System for monitoring intraocular pressure

A monitoring system and intraocular pressure technology, applied in the field of medical devices, can solve the problems of roughness, lack of sufficient and accurate basis for clinical diagnosis and treatment of glaucoma, and the discrepancy between the measurement results of the patient's normal physiological activities and the real situation, so as to avoid corneal damage. Effect

Inactive Publication Date: 2010-07-07
PEOPLES HOSPITAL PEKING UNIV
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AI Technical Summary

Problems solved by technology

Although doctors have worked tirelessly to measure intraocular pressure multiple times a day in an attempt to obtain the daily curve of intraocular pressure, it is conceivable that even if we can measure intraocular pressure 4-6 times a day, we can wake up the patient at night to measure Intraocular pressure, the result we get is still a rough result, and it may also cause the measurement result to be inconsistent with the real situation because it affects the patient's normal physiological activities (such as sleep)
Therefore, the current intraocular pressure measurement methods are not enough to provide a sufficiently accurate basis for the clinical diagnosis and treatment of glaucoma. More accurate measurement to better guide the diagnosis and treatment of glaucoma

Method used

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  • System for monitoring intraocular pressure
  • System for monitoring intraocular pressure
  • System for monitoring intraocular pressure

Examples

Experimental program
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Effect test

Embodiment 1

[0018] Example 1 Correlation detection between electrical properties of sclera surface and intraocular pressure

[0019] To examine the correlation between the chemical properties of the sclera surface and intraocular pressure, we performed ex vivo experiments using porcine eyes. Insert the needle connected to the connector (note: the connector is an infusion set connected to the atmosphere, filled with physiological saline, and the level of the liquid level can be adjusted) into the eye of the cadaver pig from the optic nerve, and the recording electrode is a needle-shaped electrode. At the sclera of the limbus, the reference electrode is a gold-plated plate electrode, which is placed at the sclera of the limbus at a distance of 5 mm from the recording electrode. The height of the perfusion bottle of the connector was changed to adjust the intraocular pressure, and the change of the electrical properties of the porcine sclera surface caused by the change of intraocular pressu...

Embodiment 2

[0023] Embodiment 2 intraocular pressure monitoring system

[0024] see Figure 5, the intraocular pressure monitoring system includes a pressure sensor 101, a signal receiver 102 and a signal reading recorder 103, wherein the pressure sensor 101 is implanted under the conjunctiva of the limbus, contacts with the scleral tissue, and directly senses changes in eyeball pressure; the pressure sensor 101 converts the pressure signal felt into a digital electrical signal and sends it out, which is received by the signal receiver 102 worn on the ear through wireless transmission and transmitted to the signal reading recorder 103 for processing to obtain the intraocular pressure value, and the intraocular pressure The value is displayed and stored.

[0025] The structure of the pressure sensor implanted in the eye is as follows: Figure 6 As shown, the flexible microelectrode array 2 and the signal processing and transmission unit are included, and the flexible microelectrode array...

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Abstract

The invention discloses a system for monitoring intraocular pressure. The system comprises a wireless pressure sensor and a portable signal receiving processor, wherein the wireless pressure sensor is implanted below the conjunctiva of limbus cornea and is directly contacted with an episcleral tissue; the pressure sensor comprises a flexible microelectrode array and a signal processing and transmitting unit; the flexible microelectrode array is used for sensing the impedance change of the surface of the episcleral tissue; the signal processing and transmitting unit is used for converting the impedance change into a voltage signal and processing and sending out the voltage signal; and the signal receiving processor is used for receiving the signal and analyzing and fitting the signal to acquire a numerical value of the intraocular pressure and storing and displaying the numerical value. The system for monitoring the intraocular pressure can automatically and continuously monitor the intraocular pressure of a patient for 24 hours without influencing the normal physical activity of the patient so as to provide sufficient and accurate data for clinical diagnosis and therapy. Furthermore, the pressure sensor is directly contacted with the episcleral tissue so as to avoid injury, infection, anoxia and the like of cornea when the pressure sensor is contacted with a corneal tissue for a long time.

Description

technical field [0001] The invention relates to a medical device, in particular to an implanted continuous intraocular pressure monitoring system. Background technique [0002] Glaucoma is the second leading cause of blindness worldwide. According to the report of the World Health Organization, there are 70 million people in the world suffering from glaucoma, and as the population ages, this number is expected to increase by 50% by 2020 (Quigley HA, Broman AT.The number of people with glaucoma worldwide in 2010 and 2020. Br J Ophthalmol. 2006 Mar; 90(3): 262-7.). Glaucoma is a group of diseases characterized by optic neuropathy accompanied by corresponding visual field defects. The increase of intraocular pressure is one of the primary factors of the disease. Therefore, it is also the most important clinical examination in the diagnosis and follow-up of glaucoma clinically. One of the indicators. At present, the relatively accepted standard method for measuring intraocula...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B3/16
Inventor 吴慧娟汤戎昱裴为华黎晓新陈宏达
Owner PEOPLES HOSPITAL PEKING UNIV
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