Medicament for treating hyperthyroidism and preparation method thereof

A thyroid function and drug technology, applied in the direction of drug combination, pharmaceutical formula, medical preparation containing active ingredients, etc., can solve the problems of aggravating complications, hypocalcemic convulsions, scruples of isotope side effects, etc., to improve symptoms and signs, The effect of reducing toxic side effects and non-toxic side effects

Inactive Publication Date: 2010-11-24
GUANGANMEN HOSPITAL CHINA ACAD OF CHINESE MEDICAL SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, some methods for the treatment of hyperthyroidism have appeared, but each treatment method always has its defects: Western medicine antithyroid drug therapy has the disadvantages of long treatment period, large side effects, high recurrence rate, etc., which can cause drug-induced rash, inhibit white blood cells and even liver damage, etc.; Surgical therapy is suitable for patients with enlargement of the thyroid gland above II. If the operation is not careful, it will damage the recurrent laryngeal nerve, cause hoarseness, and even damage the parathyroid glands, causing hypocalcemic convulsions; radioisotope therapy is only suitable for patients over 25 years old. It takes 6 months to exert its due biological effect, and some patients are concerned about the side effects of isotopes; the latter two are at risk of lifelong hypothyroidism, aggravated exophthalmos and other complications
In short, although the above-mentioned treatments have played a good effect on the control of hyperthyroidism, they each have certain limitations and deficiencies.

Method used

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  • Medicament for treating hyperthyroidism and preparation method thereof
  • Medicament for treating hyperthyroidism and preparation method thereof
  • Medicament for treating hyperthyroidism and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] Embodiment 1 The preparation of the medicine (Jiakangning) for the treatment of hyperthyroidism of the present invention

[0041] 1. The active ingredient of the drug and the dosage of the active ingredient of the drug

[0042] Prunella vulgaris 400g Scrophulariaceae 300g Xanthophyll 240g

[0043] Fritillaria 300g raw oysters 600g.

[0044] Two, prepare pharmaceutical preparations according to the above-mentioned drug components and dosage:

[0045] 1. Add Prunella vulgaris, Xanthophyllum, and Fritillaria in the prescription with 9840ml of water, and extract 3 times with 90% ethanol under reflux, 1 hour each time. Filtrate, combine the filtrates, recover the ethanol and continue to concentrate to a liquid extract with a relative density of about 1.20 (70°C heat test), and set aside.

[0046] 2. Combine the dregs with raw oysters and scrophulariaceae in the prescription, add 20640ml of water to decoct 3 times, 2 hours each time, combine the decoction, filter, and conc...

Embodiment 2

[0047] Embodiment 2 The preparation of the medicine (Jiakangning) for the treatment of hyperthyroidism of the present invention

[0048] 1. The active ingredient of the drug and the dosage of the active ingredient of the drug

[0049] Prunella vulgaris 300g Scrophulariaceae 200g Xanthophyll 200g

[0050] Fritillaria 200g raw oysters 500g.

[0051] Two, prepare pharmaceutical preparations according to the above-mentioned drug components and dosage:

[0052] 1. Add Prunella vulgaris, Xanthophyll, and Fritillaria in the prescription with 9840ml of water, and 80% ethanol for reflux extraction 4 times, each time for 2 hours. Filtrate, combine the filtrates, recover ethanol and continue to concentrate to a liquid extract with a relative density of about 1.00 (70°C heat test), and set aside.

[0053] 2. Combine the dregs with raw oysters and scrophulariaceae in the prescription, add 20640ml of water to decoct twice, 2 hours each time, combine the decoction, filter, and concentrate...

Embodiment 3

[0054] Embodiment 3 The preparation of the medicine (Jiakangning) for the treatment of hyperthyroidism of the present invention

[0055] 1. The active ingredient of the drug and the dosage of the active ingredient of the drug

[0056] Prunella vulgaris 500g Scrophulariaceae 400g Xanthophyll 300g

[0057] Fritillaria 400g raw oysters 700g.

[0058] Two, prepare pharmaceutical preparations according to the above-mentioned drug components and dosage:

[0059] 1. Add Prunella vulgaris, Xanthophyllum, and Fritillaria in the prescription with 9840ml of water, and reflux 95% ethanol to extract twice, each time for 0.5 hours. Filtrate, combine the filtrates, recover the ethanol and continue to concentrate to a liquid extract with a relative density of about 1.40 (70°C thermal test) for subsequent use.

[0060] 2. Combine the dregs with raw oysters and scrophulariaceae in the prescription, add 20640ml of water and decoct 3 times, 3 hours each time, combine the decoction, filter, and...

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Abstract

The invention discloses a medicament for treating hyperthyroidism and a preparation method thereof. The medicament for treating hyperthyroidism of the invention is mainly prepared from the following raw material in part by weight: 300 to 500 parts of common selfheal fruit-spike, 200 to 400 parts of figwort root, and 200 to 300 parts of airpotato yam rhizome. The raw materials also include 200 to 400 parts of rhizoma bolbostemmae and / or 500 to 700 parts of raw oyster. Preferably, the medicament is prepared from the following raw materials in part by weight: 400 parts of common selfheal fruit-spike, 300 parts of figwort root, 240 parts of airpotato yam rhizome, 300 parts of rhizoma bolbostemmae and 600 parts of raw oyster. The medicament can be formed into any pharmaceutical formulation. The formulation is capsules. The medicament of the invention has the functions of nourishing yin, suppressing yang, detoxifying, eliminating goiter, reducing phlegm and resolving masses. The medicament can treat hyperthyroidism and is agreeable with patients incapable of bearing western medicaments.

Description

technical field [0001] The invention relates to traditional Chinese medicine, in particular to a medicine for treating hyperthyroidism and a preparation method thereof. Background technique [0002] Hyperthyroidism (hereinafter referred to as hyperthyroidism) is one of the common clinical diseases, which refers to a common, multiple-occurrence disease with increased nervous and mental excitability and enhanced metabolism as the main clinical manifestations caused by excessive synthesis and secretion of thyroid hormone by the thyroid gland. Endocrine and metabolic diseases are organ-specific autoimmune thyroid diseases. Toxic diffuse goiter (Graves Disease, GD) is the most common clinically, accounting for about 90% of hyperthyroidism. At present, some methods for the treatment of hyperthyroidism have appeared, but each treatment method always has its defects: Western medicine antithyroid drug therapy has the disadvantages of long treatment period, large side effects, high r...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8945A61K9/48A61P5/16A61K35/56A61K35/618
Inventor 林兰
Owner GUANGANMEN HOSPITAL CHINA ACAD OF CHINESE MEDICAL SCI
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