7 results about "Nardostachys chinensis" patented technology

This invention provides a microemulsion gel of traditional Chinese medicine (TCM) compound essential oils, its preparation method, and its application, relating to the technical field of TCM compound essential oil preparations. Following TCM theory and based on the principle of syndrome differentiation and treatment, this invention yields a microemulsion gel of TCM compound essential oils composed of Bupleurum chinense essential oil, Citrus reticulata peel essential oil, Ligusticum chuanxiong essential oil, Murraya paniculata essential oil, and Nardostachys chinensis essential oil, which has the functions of soothing the liver and regulating qi, promoting blood circulation and relieving pain. Based on single-factor experiments, this invention uses response surface methodology to optimize the formulation of the TCM compound essential oil microemulsion gel, ultimately obtaining a uniform, stable, and easily spreadable microemulsion gel. The TCM compound essential oil microemulsion gel of this invention can effectively improve depressive-like behavior in mice under chronic unpredictable stress and reduce the levels of inflammatory factors in the CUMS mouse model, effectively improving the bioavailability of active ingredients in plant essential oils. This invention provides reference and guidance for the development of new dosage forms for the prevention and treatment of depression and the application of TCM essential oils.

The application provides a traditional Chinese medicine composition and application thereof in preparation of a drug for treating reflux esophagitis, and relates to the technical field of traditional Chinese medicine pharmacy.The traditional Chinese medicine composition takes Fritillaria thunbergii Miq., Evodia rutaecarpa, Citrus medica L. as monarch drugs, Inula japonica, Terminalia chebula Retz., Nardostachys chinensis, Syzygium aromaticum, Amomum subulatum, Phoenix tree as minister drugs, mother-of-pearl, Cortex Fraxini, Gentiana scabra Bunge, Osmanthus fragrans as auxiliary drugs, and Glycyrrhiza uralensis as a servant drug, and the drugs are combined to have the effects of dispersing the liver and harmonizing the stomach, reducing adverse and acid, and regulating cold and heat.The traditional Chinese medicine composition can significantly improve the esophagitis index of RE rats, has obvious inhibitory effect on inflammatory damage, can significantly improve the pathological morphology of the esophageal tissue of the RE rats, and realizes better anti-inflammatory and therapeutic effect on the RE rats.Meanwhile, the traditional Chinese medicine composition can significantly improve and alleviate the clinical symptoms of the patients with reflux esophagitis, such as acid reflux, heartburn, abdominal distension and belching, and reduce the frequency of the clinical symptoms.The traditional Chinese medicine composition is expected to be further developed and popularized as a drug for treating reflux esophagitis.

The invention discloses a small nucleic acid freckle-removing essence, which is carefully matched with active ingredients such as siRNA, NARDOSTACHYS CHINENSIS extract, nicotinamide, ascorbyl glucoside, tranexamic acid and the like, not only can block the generation of melanin from the source, but also can promote the metabolism of skin, accelerate the metabolism of generated melanin, and achieve internal and external synergism, so that the freckle-removing essence has the effects of removing freckle, removing freckle and removing freckle. A good removing effect is achieved on freckles, chloasma and other color spots.

This invention belongs to the field of traditional Chinese medicine compositions and relates to a composition for treating non-alcoholic fatty liver disease that clears the liver, invigorates the spleen, and removes blood stasis. The composition is composed of the following raw materials by weight: Artemisia capillaris 10-25g, Tea tree root 20-30g, Aristolochia debilis 20-30g, Earthworm 5-15g, Sophora japonica flower 5-15g, Bamboo shavings 5-10g, Nardostachys chinensis 3-6g, Lotus seed heart 3-6g, Ganoderma lucidum 6-12g, Prickly pear 10-15g, and Prepared licorice root 5-15g. This combination therapy, based on the concepts of "stasis, phlegm, stagnation, and deficiency" and the theory of inter-organ communication, treats non-alcoholic fatty liver disease by clearing the liver and relieving stagnation, strengthening the spleen and removing dampness, and promoting bowel movement. It also includes drugs that directly enter the liver meridian to invigorate blood circulation, remove blood stasis, and protect the body's vital energy, strengthen the spleen, and replenish deficiency. This combination of strengthening the spleen and clearing the liver, and invigorating blood circulation and removing blood stasis has a good therapeutic effect, with an effective rate of up to 97.83%. It is especially suitable for patients with non-alcoholic fatty liver disease of the phlegm-stasis type.

The invention provides a characteristic chromatogram of a heart-stabilizing traditional Chinese medicine composition and a construction method thereof, the construction method adopts high performance liquid chromatography, takes acetonitrile-water as a mobile phase, screens out reasonable chromatographic conditions, detects a reference substance solution and a test solution, realizes complete separation of a plurality of effective components, and improves the accuracy of the characteristic chromatogram of the heart-stabilizing traditional Chinese medicine composition. Five common peaks are identified and identified, and a characteristic spectrum is established; an original method for detecting chemical components in one or two of codonopsis pilosula, pseudo-ginseng and rhizoma nardostachyos is improved into a method capable of detecting the chemical components in the three components at the same time, so that the quality control of the heart-stabilizing traditional Chinese medicine composition and the preparation thereof is more comprehensive.

This invention relates to the field of compound essential oils of traditional Chinese medicine, and particularly to a compound essential oil of traditional Chinese medicine for the adjuvant intervention against Streptococcus pneumoniae and its preparation method. The raw materials include the following by weight: 3-8 parts of patchouli essential oil; 2-6 parts of clove essential oil; 2-5 parts of costus root essential oil; 2-6 parts of nard essential oil; 3-7 parts of calamus essential oil; 1-4 parts of asarum essential oil; 3-8 parts of peppermint essential oil; 2-6 parts of artemisia essential oil; 3-7 parts of eupatorium essential oil; 45-80 parts of base oil; 2-5 parts of solubilizer; and 1-3 parts of penetration enhancer. This invention addresses the core issues of "respiratory inflammation, sputum accumulation, and decreased body defense" caused by Streptococcus pneumoniae. Through the scientific formulation of active molecules from nine kinds of Chinese herbal essential oils, a comprehensive synergistic system is formed, which has the functions of "antibacterial and antiviral, anti-inflammatory and lung-clearing, expectorant and cough-relieving, and enhanced defense." It features strong synergistic activity of active molecules, high specificity, high retention and utilization rate of active molecules, safe and convenient use, wide applicability, and simple preparation process.

The invention discloses a rhizoma nardostachyos DNA fingerprint spectrum based on an SNP marker, a gene chip and application, and belongs to the field of molecular biology. The rhizoma nardostachyos genome SNP is obtained on the basis of GBS, 248 core SNP loci are identified, the SNP liquid-phase gene chip is developed through a targeted capture sequencing technology, the loci uniformly cover the genome, the representativeness, the polymorphism, the specificity and the universality are high, the gene chip is suitable for rhizoma nardostachyos variety identification, scientific support is provided for rhizoma nardostachyos variety management and quality detection, and the gene chip has a wide application prospect in the field of rhizoma nardostachyos variety identification. And a technical foundation is laid for germplasm resource analysis of rhizoma