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Method for enhancing fermentation level of Bifidobacterium by utilizing lycopene

A technology of bifidobacteria and lycopene is applied in the direction of adding compounds to stimulate growth, which can solve the problems of no patent documents and reports, and achieve the effect of cost saving

Active Publication Date: 2013-01-23
上海邦成生物工程有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Regarding the fermentation method of bifidobacteria, there is no relevant patent literature report at present

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] (1) Dispersing lycopene with a content of 95% by weight into a uniform particle powder with a particle diameter of 1-3 mm.

[0027] (2) Take by weighing 10 grams of lycopene, 30 kg of glucose, 20 kg of peptone, 1 kg of dipotassium hydrogen phosphate, and 1 kg of salt, add it into a fermentation tank containing 1 ton of purified water, and adjust the pH to below 6.0 with phosphoric acid, after stirring and dissolving, After sterilizing at 121°C for 30 minutes, cool to 30°C.

[0028] (3) Inoculate 10 liters of the cultured bacterial solution, and control the temperature to 30° C. for anaerobic fermentation. When the pH naturally drops below 4.0, adjust the pH to about 4.5 with alkali. After 20 hours of fermentation, the reducing sugar decreased to 0.08%, and the bifidobacterium fermentation broth was obtained, and the count of viable bacteria in the fermentation broth was measured to be 31.2 billion / ml. Further, the fermented liquid was made into a solid bifidobacteria ...

Embodiment 2

[0030] (1) Dispersing lycopene with a content of 10wt% into a uniform particle powder with a particle diameter of 1-3 mm.

[0031] (2) Take by weighing 100 grams of lycopene, 40 kg of glucose, 30 kg of peptone, 1 kg of dipotassium hydrogen phosphate, and 1 kg of salt, add it into a fermentation tank containing 1 ton of purified water, and adjust the pH to below 6.0 with phosphoric acid, after stirring and dissolving, Sterilize at 121°C for 30 minutes and cool to 30°C.

[0032] (3) Inoculate 10 liters of the cultured bacterial solution, and control the temperature to 30° C. for anaerobic fermentation. When the pH naturally drops below 4.0, adjust the pH to about 4.5 with alkali. After 24 hours of fermentation, the reducing sugar decreased to 0.1%, and the bifidobacterium fermentation broth was obtained, and the count of viable bacteria in the fermentation broth was measured to be 40.5 billion / ml. Further, the fermented liquid was made into a solid bifidobacteria preparation b...

Embodiment 3

[0034] (1) Crush the tomato powder into a 20-mesh powder.

[0035] (2) Take by weighing 1kg of tomato powder powder, 30kg of glucose, 20kg of peptone, 1kg of dipotassium hydrogen phosphate, and 1kg of salt, add in a fermentation tank containing 1 ton of purified water, and adjust the pH to below 6.0 with phosphoric acid, after stirring and dissolving, 121 After sterilizing at ℃ for 30min, cool to 30℃.

[0036] (3) Inoculate 10 liters of the cultured bacterial solution, and control the temperature to 30° C. for anaerobic fermentation. When the pH naturally drops below 4.0, adjust the pH to about 4.5 with alkali. After 24 hours of fermentation, the reducing sugar decreased to 0.06%, and the bifidobacterium fermentation broth was obtained, and the count of viable bacteria in the fermentation broth was measured to be 35.2 billion / ml. Further, the fermented liquid was made into a solid bifidobacteria preparation by a conventional method, and the content of bifidobacteria was meas...

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PUM

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Abstract

The invention discloses a method for enhancing fermentation level of Bifidobacterium by utilizing lycopene, which comprises the following steps: (1) raw material pretreatment; (2) culture medium preparation; (3) high temperature sterilization; (4) cooling and inoculating; (5) fermentation; and (6) detection: when the content of reducing sugar in the fermentation liquid is lower than or equal to 0.1%, stopping the fermentation, thereby obtaining the Bifidobacterium fermentation liquid. In the invention, lycopene or a nutrient substance containing rich lycopene is used as the important component of the culture medium so as to culture the Bifidobacterium, thereby obviously enhancing the fermentation level of Bifidobacterium, shortening the fermentation cycle, realizing high density culture and obtaining more Bifidobacterium products. The viable count in the prepared Bifidobacterium fermentation liquid is 30-50 billion / ml; and the content of Bifidobacterium in the Bifidobacterium preparation is 20-40 billion / g. The products can be used as additives in feed additive industry.

Description

technical field [0001] The invention relates to a method for cultivating bifidobacteria, in particular to a method for improving the fermentation level of bifidobacteria by using lycopene. Background technique [0002] The research and application of live bacterial preparations is an important achievement in the field of biotechnology research in the feed industry, and it has also attracted more and more attention and favor from nutritionists. The reason is that people's demand for animal protein is increasing, but in actual life The raw materials for the production of feed are increasingly scarce, and the use of antibiotics will also bring certain side effects, so microbial growth promoters and probiotic feed additives have emerged as the times require. [0003] Bifidobacterium, as a microecological preparation, is more and more widely used in the feed industry. This product can improve the intestinal microecological system and improve the immunity of animals. In particula...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C12N1/38
Inventor 陆克文丰涛欧阳亮
Owner 上海邦成生物工程有限公司