Chlorine dioxide disinfectant oral spray and preparation method thereof

A technology of chlorine dioxide and mouth spray, which is applied in cosmetic preparations, oral care, and pharmaceutical formulations, etc. It can solve the problems of slow efficacy, unsatisfactory deodorization effect, difficulty in bleaching teeth, etc., and achieve rapid deodorization effect Effect

Active Publication Date: 2012-07-04
宋健
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Most of the oral disinfection and sterilization gargles and mouth sprays in the past contain ethanol, quaternary ammonium salts, Chinese herbal medicine extracts, and antibacterial drugs. It is also difficult to have the effect of bleaching teeth

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Example 1: A preparation method of chlorine dioxide disinfectant mouth spray, adopts the following process steps, and the formula ratio is calculated in parts by weight:

[0021] (1) Dissolve 0.15 parts of disodium ethylenediaminetetraacetic acid and 5 parts of glycerin in 100 parts of purified water to obtain solution A;

[0022] (2) Swell 0.15 parts of Carbomer 934P in solution A for 8 hours to prepare solution B;

[0023] (3) Add 5 parts of 2000ppm chlorine dioxide aqueous solution to solution B and stir evenly to obtain chlorine dioxide disinfectant spray. The stirring speed is 60 rpm and the stirring time is 30 minutes.

Embodiment 1

[0024] The in vitro antibacterial test of the chlorine dioxide disinfectant mouth spray obtained in Example 1 shows that it can kill Pseudomonas aeruginosa and Salmonella cholerae within 10 seconds; it can kill Escherichia coli, Staphylococcus aureus, Gonorrhoeae, and syphilis in 2 minutes Spirochetes, Trichomonas vaginalis, Streptococcus faecalis; the killing rate reached 99.99%. 5 points to kill HbsAg hepatitis virus, Bacillus subtilis black variant spores, the killing rate is 100%. In the bacteriostasis test on molds, the bacteriostatic effect time of the chlorine dioxide aqueous solution and the present invention was compared: around the transparent bacteriostatic zone, after 24 hours of incubation, the chlorine dioxide aqueous solution became blurred, but the present invention was still transparent , It shows that the antibacterial time of the present invention is significantly prolonged. This is because the present invention first kills microorganisms like the chlorine di...

Embodiment 2

[0025] Embodiment 2: A preparation method of chlorine dioxide disinfection mouth spray, adopts the following process steps, and the formula ratio is calculated in parts by weight:

[0026] (1) Dissolve 0.5 part of disodium ethylenediaminetetraacetic acid and 10 parts of glycerin in 200 parts of purified water to obtain solution A;

[0027] (2) Swell 0.5 part of Carbomer 934P in solution A for 12 hours to prepare solution B;

[0028] (3) Add 10 parts of a 2000ppm chlorine dioxide aqueous solution to solution B and stir evenly to obtain chlorine dioxide disinfectant spray. The stirring speed is 80 rpm and the stirring time is 20 minutes.

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PUM

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Abstract

The invention relates to a chlorine dioxide disinfectant oral spray and a preparation method thereof. The chlorine dioxide disinfectant oral spray is characterized by comprising the following components in portions by weight: 5-8 portions of chlorine dioxide water solution, 0.15-0.5 portion of carbomer 934P, 5-10 portions of glycerol, 0.15-0.5 portion of disodium edetate and 100-200 portions of purified water. The preparation method comprises the following steps: mixing the disodium edetate, the glycerol and the purified water to obtain a solution A; swelling the carbomer 934P in the solutionA to obtain a solution B; and adding the chlorine dioxide water solution to the solution B to obtain the chlorine dioxide disinfectant oral spray. The invention has the advantages of fast and enduring effects of sterilization, disinfection and deodorization, high safety, no toxicity, and broad spectrum and high efficiency for killing microbes in the oral cavity, and has bleaching action on yellowpigment spots on the tooth surface caused by tea drinking, smoking and the like.

Description

Technical field [0001] The invention relates to a disinfection mouth spray, in particular to a chlorine dioxide disinfection mouth spray and a preparation method thereof, belonging to the technical field of sterilization and disinfection agents. Background technique [0002] It is easy to accumulate and multiply various microorganisms in the mouth, tongue and taste bud mastoid gap, tooth gap, periodontal, and gum area. Some of them are pathogenic and can cause oral mucosal ulcers, gingivitis, periodontitis, angular cheilitis, oral odor and Smelly. Oral disinfection and sterilization are very important preventive measures to prevent the occurrence of the above diseases. Most of the previous oral disinfection and sterilization gargles and mouth sprays contain ethanol, quaternary ammonium salts, Chinese herbal extracts, and antibacterial drugs, but after use, the effects of sterilization, disinfection, and deodorization are slow and poor, and the effect of removing bad breath is n...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/81A61K8/22A61Q11/00
Inventor 宋健
Owner 宋健
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