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Method for preparing compound salvia tablet

A technology of compound Danshen tablets and Danshen, which is applied to medical preparations containing active ingredients, pharmaceutical formulas, plant raw materials, etc., can solve the problems of long production cycle, low product qualification rate, and easy pollution, and achieve the goal of shortening the production cycle Effect

Inactive Publication Date: 2011-08-03
JIANGSU SUNAN PHARMA IND CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the current method of producing compound danshen tablets has a long production cycle, and is prone to pollution in the production process, and the qualified rate of the product is low

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Example 1: The raw materials were weighed according to the following parts by weight: 450 parts of Danshen, 141 parts of Sanqi, 8 parts of borneol, 85 parts of starch, and 2 parts of magnesium stearate; hours, filter the extract, recover the ethanol from the filtrate and concentrate it to 60°C when the relative density is 1.15-1.20, set aside; add 8-10 times the amount of water to decoct the dregs for 2 hours, filter the decoction, and concentrate the filtrate to 60 The relative density at ℃ is 1.30-1.32, and the supernatant paste is combined, and the relative density when concentrated to 60 ℃ is 1.33-1.35; grind the notoginseng, starch, borneol, magnesium stearate, sieve, and set aside; starch 1. Put Sanqi powder in a tank mixer, dry mix for 15 minutes, then add salvia miltiorrhiza extract and ethanol with a volume content of 95%, wherein the amount of ethanol added depends on the hardness of the soft material; wet mix for 15 minutes Soft material, granulation, YK160 s...

Embodiment 2

[0033] Embodiment 2: basically the same as Example 1, the difference is the consumption of raw materials, in parts by weight: 500 parts of Salvia miltiorrhiza, 160 parts of Radix Notoginseng, 10 parts of Borneolum, 100 parts of starch, 3 parts of magnesium stearate.

Embodiment 3

[0034] Embodiment 3: basically the same as Example 1, the difference is the consumption of raw materials, in parts by weight: 480 parts of Salvia miltiorrhiza, 150 parts of Panax notoginseng, 5 parts of Borneolum, 90 parts of starch, 1 part of magnesium stearate.

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PUM

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Abstract

The invention discloses a method for preparing a compound salvia tablet. The method comprises the following steps of: adding root of red-rooted salvia into ethanol at different concentrations in an amount which is 8 to 10 times that of root of red-rooted salvia, heating and refluxing for 1.5 hours, filtering extracting solution, recovering ethanol form filter liquor, and concentrating until the relative density is between 1.15 and 1.20 (at the temperature of 60 DEG C) for later use; decocting dregs of decoction in water in an amount which is 8 to 10 times that of the dregs of the decoction for 2 hours, filtering decoction, concentrating filter liquor until the relative density is between 1.30 and 1.32 (at the temperature of 60 DEG C), mixing the concentrated solution, and concentrating until the relative density is between 1.33 and 1.35 (at the temperature of 60 DEG C); grinding notoginseng root, starch, borneol and magnesium stearate into fine powder, and sieving; and putting the starch and the notoginseng root powder into a trough type mixing machine for dry mixing, adding root of red-rooted salvia extract and 95 volume percent of ethanol, performing wet mixing for 15 minutes, making soft materials, pelletizing, drying, tabletting and coating to obtain the compound salvia tablet. By the method, the production period can be shortened, and the product percent of pass can be improved; and by the coating process, the coating uniformity of the compound salvia tablet can be improved.

Description

technical field [0001] The invention relates to a preparation method of a traditional Chinese medicine preparation, in particular to a preparation method of compound salvia miltiorrhiza tablets for promoting blood circulation, removing blood stasis, regulating qi and relieving pain. Background technique [0002] Qi stagnation and blood stasis refer to the pathological state in which Qi stagnation and blood stasis coexist. Blood stasis can also be caused by blood stasis such as blood leaving the meridian, which affects the movement of qi. This means that there is blood stasis first, and qi stagnation is caused by blood stasis. form. Qi stagnation and blood stasis can easily lead to chest obstruction, coronary heart disease and angina pectoris, which can be life-threatening in severe cases. [0003] Compound Danshen Tablets are mainly used for promoting blood circulation and removing blood stasis, regulating qi and relieving pain. It is used for chest obstruction caused by q...

Claims

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Application Information

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IPC IPC(8): A61K36/537A61K9/28A61P9/10A61K31/045
Inventor 丁子君汤太平胡世成
Owner JIANGSU SUNAN PHARMA IND CO LTD
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