Composition of sodium ozagrel and polyethylene glycol and preparation method thereof
A technology of ozagrel sodium and polyethylene glycol, which is applied in the field of medicine, can solve problems such as poor stability, limited dosage, and easy precipitation, and achieve improved stability in vivo, improved effectiveness, and good brain targeting Effect
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Embodiment O
[0060] The preparation of embodiment OJ freeze-dried powder preparation
[0061] 1. Prescription
[0062] Prescription 1:
[0064] PEG-40000.008g
[0065] Mannitol 4g
[0066] Add water for injection to 1000mL
[0067]
[0068] A total of 1000 bottles were made
[0069] Prescription 2:
[0070] Sodium Ozagrel 20g
[0071] PEG-4000 0.02g
[0072] Mannitol 4g
[0073] Add water for injection to 1000mL
[0074]
[0075] A total of 1000 bottles were made
[0076] Prescription 3:
[0077] Sodium Ozagrel 40g
[0078] PEG-40000.08g
[0079] Mannitol 8g
[0080] Add water for injection to 1000mL
[0081]
[0082] A total of 1000 bottles were made
[0083] Prescription 4:
[0084] Sodium Ozagrel 40g
[0085] PEG-40000.4g
[0086] Mannitol 8g
[0087] Add water for injection to 1000mL
[0088] ...
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