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Chinese medicinal composition for treating cardiovascular and cerebrovascular diseases and preparation method thereof

A technology for cardiovascular and cerebrovascular diseases and a composition, applied in the field of medicine, can solve the problems of expensive treatment and rising average mortality of patients

Active Publication Date: 2012-07-25
GUANGZHOU BOJI MEDICINE SERVICES
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although stents and bridges have temporarily passed the dangerous period for some critically ill patients, the average mortality rate of patients within five years has increased by 13% to 21.3% respectively, and the treatment is expensive, which is difficult for ordinary families to accept

Method used

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  • Chinese medicinal composition for treating cardiovascular and cerebrovascular diseases and preparation method thereof
  • Chinese medicinal composition for treating cardiovascular and cerebrovascular diseases and preparation method thereof
  • Chinese medicinal composition for treating cardiovascular and cerebrovascular diseases and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0156] Take 1000g of ginkgo leaves, 835g of hawthorn leaves and 500g of Chuanxiong, heat the ginkgo leaves and hawthorn leaves with 60% ethanol to 80°C to extract twice, filter, combine the filtrate, recover the ethanol from the filtrate under reduced pressure until it has no alcohol smell, add water to dissolve the concentrate , filtered after standing, D101 macroporous resin was applied to the filtrate, eluted with 75% ethanol, the eluate was collected, the eluate was decompressed to recover ethanol, dried under reduced pressure to obtain dry paste of ginkgo leaves and hawthorn leaves. Chuanxiong plus 80% ethanol was heated and refluxed twice, each time for 2 hours, filtered, and the filtrates were combined, and the filtrate was decompressed to recover the ethanol until it had no alcohol smell, alcohol precipitation, standing still, pouring out the supernatant, and reducing the supernatant The ethanol is recovered under pressure, and the auxiliary material is added to dry mic...

Embodiment 2

[0158] Take 900g of ginkgo leaves, 885g of hawthorn leaves and 580g of Chuanxiong, heat the ginkgo leaves and 70% ethanol to 60°C to extract twice, filter, combine the filtrate, recover the ethanol from the filtrate under reduced pressure until it has no alcohol smell, add water to dissolve the concentrate, and let it stand After filtering, apply FL-2 macroporous resin to the filtrate, elute with 85% ethanol, collect the eluate, recover the ethanol from the eluate under reduced pressure, and dry under reduced pressure to obtain dry ginkgo leaf paste. Hawthorn leaves plus 65% ethanol were refluxed twice, filtered, and the filtrates were combined, and the filtrate was decompressed to recover the ethanol until it had no alcohol smell. The concentrated solution was dissolved in water and filtered after standing. ethanol elution, collecting the eluate, recovering the ethanol from the eluate under reduced pressure, and drying under reduced pressure to obtain the dried hawthorn leaf p...

Embodiment 3

[0160] Take 750g of ginkgo leaves, 725g of hawthorn leaves and 350g of Chuanxiong, heat the ginkgo leaves and hawthorn leaves with 70% ethanol to 75°C for extraction twice, filter, combine the filtrate, recover the ethanol from the filtrate under reduced pressure until it has no alcohol smell, add water to dissolve the concentrate, After standing still, filter, apply FL-2 macroporous resin to the filtrate, elute with 85% ethanol, collect the eluate, recover ethanol from the eluate under reduced pressure, and dry under reduced pressure to obtain dry extracts of ginkgo leaves and hawthorn leaves. Chuanxiong plus 70% ethanol was heated and refluxed twice, each time for 2 hours, filtered, and the filtrate was combined, and the filtrate was decompressed to recover the ethanol until it had no alcohol smell, alcohol precipitation, standing still, pouring out the supernatant, and reducing the supernatant Ethanol was recovered under pressure, and microcrystalline cellulose was added to ...

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Abstract

The invention discloses a Chinese medicinal composition for treating cardiovascular and cerebrovascular diseases. The Chinese medicinal composition is prepared from the following raw materials in part by weight: 9 to 18 parts of szechuan lovage rhizome, 20 to 40 parts of ginkgo leaf and 18 to 30 parts of hawthorn leaf. The Chinese medicinal composition has the effects of promoting blood circulation and removing blood stasis, relieving turbidity and lowering fat and the like; and pharmacological experiments show that the Chinese medicinal composition has the obvious pharmacological effects of inhibiting platelet aggregation and thrombosis, lowering blood fat, preventing atherosclerosis, cerebral ischemia or myocardial ischemia, and the like, can be used for cerebral circulation insufficiency or the cerebral ischemia caused by cerebral atherosclerosis or thrombus, and can also be used for myocardial ischemic diseases caused by coronary atherosclerosis or thrombus. The Chinese medicinal composition has a good curative effect in clinic application.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a traditional Chinese medicine composition for treating cardiovascular and cerebrovascular diseases and a preparation method thereof. Background technique [0002] Cardiovascular and cerebrovascular diseases are common diseases that seriously threaten the health of human beings, especially middle-aged and elderly people. specialty. Cardiovascular and cerebrovascular diseases mainly include 11 diseases including hypertension, coronary heart disease, myocardial infarction, cerebral thrombosis, cerebral embolism and cerebral hemorrhage. It is caused by arteriosclerosis, hypertension, hyperlipidemia, hyperglycemia, hyperviscosity and microcirculation disturbance. At present, there are two main categories of drugs for the treatment of cardiovascular and cerebrovascular diseases: one is simple vasodilator drugs, long-term medication will cause the blood vessels to lose e...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/734A61P9/10
Inventor 马仁强周清马艺华陈培钦陈健文
Owner GUANGZHOU BOJI MEDICINE SERVICES
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