Method for preparing extracted extractum for preparing drug for treating biliary tract infection

Abstract

The invention discloses a method for preparing extracted extractum for preparing drugs for treating biliary tract infection, comprising the following steps of: spreading the blended and extracted extractum into a baking pan according to 3-5 Kg / pan; setting the material temperature of a microwave vacuum drying sterilizer to 60-70 DEG C and operating time to 60-100 minutes, and drying to obtain dry extractum under the condition that vacuum degree is controlled between -0.08 MPa and -0.09 MPa; and crushing the dry extractum to surpass 100 meshes so as to obtain dry extractum powder. The invention adopts a microwave vacuum drying method, has the advantages of fast drying, high energy utilization ratio, good drying and sterilizing effect, high finished product quality, controllable production, high automation degree and good production environment, meets the requirements of GMP (Good Manufacturing Practice) and also greatly reduces the production cost.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, in particular to a method for drying extracts of medicines for treating biliary tract infection. Background technique [0002] In the production of modern traditional Chinese medicine, one of the most difficult problems for pharmaceutical companies is the drying of the extract. At present, pharmaceutical companies mainly use traditional oven vacuum drying or spray drying to dry extracts. These traditional drying methods have high drying temperature, high energy consumption, large equipment investment, long production cycle, low benefit, high cost, and land occupation. Issues such as large area. Therefore, extract drying has become a "bottleneck" in the production of pharmaceutical companies, limiting the development of production. [0003] In the prior art, the medicinal extract for treating biliary tract infection is dried in an oven. It was found that the difference bet...

AI Technical Summary

Problems solved by technology

It was found that the difference between the temperature of the upper space of the oven and the temperature of the lower space was more than 10°C, which caused the material to be heated unevenly; and the metal baking pan was placed directly on the heating pipe, and the actual temperature of the material at the bottom was much higher than the temperature of the oven. The temperature value measured by the table shows that the heat transfer between metal and metal is fast, the temperature of the material at the bottom is higher than the surface temperature of the material, and the surface of the material is heated unevenly, resulting in uneven quality of the dry paste

The drying temperature of the extract is controlled at about 80°C, and the drying time is long, which will easily cause the extract to be carbonized, the dry extract will have a burnt smell, and the active ingredients will be degraded or destroyed; the material will easily bubble out of the baking tray, and the extract will adhere tightly to the baking tray after drying. , not easy to collect and clean, heavy loss; water and electricity consumption is large, low efficiency; drying into drying, collecting paste requires many people to work together, labor intensity is high, and manpower consumption is high; Both equipment and personnel have potential safety hazards