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Silicone-hydrogel compound for soft contact lens and soft contact lens produced using the compound

A technology of soft contact lenses and silicon hydrogel, which is applied in the direction of eye implants, intraocular lenses, instruments, etc., can solve the problems of poor ductility and poor recovery ability, achieve good light transmittance, and solve the problem of wear and tear. Effect of extirpation, reduction of corneal edema and other diseases

Active Publication Date: 2010-03-31
BESKON KO +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] Due to the nature of the material of silicone hydrogel itself, its ductility is poor, and when it is used as a contact lens, it has poor recovery ability when deformed

Method used

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  • Silicone-hydrogel compound for soft contact lens and soft contact lens produced using the compound
  • Silicone-hydrogel compound for soft contact lens and soft contact lens produced using the compound
  • Silicone-hydrogel compound for soft contact lens and soft contact lens produced using the compound

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] Polymerization of N,O-bis(trimethylsilyl)acrylamide and 2-hydroxyethyl methacrylate

[0041] N, the amount of O-two (trimethylsilyl) acrylamide increases from 10g to 90g, every time increases 10g, the amount of 2-hydroxyethyl methacrylate reduces from 90g to 10g, every time reduces 10g, by This makes a mixture. 0.1-1 g of the initiator 2,5-dimethyl-2,5-bis(peroxy-2-ethylhexanoyl)hexane was dissolved to polymerize the mixture at 110° C. for 30 minutes.

[0042] The results showed that when 0.2 g (0.2% by weight) of the initiator and the above-mentioned substances were used, polymerization occurred regardless of the content of the initiator, but the initiator was independent of the transparency (compatibility). When more than 10 g (10% by weight) of N,O-bis(trimethylsilyl)acrylamide was used, the mixture solidified but was less compatible and became opaque milk color. The more N, O-bis(trimethylsilyl)acrylamide is used, the less likely it is to cure. In this way, the p...

Embodiment 2

[0045] Polymerization of N,O-bis(trimethylsilyl)acrylamide and N-vinyl-2-pyrrolidone

[0046] N, the amount of O-two (trimethylsilyl) acrylamide increases from 10g to 90g, every time increases 10g, the amount of N-vinyl-2-pyrrolidone decreases from 90g to 10g, every time reduces 10g, by This makes a mixture. 0.1-1 g of the initiator 2,5-dimethyl-2,5-bis(peroxy-2-ethylhexanoyl)hexane was dissolved to polymerize the mixture at 110° C. for 30 minutes.

[0047] The results showed that the mixture did not cure regardless of the amount of initiator used. The higher the amount of N,O-bis(trimethylsilyl)acrylamide used, the less likely curing will occur. This way, even though when polymerized, the mixture is as viscous as an adhesive, the mixture does not cure.

[0048] In the polymerization of this example, even if N,O-bis(trimethylsilyl)acrylamide and the water-soluble monomer N-vinyl-2-pyrrolidone were polymerized, the polymer did not cure. Such mixtures are not suitable for co...

Embodiment 3

[0050] Polymerization of N,O-bis(trimethylsilyl)acrylamide, 2-hydroxyethyl methacrylate and ethylene glycol dimethacrylate

[0051] N, the amount of O-two (trimethylsilyl) acrylamide increases from 10g to 90g, every time increases 5g, the amount of 2-hydroxyethyl methacrylate reduces from 90g to 50g, every time reduces 5g, again 0.1-1 g of crosslinker ethylene glycol dimethacrylate was added to the mixture. 0.2 g of the initiator 2,5-dimethyl-2,5-bis(peroxy-2-ethylhexanoyl)hexane was dissolved, and the mixture was polymerized at 110° C. for 30 minutes.

[0052] The results showed that with the increase of the amount of ethylene glycol dimethacrylate, the transparency (compatibility) and curing ability of the polymer increased, but the ductility became worse. In order to make the polymer suitable for making contact lenses, it is necessary to add ethylene glycol dimethacrylate in an amount of 0.5 g (less than 0.5% by weight). When the amount of N, O-bis(trimethylsilyl)acrylami...

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Abstract

The present invention relates to a silicone hydrogel composition for a soft contact lens and a soft contact lens using the same which comprises silicone N,O-bis(trimethylsilyl)acrylamide monomer and 2-hydroxyethyl methacrylate added with water soluble N-vinyl-2-pyrrolidone or N,N-dimethylacrylamide monoer to improve hydrophilic property and a cross-linking agent such as ethylene glyx>l dimethacrylate or divinyl benzene to provide a hydrophilic property, high water content rate, high oxygen permeability, good elongation and optical transmission.

Description

technical field [0001] The present invention relates to a kind of silicone hydrogel (silicone hydrogel) soft contact lens (soft contactlens), more particularly, the present invention relates to a kind of silicone hydrogel composition for soft contact lens and use this silicone hydrogel A soft contact lens of a gel composition, wherein the silicone hydrogel composition contains 2-hydroxyethyl methacrylate and N,O-bis(trimethylsilyl)propylene as monomers of a silicone resin amides. Background technique [0002] Generally, contact lenses are divided into hard lenses based on methacrylate (MMA) and soft lenses based on 2-hydroxyethyl methacrylate (HEMA). High oxygen permeability (oxygen permeability) and water content have been increasingly widely used. Since HEMA has a hydroxyl group (typical hydrophilic molecular structure) in the monomer, it is different from MMA, and HEMA has a higher water content (Refojo et., J.appl.Poly.Sd., 9: 2425 (1965) ),this is possible. [0003]...

Claims

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Application Information

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IPC IPC(8): C08L33/00C08L33/10C08L33/26
CPCG02B1/043C08F226/10C08F220/56C08F220/20C08F220/26C08F220/28C08F230/08C08L101/14C08L33/10C08L33/26C08L33/14C08F222/102C08F212/36C08F220/54A61F2/16
Inventor 南泽仁
Owner BESKON KO
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