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Calcium and zinc gluconate oral solution and preparation method thereof

A technology of calcium zinc gluconate and calcium gluconate, which is applied in pharmaceutical formulations, medical preparations with non-active ingredients, and medical preparations containing active ingredients, etc., can solve the problem of reducing drug quality, affecting drug absorption, and not considering drug taste problems, etc., to achieve the effect of better taste, reduced rejection, and sweet taste

Inactive Publication Date: 2011-05-04
HANGZHOU L TONJUN PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Not only does not consider the taste of the medicine, but it is also difficult to fully dissolve the raw materials, and the stability of the solution is not high, which seriously affects the absorption of the medicine in the human body, thereby reducing the quality of the medicine

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0012] A kind of calcium zinc gluconate oral solution, it is to use 54~66g calcium gluconate, 1.8~2.2g zinc gluconate, 9~11g lysine hydrochloride, 1.8~2.2g activated carbon, 135~165g sucrose, 10.8~13.2g Lactic acid, 0.9-1.1g sodium chloride and 0.45-0.55ml essence are prepared into 1000ml oral solution.

[0013] The preferred scheme is: it is prepared into 1000ml oral solution with 60g calcium gluconate, 3g zinc gluconate, 10g lysine hydrochloride, 2g gac, 150g sucrose, 12g lactic acid, 1g sodium chloride and 0.5ml essence.

[0014] The preparation method of aforementioned calcium zinc gluconate oral solution, it may further comprise the steps:

[0015] a. Take 1000ml of purified water, heat and boil for 30 minutes, release 500ml and set aside for later use. Add calcium gluconate and activated carbon, heat and stir to dissolve and reflux for 2 hours; then add lactic acid and sodium chloride, stir and dissolve and continue to reflux for half an hour, filter to obtain filtrate ...

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PUM

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Abstract

The invention discloses a calcium and zinc gluconate oral solution and a preparation method thereof and is characterized in that 54-66g of calcium gluconate, 1.8-2.2g of zinc gluconate, 9-11g of lysine hydrochloride, 1.8-2.2g of activated carbon, 135-165g of sucrose, 10.8-13.2g of lactic acid, 0.9-1.1g of sodium chloride and 0.45-0.55ml of essence are prepared into 1000ml of the oral solution. The calcium and zinc gluconate oral solution provided by the invention has good taste, is uniform and stable, and is beneficial to the absorption of a human body.

Description

technical field [0001] The invention relates to a calcium zinc gluconate oral solution and a preparation method thereof, in particular to an oral solution for preventing or treating calcium deficiency and zinc deficiency diseases and a preparation method thereof. Background technique [0002] Calcium deficiency can easily cause rickets, osteoporosis and other symptoms, while zinc deficiency can cause children's growth and mental retardation and loss of appetite. Currently on the market, the calcium zinc gluconate oral solution produced by Aonuo Pharmaceutical Co., Ltd. has a formula of calcium gluconate, zinc gluconate and lysine hydrochloride, such as the invention patent with the patent number 03104587. The calcium zinc gluconate oral solution is obtained by simply dissolving the above three raw materials in boiling water. Not only the mouthfeel of the medicine is not considered, but also it is difficult to fully dissolve the raw materials, and the stability of the soluti...

Claims

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Application Information

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IPC IPC(8): A61K31/191A61K9/08A61K47/26A61K47/46A61K47/02A61K47/12A61K47/04A61P3/14A61P3/12
Inventor 许伟
Owner HANGZHOU L TONJUN PHARMA
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