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Use of nardostachys chinensis batal and extract thereof in preparation of medicaments for treating gastric ulcer

A technology of extract and gastric ulcer, which is applied in the field of preparation of medicines for treating gastric ulcer by Gansong and its extract, and achieves the effect of excellent drug effect, clear drug effect and wide clinical application range

Inactive Publication Date: 2013-02-27
CHENGDU UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] At present, there is no relevant report on the treatment of gastric ulcer with Gansong or its extract alone

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] The preparation method of embodiment 1 Nardinosa water extract of the present invention

[0023] Take 1000g of the original medicinal material of Gansong, add water to 8 times the amount, decoct for 1 hour, release the liquid medicine; add 8 times the amount of water to decoct for 2 hours, remove the medicinal residues, and combine the liquid medicine. After filtration, the pellet was centrifuged. Concentrate the medicinal solution to contain 4g / ml crude drug for later use.

Embodiment 2

[0024] The preparation method of embodiment 2 Nardina volatile oil of the present invention

[0025] Shake and sieve to remove the soil attached to the roots, and then add water to extract the volatile oil for 6 hours. After obtaining the volatile oil, remove the water at the bottom to obtain a yellow-green oil and bottle it for later use. The extraction method of volatile oil is extracted by "Chinese Pharmacopoeia" 2005 edition one appendix XD volatile oil determination method.

Embodiment 3

[0026] The preparation of embodiment 3 pharmaceutical tablet of the present invention

[0027] Get 160g of Nardinus water extract and 3.8g of Nizhny pine volatile oil, mix, granulate, add magnesium stearate, compress into tablets to obtain tablets.

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PUM

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Abstract

The invention provides the use of nardostachys chinensis batal and extract thereof in the preparation of medicaments for treating gastric ulcer. The invention also provides a medicinal composition for treating the gastric ulcer, which is a pharmaceutically common preparation prepared from the nardostachys chinensis batal or the extract of the nardostachys chinensis batal serving as an active ingredient and pharmaceutically acceptable auxiliary materials or auxiliary ingredients. The medicament of the invention has significant efficacy when used for treating the gastric ulcer, particularly when used for treating alcoholic gastric ulcer; in addition, pharmacological experiments prove that according to the compatibility of the extract of the nardostachys chinensis batal and the volatile oil of the nardostachys chinensis batal, synergetic effect is achieved and a novel clinical choice of the medicaments for treating the gastric ulcer is further provided.

Description

technical field [0001] The invention relates to a new application of nard pine, in particular to the application of nard pine and its extract in the preparation of medicine for treating gastric ulcer, which belongs to the field of medicine. Background technique [0002] Gastric ulcer refers to the limited injury of gastric mucosa that penetrates to the muscularis mucosa. It is one of the common peptic ulcer diseases. Gastric ulcer can occur alone or simultaneously with duodenal ulcer. The latter is called gastroduodenal compound ulcer. The size of the ulcer can range from several millimeters to several centimeters. The difference between it and erosion lies in the penetration The depth of erosion is more superficial and does not involve the muscularis mucosae. At present, people have in-depth research on the pathogenesis and clinical characteristics of gastric ulcer. 2 With the advent of receptor antagonists and proton pump inhibitors and the introduction of antibiotics, s...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/185A61P1/04A61K125/00
Inventor 胡晓梅杨松涛张旭杨奎何跃王久源唐灿
Owner CHENGDU UNIV OF TRADITIONAL CHINESE MEDICINE
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