutic effect on pulmonary arterial hypertension.

The invention provides a traditional Chinese medicine composition used for the infection recovery phase of novel coronavirus pneumonia. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 0.5-5 parts of radix ginseng, 1-30 parts of rhizoma dioscoreae, 2-15 parts of rhizoma polygonati, 1-15 parts of semen euryales, 2-30 parts of semen coicis, 3-10 parts of dried tangerine peel, 1-18 parts of fructus phyllanthi, 1-15 parts of fructus rosae normalis and 1-10 parts of black tea. Moreover, a prepartion method for the traditional Chinese medicine composition for the infection recovery phase of the novel coronavirus pneumonia is provided. Network research results of a component-target-pharmacological action mechanism of a formula of the traditional Chinese medicine composition used for the infection recovery phase of the novel coronavirus pneumonia link up with main symptoms consistently, and conform to the principle of modern precision medicine; and meanwhile, the traditional Chinese medicine composition has low cost, and meets the needs of industrial production.

The present invention provides an application of chrysanthemum total flavone in preparation of medicine for cuing arrhythmia. The chrysanthemum total flavone provided by said invention is effective component of chrysanthemum flower, the total flavone content is geater than 50%, and the dosage form prepared by using chrysanthemum flavone and medicinal exipient can be liquid preparation and solid preparation. Its therapeutic effect is obvious and reliable.

The invention discloses a wound surface liquid dressing and a preparation method thereof; the liquid dressing comprises bleached shellac, a plasticizer, gallate octacosyl ester (GA-C28) and a solvent system; the liquid dressing disclosed by the invention is a spraying type GA-C28 / bleached shellac wound surface liquid dressing prepared by taking the GA-C28 as an active component and taking the natural, nontoxic and degradable bleached shellac as a film-forming matrix; and the spraying type GA-C28 / bleached shellac wound surface liquid dressing can quickly form a film on the surface of skin, has good film permeability and liquid absorbability, has certain deformation resistance, has good anti-inflammatory and healing effects on wounds, is high in wound surface healing speed and healing rate, meets relevant requirements of national standards, satisfies the requirements on the wound surface liquid dressing in daily life and medical treatment, and has better the application prospect. The preparation method of the liquid dressing disclosed by the invention is simple to operate, mild in process condition and suitable for industrial large-scale production.

The invention relates to the technical field of blast load generator development, and provides a self-balancing structure for a medium-high pressure blast load generator. The self-balancing structurefor the medium-high pressure blast load generator is provided with an experiment section bottom assembling tool plate pre-buried in a foundation structure at the bottom of the blast load generator. Anexperiment section cylinder base is fixedly connected above the experiment section bottom assembly tooling plate; the self-balancing structure is further provided with long pull rod assemblies and short pull rod assemblies which are evenly distributed around the blast load generator. An experiment section cylinder body, a blast cavity cylinder body, a buffer element and a top cover of the blast load generator are fixedly connected above the experiment section cylinder body base in sequence; and a plurality of explosion drivers are arranged in the blast cavity barrel. The upper ends of the long pull rod assemblies and the short pull rod assemblies can be connected with the blast cavity cylinder through a quick-opening door lower meshing fluted disc; vibration and bounce of the main body structure of the blast load generator are effectively reduced so that the blast load generator is always in a self-balancing state, and the blast load generator is protected from being damaged.

The present invention provides an application of chrysanthemum total flavone in preparation of medicine for cuing arrhythmia. The chrysanthemum total flavone provided by said invention is effective component of chrysanthemum flower, the total flavone content is geater than 50%, and the dosage form prepared by using chrysanthemum flavone and medicinal exipient can be liquid preparation and solid preparation. Its therapeutic effect is obvious and reliable.

The present invention discloses inonotus obliquus and ginseng heart-nourishing, qi-benefiting and blood-activating healthcare tea. The tea comprises the following raw materials in parts by weight: 30-60 parts of inonotus obliquus, 5-25 parts of ginseng, 5-25 parts of raw radix astragali, 5-25 parts of fructus hippophae, 5-25 parts of rhizoma polygonati, 5-25 parts of radix puerariae, 5-25 parts offructus crataegi, 5-25 parts of flos lonicerae, 5-25 parts of mint, 5-25 parts of pericarpium citri reticulatae, 5-25 parts of poria cocos, 5-25 parts of radix platycodonis and 5-25 parts of radix glycyrrhizae. The inonotus obliquus with the effect of clearing heat, benefiting qi and nourishing yin and the ginseng with the effects of tonifying qi and nourishing the heart match with the raw radixastragali and the rhizoma polygonati with the effects of tonifying qi and consolidating superficies to improve the disease resistance, match with the fructus hippophae, the fructus crataegi and the radix puerariae with the effects of benefiting the spleen and promoting the secretion of body fluid to improve the respiration circulation function, match with the flos lonicerae and the mint with the effects of clearing heat and toxin to clear wind and heat, match with the pericarpium citri reticulatae and the poria cocos with the effects of regulating qi and benefiting the spleen to improve the respiration digestion function, and match with the radix platycodonis and the radix glycyrrhizae with the effects of clearing heat and relieving sore throat to expel phlegm for arresting cough.

The invention discloses inonotus obliquus-cordyceps sinensis health-care tea capable of warming yang, tonifying qi and dispelling cold. The health-care tea comprises the following raw materials in parts by weight: 30-60 parts of inonotus obliquus, 5-25 parts of cordyceps sinensis, 5-25 parts of raw astragalus membranaceus, 5-25 parts of raspberry, 5-25 parts of fructus alpiniae oxyphyllae, 5-25 parts of clove, 5-25 parts of dried ginger, 5-25 parts of blueberries, 5-25 parts of honeysuckle, 5-25 parts of mint, 5-25 parts of pericarpium citri reticulatae, 5-25 parts of poria cocos, 5-25 parts of platycodon grandiflorum and 5-25 parts of licorice root. According to the application, inonotus obliquus and cordyceps sinensis which have the effects of regulating the immune function, resisting bacteria and viruses and resisting oxidation to a certain extent are used as raw materials, and through organic matching with the raw astragalus membranaceus, the raspberries, the fructus alpiniae oxyphyllae, the cloves, the dried ginger, the honeysuckle, the mint, the blueberries, the pericarpium citri reticulatae, the poria cocos, the platycodon grandiflorum and the liquorice with effects of improving the immune function, resisting bacteria and viruses, enhancing fatigue resistance, resisting oxidation and improving the cardio-pulmonary function and the digestive tract function and the like, the nutrition is rich.

The invention provides an automatic triangular warning lamp device for motor vehicle parking. The automatic triangular warning lamp device for motor vehicle parking comprises a warning lamp assembly, a travel switch and a manual switch. A vehicle-mounted power source supplied power to the warning lamp assembly through a circuit. The travel switch and the manual switch are connected to a main line of the power supply circuit in series. The travel switch is in linkage with a parking hand brake device. When the parking hand brake device is in a parking brake state, the travel switch is turned on; and when the parking hand brake device is in a parking brake release state, the travel switch is turned off. Compared with a conventional double-flashing warning lamp, the automatic triangular warning lamp device for motor vehicle parking is simple in structure and has clear functions, and whether a vehicle is in a traveling state or a parking state can be distinguished; and when the vehicle is parked, the warming lamp is turned on automatically, the vehicle in the parking state can be displayed to the outside in time, a driver of a vehicle behind can correctly judge that the vehicle in front is in the parking state in time and take a proper vehicle driving measure, and rear-end collision is avoided.

The invention discloses the composition of a drug for external use for treating common skin diseases, and a preparation method of the drug. The drug is characterized by comprising the following raw materials by weight: 5 to 100 parts of radix sophorae flavescentis, 5 to 95 parts of herba hydrocotylis, 5 to 90 parts of coptis chinensis, 4 to 85 parts of bitter gourd, 3 to 80 parts of corydalis tuber, 2 to 75 parts of chili, 0.1 to 50 parts of frankincense, 0.1 to 50 parts of myrrh, and 100 to 5,000 parts of ethyl alcohol. Medicinal materials including the radix sophorae flavescentis, the coptis chinensis, the bitter gourd, the corydalis tuber and the chili are dried for 12 hours within the temperature range of 60-70 DEG C, smashed, screened through a 14-mesh sieve and then respectively dissolved in ethyl alcohol with a concentration of 50-95 percent, extraction is carried out within a temperature range of 50-85 DEG C, and filtering is carried out after sufficient extraction; the frankincense and the myrrh are respectively dissolved in ethyl alcohol with a concentration of 50-95 percent, extraction is carried out at the normal temperature, and filtering is carried out after sufficient extraction; leach liquors of the medicinal materials are mixed evenly according to a prescription ratio, and the volume is fixed at 1,000 milliliters through ethyl alcohol with a concentration of 50-95 percent; the drug can then be used after stewing, filtering and subpackaging. The drug has a simple composition and comprehensive effects in clearing heat, promoting diuresis, killing bacteria to diminish inflammation, promoting blood circulation to dissolve blood stasis, and relieving itching and pains, and is particularly suitable for treating common skin diseases in the special environment of armies.

The invention discloses application of galanin to preparation of a reagent for preventing cerebral ischemic stroke. The application is characterized in that in the reagent, galanin (GAL) or a galanin receptor (GalR1) is used as the effective constituent, and the reagent is injected into a lateral ventricle of an ischemic cerebral hemisphere when a brain stroke occurs suddenly or during cerebral ischemia surgery, so that the reagent can penetrate through the blood-brain barrier to directly act on ischemic brain tissue. By the adoption of the technical scheme, GAL is single in constituent and definite in effect as a short peptide, can be artificially synthesized easily, and has the advantage of being low in production cost.