Compression nail for experimental animal model operation of cervical spondylosis

Abstract

The invention provides a compression nail for an experimental animal model operation of cervical spondylosis, belonging to the technical field of orthopedics. The compression nail is used for better simulating cervical spondylotic myelopathy caused by cervical disc herniation or ossification of posterior longitudinal ligament in an experimental animal model of cervical spondylosis. The invention adopts the following technical scheme: the compression nail provided by the invention comprises a nail cap and a nail body, wherein a filling hole is formed in the nail body; the filling hole is formed along the central axis of the nail body; one end of the filling hole is positioned at the upper part of the nail body, and the other end of the filling hole is opened at the tip of the nail body; and a filler in the filling hole is a developing biological material. The invention has the following beneficial effects: the compression nail can be used for better simulating cervical spondylotic myelopathy caused by cervical disc herniation or ossification of posterior longitudinal ligament, is simple and safe in surgical operations, has little damage to experimental animals, can not cause the rejection reaction of the animals, is suitable for various imaging examinations, has a simple structure, and is economical and practical.

Description

technical field [0001] The invention relates to an operation compression nail for an experimental animal model of cervical spondylosis, belonging to the technical field of orthopedics. Background technique [0002] Cervical spondylosis, also known as cervical syndrome, is a disease based on degenerative pathological changes. Mainly due to long-term cervical strain, bone hyperplasia, or intervertebral disc herniation, ligament thickening, resulting in cervical spinal cord, nerve root or vertebral artery compression, leading to a series of clinical syndromes of dysfunction. Cervical spondylotic myelopathy (CSM) is mainly due to cervical disc herniation, cervical vertebral osteophyte formation, ossification of posterior longitudinal ligament, hypertrophy of ligamentum flavum, cervical spinal canal stenosis, and cervical spine instability, which lead to compression of cervical spinal cord, blood vessels and other tissues. Syndrome arising from irritation. [0003] Currently, c...

AI Technical Summary

Problems solved by technology

However, due to the serious artifacts caused by metal nails, the CSM cannot be studied in detail by MRI examination, that is, MRI cannot be used for examination, which is the most serious defect of metal nails

Although resin nails and balloons are suitable for MRI examinations, they cannot be developed under X-ray and CT examinations, and the relationship between compression nails or balloons, the cervical spine and the spinal canal cannot be seen, which is also very inconvenient in practical applications

Although metal nails and resin nails are easy to control the size and depth of pressure, this method of artificially creating progressive compression by screwing screws in multiple operations is actually a subacute injury, and multiple operations will also reduce the severity of experimental animals. survival rate

[0005] On the whole, metal nails or resin nails are closer to cervical spondylotic myelopathy caused by cervical disc herniation or ossification of posterior longitudinal ligament clinically, but each has its own defects, which cannot meet the needs of basic research and clinical research on cervical myelopathy. All imaging studies of the disease

The balloon is not suitable for making models of cervical spondylotic myelopathy because of its compression range and degree are not easy to control

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