Composition of plant extracts and application in skin whitening and moisture preservation

A technology of plant extracts and compositions, applied in drug combinations, skin care preparations, skin diseases, etc., to achieve the effects of exact whitening effect, convenient use, low allergy rate and inflammation rate

Inactive Publication Date: 2010-09-22
杭州千岛湖康诺邦健康产品有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Asiaticoside can effectively inhibit the mitosis and proliferation of melanocytes, in a dose-effect relationship, and can induce apoptosis or death of melanocytes; it can inhibit the activity of tyrosinase and melanin synthesis in melanoma cells, and is a cell-free Toxic skin depigmentation agent (Chinese Journal of Dermatology and Venereology of Integrated Traditional Chinese and Western Medicine, 2004, 3(1): 7-10), no medical application reports in this area have been found

Method used

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  • Composition of plant extracts and application in skin whitening and moisture preservation

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] The plant extract of the present invention is used to prepare skin whitening and moisturizing gel, and its formula is based on 100 parts: 2.5 parts of green tea extract, 1.25 parts of ginkgo leaf extract, 1.25 parts of centella asiatica extract, isononyl iso 10.0 parts of nonanol ester, 3.0 parts of Sepigel 305 (polyacrylamide), appropriate amount of preservative, and the rest is deionized water (up to 100 parts).

[0029] The specific process is as follows: dissolve green tea extract, ginkgo leaf extract, and centella asiatica extract in the ester, add Sepigel 305 when the temperature reaches 30°C, add water under stirring, finally add preservatives and stir well, cool to room temperature.

Embodiment 2

[0031]The plant extract of the present invention is used to prepare skin whitening and moisturizing gel, and its formula is calculated in 100 parts wherein: 2.5 parts of green tea extract, 1.25 parts of Ginkgo biloba extract, 1.25 parts of Centella asiatica extract, Carbopol 940 (cal. Wave 940) 1.0 parts, propylene glycol 9.0 parts, oleyl ether-201.5 parts, triethanolamine 2.0 parts, EDTA-Na 2 0.1 part, appropriate amount of preservative, and the rest is deionized water (add to 100 parts).

[0032] The specific process is as follows: in the case of rapid stirring, slowly sprinkle Carbopol 940 into part of deionized water to dissolve completely, and dissolve propylene glycol and preservatives with the remaining deionized water; pump the mixture of Carbopol 940 and deionized water into Vacuum emulsification tank, then filter deionized water, propylene glycol and preservatives into the vacuum emulsification tank, stir at 75°C-80°C, vacuumize and degas; when the above mixture is c...

Embodiment 3

[0034] The plant extract of the present invention is used to prepare skin whitening and moisturizing gel, and its formula is calculated in 100 parts: 0.2 part of green tea extract, 0.15 part of Ginkgo biloba extract, 0.15 part of Centella asiatica extract, Carbopol 940 (cal. Wave 940) 1.0 parts, propylene glycol 9.0 parts, oleyl ether-201.5 parts, triethanolamine 2.0 parts, EDTA-Na 2 0.1 part, appropriate amount of preservative, and the rest is deionized water (add to 100 parts).

[0035] Concrete technological process is the same as embodiment two.

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Abstract

The invention relates to a composition of plant extracts and application thereof in skin whitening and moisture preservation. The composition comprises the following active ingredients in percentage by weight: 5 to 90 percent of green tea extract, 5 to 50 percent of ginkgo leaf extract and 5 to 45 percent of centella extract, wherein the composition accounts for 0.5 to 20 percent when applied to preparing external products of skin, and the composition is uniformly mixed with medically-acceptable excipients or carriers in proportion to prepare products in forms of gel, cream, serosity, aqueous solution agents, emulsions or solids. The composition has the effects on skin whitening and moisture preservation without adding moisture preserving components; compared with products with similar application, the composition has stronger effects on skin whitening and moisture preservation and smaller dosage; the composition is safe, has no toxic or side effect, has low allergy rates and inflammation probability, penetrates into skin dermis, does not change the normal apoptosis process of cells, restrains tyrosinase, dopachrome tautomerase, DHICA oxidase and endothelin appropriately and balances the metabolism of melanin, so that the color and luster of the skin is more natural; and in addition, the generated skin whitening effect is definite, and the composition is convenient to use in cosmetics.

Description

technical field [0001] The invention relates to cosmetics and medicines for external skin products, in particular to a plant extract composition for skin whitening and moisturizing and its application to skin whitening and moisturizing. technical background [0002] The color of human skin depends on the content and distribution of melanin, and the structure, function and quantity of melanocytes directly affect the content of melanin in the skin, and are also the determining factors for the production of melanin. The principle of whitening is mainly to affect the metabolism of tyrosinase, melanocytes and melanin. At present, only hydroquinone (hydroq uinone) is regarded as the only formal whitening therapy in medicines, but some studies have shown that hydroquinone also has the possibility of causing cancer (Foreign Medical and Health Science Volume, 1994, 21(6): 321-324 ), most of the current medicines to solve the skin whitening problem rely on whitening cosmetics. The ma...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/97A61Q19/02A61Q19/00A61K36/82A61P17/16A61K8/9771A61K8/9789
Inventor 胡钢亮汤国霞张宁吴小鸯孙俊邵胜荣
Owner 杭州千岛湖康诺邦健康产品有限公司
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